FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2617958165> ?p ?o ?g. }

• W2617958165 endingPage "1292" @default.
• W2617958165 startingPage "1286" @default.
• W2617958165 abstract "To analyze the impact of dynamic changes in inflammation on atherosclerosis in short-duration type 2 diabetes after multifactorial intervention.In this randomized controlled study, a total of 150 type 2 diabetes patients who had a mean age of 49.8±7.3years, 51% male, with disease duration <1year and without evidence of atherosclerosis were randomized into an intensive intervention group (IG), in which patients received multiple risk factors intervention by the special project team and tried to reach the pre-determined intervention goals, and a conventional group (CG), in which patients received standard diabetes care by the clinic doctor. All patients recieved intervention study for 7 years, then underwent a 3-year observational follow-up study. The primary endpoints were occurrence of subclinical atherosclerosis, defined as the intima-media thickness of the common carotid artery (CC-IMT)≥1.0mm or formation of atherosclerosis plaques, and the occurrence of cardiovascular events.68 patients in IG and 65 patients in CG completed the 10-year study. The cumulative incidence of subclinical atherosclerosis was 30.7% vs 57.3% (IG vs CG, HR 0.36, 95% CI 0.22-0.60, P<0.0001) and that of cardiovascular events was 12.0% vs 22.7% (IG vs CG, HR 0.46, 95% CI 0.21-0.98, P=0.0516). High sensitivity C-reactive protein (hs-CRP) reduction from baseline to the 10-year follow-up was -1.54mg/L (IG) and -0.67mg/L (CG) with difference (IG minus CG) of -0.87mg/L(95% CI -0.72 to -1.02, P=0.008) and the natural logarithm of serum amyloid A (SAA) reduction was -4.04 (IG) and -1.44 (CG) with difference (IG minus CG) of -2.60 (95% CI -2.30 to -2.90, P=0.002). The decrease in general score of inflammatory markers (combination of hs-CRP and SAA) was independently associated with subclinical atherosclerosis (OR=0.65, P=0.045) and cardiovascular events (OR=0.60, P=0.042).Dynamic changes in inflammation act as an important factor that affects the occurrence of atherosclerosis in type 2 diabetes patients. Multifactorial intensive intervention can reduce systemic low-grade inflammation and delay the occurrence of atherosclerosis in short-duration type 2 diabetes." @default.
• W2617958165 created "2017-06-05" @default.
• W2617958165 creator A5002251300 @default.
• W2617958165 creator A5003315806 @default.
• W2617958165 creator A5009017466 @default.
• W2617958165 creator A5025929154 @default.
• W2617958165 creator A5028940532 @default.
• W2617958165 creator A5048963632 @default.
• W2617958165 creator A5053704060 @default.
• W2617958165 creator A5064785596 @default.
• W2617958165 creator A5070729082 @default.
• W2617958165 creator A5079581260 @default.
• W2617958165 creator A5085140875 @default.
• W2617958165 creator A5088486032 @default.
• W2617958165 date "2017-08-01" @default.
• W2617958165 modified "2023-09-29" @default.
• W2617958165 title "Atherosclerosis associated with dynamic inflammation changes after multifactorial intervention in short-duration type 2 diabetes: A randomized, controlled, 10-year follow-up trial" @default.
• W2617958165 cites W1526927233 @default.
• W2617958165 cites W1553306905 @default.
• W2617958165 cites W172609984 @default.
• W2617958165 cites W1885726898 @default.
• W2617958165 cites W1975100968 @default.
• W2617958165 cites W2012811221 @default.
• W2617958165 cites W2016133202 @default.
• W2617958165 cites W2025086695 @default.
• W2617958165 cites W2035428538 @default.
• W2617958165 cites W2051916088 @default.
• W2617958165 cites W2080155990 @default.
• W2617958165 cites W2094325111 @default.
• W2617958165 cites W2097903089 @default.
• W2617958165 cites W2104350567 @default.
• W2617958165 cites W2118744821 @default.
• W2617958165 cites W2130266732 @default.
• W2617958165 cites W2139634859 @default.
• W2617958165 cites W2146392529 @default.
• W2617958165 cites W2151612951 @default.
• W2617958165 cites W2170271198 @default.
• W2617958165 cites W2171294019 @default.
• W2617958165 doi "https://doi.org/10.1016/j.jdiacomp.2017.05.008" @default.
• W2617958165 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28610945" @default.
• W2617958165 hasPublicationYear "2017" @default.
• W2617958165 type Work @default.
• W2617958165 sameAs 2617958165 @default.
• W2617958165 citedByCount "10" @default.
• W2617958165 countsByYear W26179581652018 @default.
• W2617958165 countsByYear W26179581652019 @default.
• W2617958165 countsByYear W26179581652020 @default.
• W2617958165 countsByYear W26179581652022 @default.
• W2617958165 countsByYear W26179581652023 @default.
• W2617958165 crossrefType "journal-article" @default.
• W2617958165 hasAuthorship W2617958165A5002251300 @default.
• W2617958165 hasAuthorship W2617958165A5003315806 @default.
• W2617958165 hasAuthorship W2617958165A5009017466 @default.
• W2617958165 hasAuthorship W2617958165A5025929154 @default.
• W2617958165 hasAuthorship W2617958165A5028940532 @default.
• W2617958165 hasAuthorship W2617958165A5048963632 @default.
• W2617958165 hasAuthorship W2617958165A5053704060 @default.
• W2617958165 hasAuthorship W2617958165A5064785596 @default.
• W2617958165 hasAuthorship W2617958165A5070729082 @default.
• W2617958165 hasAuthorship W2617958165A5079581260 @default.
• W2617958165 hasAuthorship W2617958165A5085140875 @default.
• W2617958165 hasAuthorship W2617958165A5088486032 @default.
• W2617958165 hasConcept C113280763 @default.
• W2617958165 hasConcept C120665830 @default.
• W2617958165 hasConcept C121332964 @default.
• W2617958165 hasConcept C126322002 @default.
• W2617958165 hasConcept C134018914 @default.
• W2617958165 hasConcept C164705383 @default.
• W2617958165 hasConcept C168563851 @default.
• W2617958165 hasConcept C23131810 @default.
• W2617958165 hasConcept C2776914184 @default.
• W2617958165 hasConcept C2777180221 @default.
• W2617958165 hasConcept C555293320 @default.
• W2617958165 hasConcept C61511704 @default.
• W2617958165 hasConcept C71924100 @default.
• W2617958165 hasConcept C90924648 @default.
• W2617958165 hasConceptScore W2617958165C113280763 @default.
• W2617958165 hasConceptScore W2617958165C120665830 @default.
• W2617958165 hasConceptScore W2617958165C121332964 @default.
• W2617958165 hasConceptScore W2617958165C126322002 @default.
• W2617958165 hasConceptScore W2617958165C134018914 @default.
• W2617958165 hasConceptScore W2617958165C164705383 @default.
• W2617958165 hasConceptScore W2617958165C168563851 @default.
• W2617958165 hasConceptScore W2617958165C23131810 @default.
• W2617958165 hasConceptScore W2617958165C2776914184 @default.
• W2617958165 hasConceptScore W2617958165C2777180221 @default.
• W2617958165 hasConceptScore W2617958165C555293320 @default.
• W2617958165 hasConceptScore W2617958165C61511704 @default.
• W2617958165 hasConceptScore W2617958165C71924100 @default.
• W2617958165 hasConceptScore W2617958165C90924648 @default.
• W2617958165 hasIssue "8" @default.
• W2617958165 hasLocation W26179581651 @default.
• W2617958165 hasLocation W26179581652 @default.
• W2617958165 hasOpenAccess W2617958165 @default.
• W2617958165 hasPrimaryLocation W26179581651 @default.
• W2617958165 hasRelatedWork W1563850031 @default.
• W2617958165 hasRelatedWork W1967947002 @default.
• W2617958165 hasRelatedWork W1978168647 @default.

• next