FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2620051567> ?p ?o ?g. }

• W2620051567 endingPage "918" @default.
• W2620051567 startingPage "910" @default.
• W2620051567 abstract "Background: Multiple sclerosis (MS) is an autoimmune disease for which auto-antibodies fully validated as diagnostic and prognostic biomarkers are widely desired. Recently, an immunoreactivity against the inward rectifying potassium channel 4.1 (KIR4.1) has been reported in a large proportion of a group of MS patients, with amino acids 83–120 being the major epitope. Moreover, a strong correlation between anti-KIR4.1 83–120 and anti-full-length-protein auto-antibodies titer was reported. However, this finding received limited confirmation. Objective: Validation of the diagnostic potential of anti-KIR4.1 83–120 antibodies in 78 MS patients, 64 healthy blood donors, and 42 individuals with other neurological diseases. Methods: Analysis of anti-KIR4.1 83–120 antibodies by enzyme-linked immunosorbent assay (ELISA) using a mouse antiserum we produced as a new ELISA reliability control. Additionally, evaluation of reactivity against 293-T cells transiently transfected with full-length KIR4.1 by flow cytometry. Results: We found antibodies to KIR4.1 83–120 only in 13 out of 78 (16.6%) MS patients; among these, only 2 were positive for anti-full-length KIR4.1 antibodies. Conclusion: Employing a new reliability control and a new cytofluorometric assay, we cannot support anti-KIR4.1 83–120 auto-antibodies as a reliable biomarker in MS." @default.
• W2620051567 created "2017-06-05" @default.
• W2620051567 creator A5011515853 @default.
• W2620051567 creator A5015063200 @default.
• W2620051567 creator A5024633714 @default.
• W2620051567 creator A5031084295 @default.
• W2620051567 creator A5041217228 @default.
• W2620051567 creator A5053649701 @default.
• W2620051567 creator A5056034610 @default.
• W2620051567 creator A5084634930 @default.
• W2620051567 creator A5088944331 @default.
• W2620051567 date "2017-05-26" @default.
• W2620051567 modified "2023-10-01" @default.
• W2620051567 title "Low reliability of anti-KIR4.1_83–120 peptide auto-antibodies in multiple sclerosis patients" @default.
• W2620051567 cites W1516459565 @default.
• W2620051567 cites W1970626055 @default.
• W2620051567 cites W1975140208 @default.
• W2620051567 cites W1976286607 @default.
• W2620051567 cites W1993868490 @default.
• W2620051567 cites W2007654857 @default.
• W2620051567 cites W2009308901 @default.
• W2620051567 cites W2042855455 @default.
• W2620051567 cites W2046451999 @default.
• W2620051567 cites W2059577188 @default.
• W2620051567 cites W2068200390 @default.
• W2620051567 cites W2102651340 @default.
• W2620051567 cites W2105490558 @default.
• W2620051567 cites W2120238028 @default.
• W2620051567 cites W2122542523 @default.
• W2620051567 cites W2129134090 @default.
• W2620051567 cites W2139113477 @default.
• W2620051567 cites W2141111992 @default.
• W2620051567 cites W2157161374 @default.
• W2620051567 cites W2160872052 @default.
• W2620051567 cites W2337239559 @default.
• W2620051567 cites W2338933683 @default.
• W2620051567 cites W2483107574 @default.
• W2620051567 cites W2524504797 @default.
• W2620051567 cites W295908243 @default.
• W2620051567 cites W2106609579 @default.
• W2620051567 doi "https://doi.org/10.1177/1352458517711275" @default.
• W2620051567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28548026" @default.
• W2620051567 hasPublicationYear "2017" @default.
• W2620051567 type Work @default.
• W2620051567 sameAs 2620051567 @default.
• W2620051567 citedByCount "5" @default.
• W2620051567 countsByYear W26200515672017 @default.
• W2620051567 countsByYear W26200515672019 @default.
• W2620051567 countsByYear W26200515672020 @default.
• W2620051567 countsByYear W26200515672022 @default.
• W2620051567 crossrefType "journal-article" @default.
• W2620051567 hasAuthorship W2620051567A5011515853 @default.
• W2620051567 hasAuthorship W2620051567A5015063200 @default.
• W2620051567 hasAuthorship W2620051567A5024633714 @default.
• W2620051567 hasAuthorship W2620051567A5031084295 @default.
• W2620051567 hasAuthorship W2620051567A5041217228 @default.
• W2620051567 hasAuthorship W2620051567A5053649701 @default.
• W2620051567 hasAuthorship W2620051567A5056034610 @default.
• W2620051567 hasAuthorship W2620051567A5084634930 @default.
• W2620051567 hasAuthorship W2620051567A5088944331 @default.
• W2620051567 hasConcept C126322002 @default.
• W2620051567 hasConcept C159654299 @default.
• W2620051567 hasConcept C163764329 @default.
• W2620051567 hasConcept C195616568 @default.
• W2620051567 hasConcept C203014093 @default.
• W2620051567 hasConcept C2780640218 @default.
• W2620051567 hasConcept C2781197716 @default.
• W2620051567 hasConcept C32611913 @default.
• W2620051567 hasConcept C553184892 @default.
• W2620051567 hasConcept C55493867 @default.
• W2620051567 hasConcept C71924100 @default.
• W2620051567 hasConcept C86803240 @default.
• W2620051567 hasConceptScore W2620051567C126322002 @default.
• W2620051567 hasConceptScore W2620051567C159654299 @default.
• W2620051567 hasConceptScore W2620051567C163764329 @default.
• W2620051567 hasConceptScore W2620051567C195616568 @default.
• W2620051567 hasConceptScore W2620051567C203014093 @default.
• W2620051567 hasConceptScore W2620051567C2780640218 @default.
• W2620051567 hasConceptScore W2620051567C2781197716 @default.
• W2620051567 hasConceptScore W2620051567C32611913 @default.
• W2620051567 hasConceptScore W2620051567C553184892 @default.
• W2620051567 hasConceptScore W2620051567C55493867 @default.
• W2620051567 hasConceptScore W2620051567C71924100 @default.
• W2620051567 hasConceptScore W2620051567C86803240 @default.
• W2620051567 hasIssue "7" @default.
• W2620051567 hasLocation W26200515671 @default.
• W2620051567 hasLocation W26200515672 @default.
• W2620051567 hasOpenAccess W2620051567 @default.
• W2620051567 hasPrimaryLocation W26200515671 @default.
• W2620051567 hasRelatedWork W1796990215 @default.
• W2620051567 hasRelatedWork W2034906732 @default.
• W2620051567 hasRelatedWork W2045507082 @default.
• W2620051567 hasRelatedWork W2047056828 @default.
• W2620051567 hasRelatedWork W2079434831 @default.
• W2620051567 hasRelatedWork W2101875571 @default.
• W2620051567 hasRelatedWork W2161246929 @default.
• W2620051567 hasRelatedWork W2494708045 @default.
• W2620051567 hasRelatedWork W2994706881 @default.

• next