Matches in SemOpenAlex for { <https://semopenalex.org/work/W2617903873> ?p ?o ?g. }
- W2617903873 abstract "Pancreatic beta cells uniquely synthetize, store and release insulin. Specific molecular, functional as well as ultrastructural traits characterize their insulin secretion properties and survival phentoype. In this review we focus on human islet/beta cells, and describe the changes that occur in type 2 diabetes and could play roles in the disease as well as represent possible targets for therapeutical interventions. These include transcription factors, molecules involved in glucose metabolism and insulin granule handling. Quantitative and qualitative insulin release patterns and their changes in type 2 diabetes are also associated with ultrastructural features involving the insulin granules, the mitochondria and the endoplasmic reticulum." @default.
- W2617903873 created "2017-06-05" @default.
- W2617903873 creator A5000550995 @default.
- W2617903873 creator A5018890288 @default.
- W2617903873 creator A5029421295 @default.
- W2617903873 creator A5048913575 @default.
- W2617903873 creator A5054574491 @default.
- W2617903873 date "2017-05-23" @default.
- W2617903873 modified "2023-10-18" @default.
- W2617903873 title "Pancreatic Beta Cell Identity in Humans and the Role of Type 2 Diabetes" @default.
- W2617903873 cites W1012070930 @default.
- W2617903873 cites W1516023188 @default.
- W2617903873 cites W1555563535 @default.
- W2617903873 cites W1724200113 @default.
- W2617903873 cites W1920915588 @default.
- W2617903873 cites W1970011751 @default.
- W2617903873 cites W1973794425 @default.
- W2617903873 cites W1979892459 @default.
- W2617903873 cites W2004977380 @default.
- W2617903873 cites W2006007127 @default.
- W2617903873 cites W2006284854 @default.
- W2617903873 cites W2010089467 @default.
- W2617903873 cites W2014506057 @default.
- W2617903873 cites W2016895073 @default.
- W2617903873 cites W2023590295 @default.
- W2617903873 cites W2028325091 @default.
- W2617903873 cites W2030670787 @default.
- W2617903873 cites W2032045122 @default.
- W2617903873 cites W2045227229 @default.
- W2617903873 cites W2047792293 @default.
- W2617903873 cites W2052524549 @default.
- W2617903873 cites W2055791664 @default.
- W2617903873 cites W2056187976 @default.
- W2617903873 cites W2061574308 @default.
- W2617903873 cites W2063389425 @default.
- W2617903873 cites W2070457596 @default.
- W2617903873 cites W2073625634 @default.
- W2617903873 cites W2074549465 @default.
- W2617903873 cites W2076067223 @default.
- W2617903873 cites W2078000033 @default.
- W2617903873 cites W2081624003 @default.
- W2617903873 cites W2083850806 @default.
- W2617903873 cites W2089894176 @default.
- W2617903873 cites W2091536674 @default.
- W2617903873 cites W2095672168 @default.
- W2617903873 cites W2096273239 @default.
- W2617903873 cites W2099064596 @default.
- W2617903873 cites W2105565736 @default.
- W2617903873 cites W2108781675 @default.
- W2617903873 cites W2112383525 @default.
- W2617903873 cites W2113195064 @default.
- W2617903873 cites W2117574263 @default.
- W2617903873 cites W2122929112 @default.
- W2617903873 cites W2126700142 @default.
- W2617903873 cites W2129234537 @default.
- W2617903873 cites W2130890592 @default.
- W2617903873 cites W2132557269 @default.
- W2617903873 cites W2134971690 @default.
- W2617903873 cites W2135514753 @default.
- W2617903873 cites W2135902632 @default.
- W2617903873 cites W2137987484 @default.
- W2617903873 cites W2140188411 @default.
- W2617903873 cites W2142510033 @default.
- W2617903873 cites W2146561547 @default.
- W2617903873 cites W2153882592 @default.
- W2617903873 cites W2159205789 @default.
- W2617903873 cites W2159570963 @default.
- W2617903873 cites W2161466889 @default.
- W2617903873 cites W2167677329 @default.
- W2617903873 cites W2199891677 @default.
- W2617903873 cites W2209585205 @default.
- W2617903873 cites W2415858088 @default.
- W2617903873 cites W2460953575 @default.
- W2617903873 cites W2516174717 @default.
- W2617903873 cites W2518974058 @default.
- W2617903873 cites W2523369352 @default.
- W2617903873 cites W2523419694 @default.
- W2617903873 cites W2567510066 @default.
- W2617903873 cites W2592529564 @default.
- W2617903873 cites W2887036954 @default.
- W2617903873 doi "https://doi.org/10.3389/fcell.2017.00055" @default.
- W2617903873 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5440564" @default.
- W2617903873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28589121" @default.
- W2617903873 hasPublicationYear "2017" @default.
- W2617903873 type Work @default.
- W2617903873 sameAs 2617903873 @default.
- W2617903873 citedByCount "55" @default.
- W2617903873 countsByYear W26179038732016 @default.
- W2617903873 countsByYear W26179038732018 @default.
- W2617903873 countsByYear W26179038732019 @default.
- W2617903873 countsByYear W26179038732020 @default.
- W2617903873 countsByYear W26179038732021 @default.
- W2617903873 countsByYear W26179038732022 @default.
- W2617903873 countsByYear W26179038732023 @default.
- W2617903873 crossrefType "journal-article" @default.
- W2617903873 hasAuthorship W2617903873A5000550995 @default.
- W2617903873 hasAuthorship W2617903873A5018890288 @default.
- W2617903873 hasAuthorship W2617903873A5029421295 @default.
- W2617903873 hasAuthorship W2617903873A5048913575 @default.
- W2617903873 hasAuthorship W2617903873A5054574491 @default.