Matches in SemOpenAlex for { <https://semopenalex.org/work/W2619380285> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2619380285 endingPage "5" @default.
- W2619380285 startingPage "1" @default.
- W2619380285 abstract "Background and Objective . Dopamine dysfunction is known to be associated with attention deficit hyperactivity disorder (ADHD). Dopamine D4 receptor gene (DRD4) is one of the important genes in this pathway. This study intended to investigate the variable number of tandem repeats (VNTR) in exon 3 of the DRD4 gene in Iranian children and adolescents. Materials and Methods . In this study, 130 children with ADHD, aged 6–14 years, and 130 healthy children, within the same age range, were enrolled. All children were selected from northwest of Iran which have Caucasian ethnic background and are of a Turkic ethnic group. VNTR polymorphisms of the DRD4 gene were evaluated by PCR using exon 3-specific primers followed by agarose gel electrophoresis. Findings . The Hardy-Weinberg principle and Chi-square test showed a significant difference in 4-repetition (4R) alleles between the ADHD (76.2%) and control (53.8%) groups (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mi>p</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle=italic>0.004</mml:mn></mml:math>; <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:msup><mml:mrow><mml:mi>X</mml:mi></mml:mrow><mml:mrow><mml:mn fontstyle=italic>2</mml:mn></mml:mrow></mml:msup><mml:mo>=</mml:mo><mml:mn fontstyle=italic>17.39</mml:mn></mml:math>; <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mi mathvariant=normal>d</mml:mi><mml:mi mathvariant=normal>f</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle=italic>5</mml:mn></mml:math>). The least percentage of repetition alleles in both groups was 2R. Conclusion . There is a significant correlation between the 4R alleles of DRD4 and ADHD in the northwest of Iran." @default.
- W2619380285 created "2017-06-05" @default.
- W2619380285 creator A5005363973 @default.
- W2619380285 creator A5014927498 @default.
- W2619380285 creator A5014964815 @default.
- W2619380285 creator A5026313819 @default.
- W2619380285 creator A5031218818 @default.
- W2619380285 creator A5087028683 @default.
- W2619380285 date "2017-05-24" @default.
- W2619380285 modified "2023-10-16" @default.
- W2619380285 title "DRD4 Gene Polymorphisms as a Risk Factor for Children with Attention Deficit Hyperactivity Disorder in Iranian Population" @default.
- W2619380285 cites W1482696263 @default.
- W2619380285 cites W1509504473 @default.
- W2619380285 cites W1514493379 @default.
- W2619380285 cites W164878589 @default.
- W2619380285 cites W1780178221 @default.
- W2619380285 cites W1911963278 @default.
- W2619380285 cites W1965930842 @default.
- W2619380285 cites W1973785128 @default.
- W2619380285 cites W1995157367 @default.
- W2619380285 cites W1996266106 @default.
- W2619380285 cites W1998670974 @default.
- W2619380285 cites W2026395566 @default.
- W2619380285 cites W2053529553 @default.
- W2619380285 cites W2080474882 @default.
- W2619380285 cites W2085186602 @default.
- W2619380285 cites W2086710797 @default.
- W2619380285 cites W2099230513 @default.
- W2619380285 cites W2101549867 @default.
- W2619380285 cites W2106718396 @default.
- W2619380285 cites W2110483804 @default.
- W2619380285 cites W2121775947 @default.
- W2619380285 cites W2125049636 @default.
- W2619380285 cites W2129527517 @default.
- W2619380285 cites W2129793824 @default.
- W2619380285 cites W2131208794 @default.
- W2619380285 cites W2162012775 @default.
- W2619380285 cites W2186549343 @default.
- W2619380285 cites W4233075478 @default.
- W2619380285 doi "https://doi.org/10.1155/2017/2494537" @default.
- W2619380285 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5463114" @default.
- W2619380285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28630890" @default.
- W2619380285 hasPublicationYear "2017" @default.
- W2619380285 type Work @default.
- W2619380285 sameAs 2619380285 @default.
- W2619380285 citedByCount "5" @default.
- W2619380285 countsByYear W26193802852021 @default.
- W2619380285 countsByYear W26193802852022 @default.
- W2619380285 crossrefType "journal-article" @default.
- W2619380285 hasAuthorship W2619380285A5005363973 @default.
- W2619380285 hasAuthorship W2619380285A5014927498 @default.
- W2619380285 hasAuthorship W2619380285A5014964815 @default.
- W2619380285 hasAuthorship W2619380285A5026313819 @default.
- W2619380285 hasAuthorship W2619380285A5031218818 @default.
- W2619380285 hasAuthorship W2619380285A5087028683 @default.
- W2619380285 hasBestOaLocation W26193802851 @default.
- W2619380285 hasConcept C11413529 @default.
- W2619380285 hasConcept C2908647359 @default.
- W2619380285 hasConcept C41008148 @default.
- W2619380285 hasConcept C71924100 @default.
- W2619380285 hasConcept C99454951 @default.
- W2619380285 hasConceptScore W2619380285C11413529 @default.
- W2619380285 hasConceptScore W2619380285C2908647359 @default.
- W2619380285 hasConceptScore W2619380285C41008148 @default.
- W2619380285 hasConceptScore W2619380285C71924100 @default.
- W2619380285 hasConceptScore W2619380285C99454951 @default.
- W2619380285 hasLocation W26193802851 @default.
- W2619380285 hasLocation W26193802852 @default.
- W2619380285 hasLocation W26193802853 @default.
- W2619380285 hasLocation W26193802854 @default.
- W2619380285 hasOpenAccess W2619380285 @default.
- W2619380285 hasPrimaryLocation W26193802851 @default.
- W2619380285 hasRelatedWork W1489783725 @default.
- W2619380285 hasRelatedWork W1506200166 @default.
- W2619380285 hasRelatedWork W2039318446 @default.
- W2619380285 hasRelatedWork W2048182022 @default.
- W2619380285 hasRelatedWork W2080531066 @default.
- W2619380285 hasRelatedWork W2604872355 @default.
- W2619380285 hasRelatedWork W2748952813 @default.
- W2619380285 hasRelatedWork W2899084033 @default.
- W2619380285 hasRelatedWork W3032375762 @default.
- W2619380285 hasRelatedWork W3108674512 @default.
- W2619380285 hasVolume "2017" @default.
- W2619380285 isParatext "false" @default.
- W2619380285 isRetracted "false" @default.
- W2619380285 magId "2619380285" @default.
- W2619380285 workType "article" @default.