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• W2619784037 abstract "Arbuscular mycorrhizal fungi (AMF) are widespread root symbionts that perform important ecological services, such as improving plant nutrient and water acquisition. Some AMF from the Gigasporaceae family host a population of endobacteria, Candidatus Glomeribacter gigasporarum (Cagg). The analysis of the Cagg genome identified six putative toxin–antitoxin modules (TAs), consisting of pairs of stable toxins and unstable antitoxins that affect diverse physiological functions. Sequence analysis suggested that these TA modules were acquired by horizontal transfer. Gene expression patterns of two TAs (yoeB/yefM and chpB/chpS) changed during the fungal life cycle, with the expression during the pre-symbiotic phase higher than during the symbiosis with the plant host. The heterologous expression in Escherichia coli demonstrated the functionality only for the YoeB–YefM pair. On the basis of these observations, we speculate that TA modules might help Cagg adapt to its intracellular habitat, coordinating its proliferation with the physiological state of the AMF host." @default.
• W2619784037 created "2017-06-05" @default.
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• W2619784037 date "2017-05-26" @default.
• W2619784037 modified "2023-10-01" @default.
• W2619784037 title "The endobacterium of an arbuscular mycorrhizal fungus modulates the expression of its toxin–antitoxin systems during the life cycle of its host" @default.
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• W2619784037 doi "https://doi.org/10.1038/ismej.2017.84" @default.
• W2619784037 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5607366" @default.
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