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• W2617892439 startingPage "2107" @default.
• W2617892439 abstract "Sarcopenia has recently emerged as a new condition that, independently from malnutrition, may adversely affect the prognosis of cancer patients. Purpose of this narrative review is to define the prevalence of sarcopenia in different primaries, its role in leading to chemotherapy toxicity and decreased compliance with the oncological therapy and the effect of some drugs on the onset of sarcopenia. Finally, the review aims to describe the current approaches to restore the muscle mass through nutrition, exercise and anti-inflammatory agents or multimodal programmes with a special emphasis on the results of randomized controlled trials. The examination of the computed tomography scan at the level of the third lumbar vertebra-a common procedure for staging many tumours-has allowed the oncologist to evaluate the muscle mass and to collect many retrospective data on the prevalence of sarcopenia and its clinical consequences. Sarcopenia is a condition affecting a high percentage of patients with a range depending on type of primary tumour and stage of disease. It is noteworthy that patients may be sarcopenic even if their nutritional status is apparently maintained or they are obese. Sarcopenic patients exhibited higher chemotherapy toxicity and poorer compliance with oncological treatments. Furthermore, several antineoplastic drugs appeared to worsen the sarcopenic status. Therapeutic approaches are several and this review will focus on those validated by randomized controlled trials. They include the use of ω-3-enriched oral nutritional supplements and orexigenic agents, the administration of adequate high-protein regimens delivered enterally or parenterally, and programmes of physical exercise. Better results are expected combining different procedures in a multimodal approach. In conclusion, there are several premises to prevent/treat sarcopenia. The oncologist should coordinate this multimodal approach by selecting priorities and sequences of treatments and then involving a nutrition health care professional or a physical therapist depending on the condition of the single patient." @default.
• W2617892439 created "2017-06-05" @default.
• W2617892439 creator A5072747996 @default.
• W2617892439 date "2017-09-01" @default.
• W2617892439 modified "2023-10-16" @default.
• W2617892439 title "Forcing the vicious circle: sarcopenia increases toxicity, decreases response to chemotherapy and worsens with chemotherapy" @default.
• W2617892439 cites W1176825293 @default.
• W2617892439 cites W1480855396 @default.
• W2617892439 cites W1493883088 @default.
• W2617892439 cites W1495487817 @default.
• W2617892439 cites W1534768439 @default.
• W2617892439 cites W1537308241 @default.
• W2617892439 cites W1561929167 @default.
• W2617892439 cites W1575132822 @default.
• W2617892439 cites W1588875235 @default.
• W2617892439 cites W1597609467 @default.
• W2617892439 cites W1684577264 @default.
• W2617892439 cites W1747670871 @default.
• W2617892439 cites W1788749837 @default.
• W2617892439 cites W1801972054 @default.
• W2617892439 cites W187579815 @default.
• W2617892439 cites W1898606210 @default.
• W2617892439 cites W1911388308 @default.
• W2617892439 cites W1934992232 @default.
• W2617892439 cites W1950421495 @default.
• W2617892439 cites W1964440334 @default.
• W2617892439 cites W1964900534 @default.
• W2617892439 cites W1965907872 @default.
• W2617892439 cites W1967412279 @default.
• W2617892439 cites W1968598018 @default.
• W2617892439 cites W1975648347 @default.
• W2617892439 cites W1978713285 @default.
• W2617892439 cites W1978731308 @default.
• W2617892439 cites W1978885717 @default.
• W2617892439 cites W1979666460 @default.
• W2617892439 cites W1980683095 @default.
• W2617892439 cites W1985388571 @default.
• W2617892439 cites W1991020867 @default.
• W2617892439 cites W1991419609 @default.
• W2617892439 cites W1991601270 @default.
• W2617892439 cites W1992234322 @default.
• W2617892439 cites W1992818577 @default.
• W2617892439 cites W1996482324 @default.
• W2617892439 cites W1996618335 @default.
• W2617892439 cites W1997155298 @default.
• W2617892439 cites W2002911924 @default.
• W2617892439 cites W2003861472 @default.
• W2617892439 cites W2003978548 @default.
• W2617892439 cites W2005636762 @default.
• W2617892439 cites W2005815716 @default.
• W2617892439 cites W2006782694 @default.
• W2617892439 cites W2011225645 @default.
• W2617892439 cites W2012113498 @default.
• W2617892439 cites W2014053695 @default.
• W2617892439 cites W2016177875 @default.
• W2617892439 cites W2017294919 @default.
• W2617892439 cites W2019483360 @default.
• W2617892439 cites W2021929534 @default.
• W2617892439 cites W2024674453 @default.
• W2617892439 cites W2026475551 @default.
• W2617892439 cites W2026956668 @default.
• W2617892439 cites W2028050936 @default.
• W2617892439 cites W2028802149 @default.
• W2617892439 cites W2030387756 @default.
• W2617892439 cites W2031808191 @default.
• W2617892439 cites W2033905986 @default.
• W2617892439 cites W2034200903 @default.
• W2617892439 cites W2036610278 @default.
• W2617892439 cites W2041487861 @default.
• W2617892439 cites W2043583700 @default.
• W2617892439 cites W2043737378 @default.
• W2617892439 cites W2046387692 @default.
• W2617892439 cites W2046529949 @default.
• W2617892439 cites W2047427543 @default.
• W2617892439 cites W2047906861 @default.
• W2617892439 cites W2049190054 @default.
• W2617892439 cites W2054865212 @default.
• W2617892439 cites W2056459754 @default.
• W2617892439 cites W2056763070 @default.
• W2617892439 cites W2058720365 @default.
• W2617892439 cites W2059426130 @default.
• W2617892439 cites W2062296199 @default.
• W2617892439 cites W2062470198 @default.
• W2617892439 cites W2064824453 @default.
• W2617892439 cites W2068037891 @default.
• W2617892439 cites W2068357511 @default.
• W2617892439 cites W2069539051 @default.
• W2617892439 cites W2073096992 @default.
• W2617892439 cites W2074022820 @default.
• W2617892439 cites W2078608486 @default.
• W2617892439 cites W2087917241 @default.
• W2617892439 cites W2090991937 @default.
• W2617892439 cites W2092361675 @default.
• W2617892439 cites W2093970255 @default.
• W2617892439 cites W2095152203 @default.
• W2617892439 cites W2097501147 @default.
• W2617892439 cites W2098103731 @default.
• W2617892439 cites W2104357394 @default.

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