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- W2617688512 abstract "Background: Due to the increasing number of diabetes cases worldwide, there is an international concern to provide even more effective treatments to control this condition. Methods: This review brings together a selection of studies that helped to broaden the comprehension of various biological targets and associated mechanisms involved in type 2 diabetes mellitus. Results: Such studies demonstrated that QSAR techniques and virtual screenings have been successfully employed in drug design projects. Conclusions: Therefore, the main goal of this review is to give the state-of-art for the development of new drugs for the treatment of type 2 diabetes mellitus and to evaluate how computational tools, such as virtual screening and 3D-QSAR, can aid the development of new drugs with reduced adverse side effects. Keywords: Biological targets, computational chemistry, diabetes, drug design, QSAR, virtual screening." @default.
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- W2617688512 date "2017-11-08" @default.
- W2617688512 modified "2023-10-18" @default.
- W2617688512 title "The Role of QSAR and Virtual Screening Studies in Type 2 Diabetes Drug Discovery" @default.
- W2617688512 doi "https://doi.org/10.2174/1573406413666170522152102" @default.
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