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- W2617816095 abstract "In order to evaluate the isoform selectivity of novel inhibitors within the c-Jun N-terminal kinase (JNK) family, a fluorescence polarization-based competition binding assay, previously developed for JNK3, was extended to the other isoforms JNK1 and JNK2. The assay is based on the displacement of a versatile fluorescent pyridinylimidazole-based probe and was validated by testing the precursor of the probe as well as standard JNK inhibitors." @default.
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- W2617816095 date "2017-09-01" @default.
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- W2617816095 title "Fluorescence polarization-based competition binding assay for c-Jun N-terminal kinases 1 and 2" @default.
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- W2617816095 doi "https://doi.org/10.1016/j.ab.2017.05.022" @default.
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