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- W2617776585 abstract "e15008 Background: Current recommendations for advanced ( > T2) gastric cancer treatment include administration of neoadjuvant chemotherapy (NAC) following a landmark trial in 2006. This study evaluates the rate of use as captured by a large U.S. cancer database and whether use changed after 2006. Methods: The National Cancer Database from 2003-2012 was used to identify patients with a diagnosis of gastric cancer and restricted to those who underwent definitive gastrectomy (SURG), with complete data. The NAC cohort was defined as receipt of chemotherapy within six months prior to SURG. NAC patients were compared to those who underwent SURG only or SURG followed by adjuvant chemotherapy. Results: 16,128 patients were identified: 5,909 (36.7%) underwent NAC; 7,077 (43.9%) underwent SURG only and 3,142 (19.5%) underwent SURG followed by chemotherapy. The utilization of NAC increased annually, from 25.9% in 2003 to 46.3% in 2012, with an increased likelihood for receiving NAC after 2003, Odds Ratio 1.71, p < ..." @default.
- W2617776585 created "2017-06-05" @default.
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- W2617776585 date "2015-05-20" @default.
- W2617776585 modified "2023-09-27" @default.
- W2617776585 title "Trends in utilization of neoadjuvant chemotherapy for gastric cancer: An analysis of the U.S. National Cancer Database." @default.
- W2617776585 doi "https://doi.org/10.1200/jco.2015.33.15_suppl.e15008" @default.
- W2617776585 hasPublicationYear "2015" @default.
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