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- W2617759474 abstract "Introduction: Atrial fibrillation (AF) is associated with significant morbidity, mortality and economic implications. Patientswith AF are often prescribed anticoagulants for the prevention of cardioembolic stroke and other embolic events. Patients’anticoagulation knowledge, level of medication adherence and health literacy are known to affect treatment outcomes.However, contemporary data regarding the relationships between these variables are lacking. Aims: The aim of this study was to determine the relationships between anticoagulation knowledge, health literacy andmedication adherence, and to investigate if knowledge is affected by health literacy levels. Methods: A cross-sectional survey was conducted in 48 patients with AF identified from general practices. TheAnticoagulation Knowledge Tool (AKT) was used to assess anticoagulation knowledge, the Short Test of Functional HealthLiteracy in Adults (s-TOHFLA) for health literacy and the 8-item Morisky Medication Adherence Scale (MMAS) for medicationadherence. The relationships between study variables were assessed using Pearson’s correlation coefficient, t-tests andregression analysis. Result: Participants in the study had mean scores of 61.6±15.8 for the AKT, 7.2±1.1 for the MMAS-8, and 24.7±9.5 for the sTOHFLA.A significant correlation was observed between both anticoagulation knowledge and health literacy with medicationadherence (0.45, p<0.01 and 0.36, p < 0.05, respectively). Participants with adequate health literacy had a significantly higherknowledge score than those with limited health literacy (66.1% vs 55.8%, p <0.05), and regression analysis showed that bothanticoagulation knowledge and health literacy scores were significant independent predictors of adherence levels(0.03(95%CI,0.01–0.05), p=0.001 and 0.04(95%CI, 0.01–0.07), p= 0.01, respectively). Discussion: Anticoagulation knowledge, health literacy and medication adherence were closely related and suboptimal inpatients with AF. Further research in a larger population is required to definitely elucidate the magnitude of this problem.Future studies should also focus on developing effective interventions to improve anticoagulation knowledge, health literacyand medication adherence in this patient population." @default.
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- W2617759474 date "2017-07-01" @default.
- W2617759474 modified "2023-10-01" @default.
- W2617759474 title "The relationship between anticoagulation knowledge, health literacy, and medication adherence in patients with atrial fibrillation" @default.
- W2617759474 doi "https://doi.org/10.1016/j.sapharm.2017.04.020" @default.
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