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- W2618320451 abstract "<b><i>Background/Aims:</i></b> In adults, lower vitamin D has been associated with increased albuminuria. This association has not been extensively studied in youth with or without type 1 diabetes. <b><i>Methods:</i></b> We examined the cross-sectional association between vitamin D and albuminuria (urine albumin to creatinine ratio ≥30 mg/g) in 8,789 participants of the National Health and Nutrition Survey 2001–2006 (NHANES), who were 6–19 years old. Further, we examined the association between vitamin D and albuminuria in 938 participants from the SEARCH Nutritional Ancillary Study (SNAS), a longitudinal cohort of youth with type 1 diabetes. <b><i>Results:</i></b> Of the NHANES participants, 5.3, 19.5, and 53.7% had vitamin D levels <30, 50 and 80 nmol/L, respectively. Albuminuria was present in 12.8% and was more common in younger children, females, non-Hispanic whites, non-obese children, and children with hypertension. After adjustments, there was no association between vitamin D and albuminuria. Among the SNAS participants with type 1 diabetes, we also found no association between baseline vitamin D and subsequent albuminuria in unadjusted or adjusted analyses. <b><i>Conclusion:</i></b> We did not find an association between serum vitamin D and albuminuria in either non-diabetic youth or those with type 1 diabetes. Further research is needed to more fully understand this relationship." @default.
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- W2618320451 date "2017-01-01" @default.
- W2618320451 modified "2023-09-25" @default.
- W2618320451 title "Vitamin D and Albuminuria in Youth with and without Type 1 Diabetes" @default.
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- W2618320451 doi "https://doi.org/10.1159/000475711" @default.
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