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• W2619639234 abstract "Incidence of ischemic stroke and transient ischemic attack in young adults is rising. However, etiology remains unknown in 30-40% of these patients when current classification systems designed for the elderly are used. Our aim was to identify risk factors according to a pediatric approach, which might lead to both better identification of risk factors and provide a stepping stone for the understanding of disease mechanism, particularly in patients currently classified as unknown etiology. Risk factors of 656 young stroke patients (aged 18-50) of the FUTURE study were categorized according to the International Pediatric Stroke Study (IPSS), with stratification on gender, age and stroke of unknown etiology. Categorization of risk factors into ≥1 IPSS category was possible in 94% of young stroke patients. Chronic systemic conditions were more present in patients aged <35 compared to patients ≥35 (32.6% vs. 15.6%, p < 0.05). Among 226 patients classified as stroke of unknown etiology using TOAST, we found risk factors in 199 patients (88%) with the IPSS approach. We identified multiple risk factors linked to other mechanisms of stroke in the young than in the elderly . This can be a valuable starting point to develop an etiologic classification system specifically designed for young stroke patients." @default.
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• W2619639234 date "2017-05-23" @default.
• W2619639234 modified "2023-10-18" @default.
• W2619639234 title "Risk factors and mechanisms of stroke in young adults: The FUTURE study" @default.
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• W2619639234 doi "https://doi.org/10.1177/0271678x17707138" @default.
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