FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2620239524> ?p ?o ?g. }

• W2620239524 endingPage "523" @default.
• W2620239524 startingPage "518" @default.
• W2620239524 abstract "HomeCirculation ResearchVol. 28, No. 5Response of Pial Precapillary Vessels to Changes in Arterial Carbon Dioxide Tension Free AccessResearch ArticlePDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessResearch ArticlePDF/EPUBResponse of Pial Precapillary Vessels to Changes in Arterial Carbon Dioxide Tension A. JARRELL RAPER, HERMES A. KONTOS and JOHN L. PATTERSONJr. A. JARRELL RAPERA. JARRELL RAPER Department of Medicine, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia 23219 Search for more papers by this author , HERMES A. KONTOSHERMES A. KONTOS Department of Medicine, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia 23219 Search for more papers by this author and JOHN L. PATTERSONJr.JOHN L. PATTERSONJr. Department of Medicine, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia 23219 Search for more papers by this author Originally published1 May 1971https://doi.org/10.1161/01.RES.28.5.518Circulation Research. 1971;28:518–523AbstractA quantitative study of responses of pial precapillary vessels to changes in arterial blood carbon dioxide tension was made in anesthetized cats. All vessels examined ranging in diameter from 13 to 90μ responded to hypercapnia with increases in diameter and to hypocapnia with decreases in diameter. The onset of the response to hypercapnia was earlier, its speed was faster, and its magnitude greater with higher concentrations of CO2. In response to the same increase in arterial blood PCO2, smaller vessels (13 to 40μ) increased in diameter by 47.7 ± 10.8% of the control value while the increase in diameter of larger vessels (41 to 90μ) was significantly lower and equal to 29.5 ± 6.3% of the control value. In the steady state the relation between pial vessel diameter expressed as percent of the control value (Y) and arterial blood PCO2 (X) was given by the equation Y = 53.07 + 1.587 X – 0.00715 X2. The relatively large magnitude of the response of pial arteries and arterioles to CO2 and the fact that it was dependent on vessel size show that there must be significant readjustments in the pressure gradients in these vessels when CO2 tension is changed. Previous Back to top Next FiguresReferencesRelatedDetailsCited By Yao J, Yang H, Wang J, Liang Z, Talavage T, Tamer G, Jang I and Tong Y (2021) A novel method of quantifying hemodynamic delays to improve hemodynamic response, and CVR estimates in CO2 challenge fMRI, Journal of Cerebral Blood Flow & Metabolism, 10.1177/0271678X20978582, 41:8, (1886-1898), Online publication date: 1-Aug-2021. Bullock T, Giesbrecht B, Beaudin A, Goodyear B and Poulin M (2021) Effects of changes in end‐tidal PO 2 and PCO 2 on neural responses during rest and sustained attention , Physiological Reports, 10.14814/phy2.15106, 9:21, Online publication date: 1-Nov-2021. Takuwa H, Matsuura T, Obata T, Kawaguchi H, Kanno I and Ito H (2012) Hemodynamic changes during somatosensory stimulation in awake and isoflurane-anesthetized mice measured by laser-Doppler flowmetry, Brain Research, 10.1016/j.brainres.2012.06.049, 1472, (107-112), Online publication date: 1-Sep-2012. Piechnik S, Chiarelli P and Jezzard P (2008) Modelling vascular reactivity to investigate the basis of the relationship between cerebral blood volume and flow under CO2 manipulation, NeuroImage, 10.1016/j.neuroimage.2007.08.022, 39:1, (107-118), Online publication date: 1-Jan-2008. Venkataraman S, Hudson C, Fisher J, Rodrigues L, Mardimae A and Flanagan J (2008) Retinal arteriolar and capillary vascular reactivity in response to isoxic hypercapnia, Experimental Eye Research, 10.1016/j.exer.2008.08.020, 87:6, (535-542), Online publication date: 1-Dec-2008. Hochman D (2006) Optical Imaging Encyclopedia of Language & Linguistics, 10.1016/B0-08-044854-2/02401-9, (55-60), . Venkataraman S, Hudson C, Fisher J and Flanagan J (2006) Novel methodology to comprehensively assess retinal arteriolar vascular reactivity to hypercapnia, Microvascular Research, 10.1016/j.mvr.2006.06.002, 72:3, (101-107), Online publication date: 1-Nov-2006. Ito H, Ibaraki M, Kanno I, Fukuda H and Miura S (2005) Changes in the Arterial Fraction of Human Cerebral Blood Volume during Hypercapnia and Hypocapnia Measured by Positron Emission Tomography, Journal of Cerebral Blood Flow & Metabolism, 10.1038/sj.jcbfm.9600076, 25:7, (852-857), Online publication date: 1-Jul-2005. Ito H, Kanno I and Fukuda H (2009) Human cerebral circulation: positron emission tomography studies, Annals of Nuclear Medicine, 10.1007/BF03027383, 19:2, (65-74), Online publication date: 1-Apr-2005. Venkataraman S, Hudson C, Fisher J and Flanagan J (2005) The impact of hypercapnia on retinal capillary blood flow assessed by scanning laser Doppler flowmetry, Microvascular Research, 10.1016/j.mvr.2005.02.003, 69:3, (149-155), Online publication date: 1-May-2005. Ito H, Kanno I, Ibaraki M, Hatazawa J and Miura S (2016) Changes in Human Cerebral Blood Flow and Cerebral Blood Volume during Hypercapnia and Hypocapnia Measured by Positron Emission Tomography, Journal of Cerebral Blood Flow & Metabolism, 10.1097/01.WCB.0000067721.64998.F5, 23:6, (665-670), Online publication date: 1-Jun-2003. Ito H, Kanno I, Ibaraki M and Hatazawa J (2016) Effect of Aging on Cerebral Vascular Response to Paco 2 Changes in Humans as Measured by Positron Emission Tomography , Journal of Cerebral Blood Flow & Metabolism, 10.1097/00004647-200208000-00011, 22:8, (997-1003), Online publication date: 1-Aug-2002. De Visscher G, van Rossem K, Van Reempts J, Borgers M, Flameng W and Reneman R (2002) Cerebral blood flow assessment with indocyanine green bolus transit detection by near-infrared spectroscopy in the rat, Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 10.1016/S1095-6433(01)00533-5, 132:1, (87-95), Online publication date: 1-May-2002. Ito H, Yokoyama I, Iida H, Kinoshita T, Hatazawa J, Shimosegawa E, Okudera T and Kanno I (2016) Regional Differences in Cerebral Vascular Response to P a co 2 Changes in Humans Measured by Positron Emission Tomography , Journal of Cerebral Blood Flow & Metabolism, 10.1097/00004647-200008000-00011, 20:8, (1264-1270), Online publication date: 1-Aug-2000. Yoon S, Zuccarello M and Rapoport R (2000) Reversal of hypercapnia induces KATP channel and NO-independent constriction of basilar artery in rabbits with acute metabolic alkalosis, General Pharmacology: The Vascular System, 10.1016/S0306-3623(02)00111-8, 35:6, (325-332), Online publication date: 1-Dec-2000. Boero J, Ascher J, Arregui A, Rovainen C and Woolsey T (1999) Increased brain capillaries in chronic hypoxia, Journal of Applied Physiology, 10.1152/jappl.1999.86.4.1211, 86:4, (1211-1219), Online publication date: 1-Apr-1999. Ursino M and Lodi C (1998) Interaction among autoregulation, CO 2 reactivity, and intracranial pressure: a mathematical model , American Journal of Physiology-Heart and Circulatory Physiology, 10.1152/ajpheart.1998.274.5.H1715, 274:5, (H1715-H1728), Online publication date: 1-May-1998. Djurberg H, Seed R, Price Evans D, Brohi F, Pyper D, Tjan G and Al Moutaery K (1998) Lack of effect of CO2 on cerebral arterial diameter in man, Journal of Clinical Anesthesia, 10.1016/S0952-8180(98)00107-X, 10:8, (646-651), Online publication date: 1-Dec-1998. Harkin C, Schmeling W, Kampine J and Farber N (1997) The effects of hyper- and hypocarbia on intraparenchymal arterioles in rat brain slices, NeuroReport, 10.1097/00001756-199705260-00010, 8:8, (1841-1844), Online publication date: 1-May-1997. Ludbrook G, Upton R, Grant C and Gray E (2019) Cerebral Effects of Propofol following Bolus Administration in Sheep, Anaesthesia and Intensive Care, 10.1177/0310057X9602400105, 24:1, (26-31), Online publication date: 1-Feb-1996. Keyeux A, Ochrymowicz-Bemelmans D and Charlier A (2016) Induced Response to Hypercapnia in the Two-Compartment Total Cerebral Blood Volume: Influence on Brain Vascular Reserve and Flow Efficiency, Journal of Cerebral Blood Flow & Metabolism, 10.1038/jcbfm.1995.139, 15:6, (1121-1131), Online publication date: 1-Nov-1995. Chen J, Wei L, Bereczki D, Hans F, Otsuka T, Acuff V, Ghersi-Egea J, Patlak C and Fenstermacher J (2016) Nicotine Raises the Influx of Permeable Solutes across the Rat Blood—Brain Barrier with Little or No Capillary Recruitment, Journal of Cerebral Blood Flow & Metabolism, 10.1038/jcbfm.1995.85, 15:4, (687-698), Online publication date: 1-Jul-1995. KUMANO H, FURUYA H, YOMOSA H, NAGAHATA T, OKUDA T and SAKAKI T (1994) Response of pial vessel diameter and regional cerebral blood flow to CO2 during midazolam administration in cats, Acta Anaesthesiologica Scandinavica, 10.1111/j.1399-6576.1994.tb03986.x, 38:7, (729-733), Online publication date: 1-Oct-1994. Wang Q, Pelligrino D, Paulson O and Lassen N (1994) Comparison of the effects of NG-nitro-L-arginine and indomethacin on the hypercapnic cerebral blood flow increase in rats, Brain Research, 10.1016/0006-8993(94)90152-X, 641:2, (257-264), Online publication date: 1-Apr-1994. Wei L, Otsuka T, Acuff V, Bereczki D, Pettigrew K, Patlak C and Fenstermacher J (2016) The Velocities of Red Cell and Plasma Flows through Parenchymal Microvessels of Rat Brain are Decreased by Pentobarbital, Journal of Cerebral Blood Flow & Metabolism, 10.1038/jcbfm.1993.63, 13:3, (487-497), Online publication date: 1-May-1993. Bereczki D, Wei L, Otsuka T, Acuff V, Pettigrew K, Patlak C and Fenstermacher J (2016) Hypoxia Increases Velocity of Blood Flow through Parenchymal Microvascular Systems in Rat Brain, Journal of Cerebral Blood Flow & Metabolism, 10.1038/jcbfm.1993.62, 13:3, (475-486), Online publication date: 1-May-1993. Artru A (1993) Cerebral Blood Flow: Physiology and Pharmacology Anesthesia and the Central Nervous System, 10.1007/978-94-011-1610-7_1, (1-15), . Ludbrook G, Helps S and Gorman D (2016) Cerebral Blood Flow Response to Increases in Arterial CO 2 Tension during Alfentanil Anesthesia in the Rabbit , Journal of Cerebral Blood Flow & Metabolism, 10.1038/jcbfm.1992.73, 12:3, (529-532), Online publication date: 1-May-1992. Kawamura S and Yasui N (1992) Observation of the blood-brain barrier function and vasomotor response in rat microcirculation using intravital fluorescence microscopy, Experimental Neurology, 10.1016/0014-4886(92)90133-B, 117:3, (247-253), Online publication date: 1-Sep-1992. Yoshimoto S, Ishizaki Y, Sasaki T and Murota S (1991) Effect of carbon dioxide and oxygen on endothelin production by cultured porcine cerebral endothelial cells., Stroke, 22:3, (378-383), Online publication date: 1-Mar-1991. Simpson R and Phillis J (1991) Adenosine deaminase reduces hypoxic and hypercapnic dilatation of rat pial arterioles: evidence for mediation by adenosine, Brain Research, 10.1016/0006-8993(91)90839-N, 553:2, (305-308), Online publication date: 1-Jul-1991. Atkinson J, Anderson R and Sundt T (1990) The effect of carbon dioxide on the diameter of brain capillaries, Brain Research, 10.1016/0006-8993(90)91046-J, 517:1-2, (333-340), Online publication date: 1-May-1990. Morii S, Ngai A and Winn H (2016) Reactivity of Rat Pial Arterioles and Venules to Adenosine and Carbon Dioxide: With Detailed Description of the Closed Cranial Window Technique in Rats, Journal of Cerebral Blood Flow & Metabolism, 10.1038/jcbfm.1986.5, 6:1, (34-41), Online publication date: 1-Feb-1986. Niemeyer G and Steinberg R (1984) Differential effects of pCO2 and pH on the ERG and light peak of the perfused cat eye, Vision Research, 10.1016/0042-6989(84)90131-7, 24:3, (275-280), Online publication date: 1-Jan-1984. McCulloch J and Edvinsson L (2016) Cerebrovascular Smooth Muscle Reactivity: A Critical Appraisal of in vitro and in situ Techniques , Journal of Cerebral Blood Flow & Metabolism, 10.1038/jcbfm.1984.21, 4:2, (129-139), Online publication date: 1-Jun-1984. Heistad D and Kontos H (1983) Cerebral Circulation Comprehensive Physiology, 10.1002/cphy.cp020305, (137-182), Online publication date: 1-Dec-1983. Chin W, Imai S, Nakano U, Takeda K, Tamatsu H and Ushijima T (2012) Effects of drugs on the cerebral circulation of the dog in relation to the cerebral oxygen consumption, British Journal of Pharmacology, 10.1111/j.1476-5381.1983.tb10534.x, 79:4, (897-906), Online publication date: 1-Aug-1983. Auer L, Trummer U and Johansson B (1981) Alpha-adrenoreceptor antagonists and pial vessel diameter during hypercapnia and hemorrhagic hypotension in the cat., Stroke, 12:6, (847-851), Online publication date: 1-Nov-1981. Pawlik G, Rackl A and Bing R (1981) Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study, Brain Research, 10.1016/0006-8993(81)90619-3, 208:1, (35-58), Online publication date: 1-Mar-1981. Sadoshima S, Fujishima M, Tamaki K, Nakatomi Y, Ishitsuka T, Ogata J and Omae T (1980) Response of cortical and pial arteries to changes of arterial CO2 tension in rats — a morphometric study, Brain Research, 10.1016/0006-8993(80)90011-6, 189:1, (115-120), Online publication date: 1-May-1980. Gregory P, Boisvert D and Harper A (1980) Adenosine response on pial arteries, influence of CO2 and blood pressure, Pfl�gers Archiv European Journal of Physiology, 10.1007/BF00584207, 386:2, (187-192), . Oishi M, Gotoh F, Toyoda M, Seki T, Takeoka T, Takagi S and Niimi T (1979) Modification of cerebrovascular CO2 reactivity by inhibition of dopamine beta-hydroxylase., Stroke, 10:4, (407-411), Online publication date: 1-Jul-1979. Busija D and Heistad D (1984) Factors involved in the physiological regulation of the cerebral circulation Reviews of Physiology, Biochemistry and Pharmacology, Volume 86, 10.1007/BFb0027696, (161-211), . Wiegman D, Miller F and Harris P (1979) Modification of α-adrenergic responses of small arteries by altered PCO2 and pH, European Journal of Pharmacology, 10.1016/0014-2999(79)90493-X, 57:4, (307-315), Online publication date: 1-Aug-1979. Wei E, Kontos H and Patterson J (1978) Vasoconstrictor effect of angiotensin on pial arteries., Stroke, 9:5, (487-489), Online publication date: 1-Sep-1978.Cook B, Granger H, Granger D, Taylor A and Smith E (1978) Metabolic profiles of canine cerebrovascular tree: a histochemical study., Stroke, 9:2, (165-168), Online publication date: 1-Mar-1978. Oishi M, Niimi T, Takagi S, Takeoka T, Seki T, Toyoda M and Gotoh F (1978) Chemical control of cerebral circulation, Journal of the Neurological Sciences, 10.1016/0022-510X(78)90047-3, 36:3, (403-410), Online publication date: 1-May-1978. Greenberg J, Reivich M and Noordergraaf A (1978) A model of cerebral blood flow control in hypercapnia, Annals of Biomedical Engineering, 10.1007/BF02584551, 6:4, (453-491), Online publication date: 1-Dec-1978. Hayakawa T, Waltz A and Hansen T (1977) Relationships among intracranial pressure, blood pressure, and superficial cerebral vasculature after experimental occlusion of one middle cerebral artery., Stroke, 8:4, (426-432), Online publication date: 1-Jul-1977. Bates D, Weinshilboum R, Jean Campbell R and Sundt T (1977) The effect of lesions in the locus coeruleus on the physiological responses of the cerebral blood vessels in cats, Brain Research, 10.1016/0006-8993(77)90068-3, 136:3, (431-443), Online publication date: 1-Nov-1977. Pittman R and Duling B (1977) Effects of altered carbon dioxide tension on hemoglobin oxygenation in hamster cheek pouch microvessels, Microvascular Research, 10.1016/0026-2862(77)90086-3, 13:2, (211-224), Online publication date: 1-Mar-1977. Greenberg J and Reivich M (1977) Response time of cerebral arterioles to alterations in extravascular fluid pH, Microvascular Research, 10.1016/0026-2862(77)90032-2, 14:3, (383-393), Online publication date: 1-Nov-1977. Bates D and Sundt T (1976) The relevance of peripheral baroreceptors and chemoreceptors to regulation of cerebral blood flow in the cat., Circulation Research, 38:6, (488-493), Online publication date: 1-Jun-1976.WEI E, RAPER A, KONTOS H and PATTERSON J (1975) Determinants of Response of Pial Arteries to Norepinephrine and Sympathetic Nerve Stimulation, Stroke, 6:6, (654-658), Online publication date: 1-Nov-1975.HERZ D, BAEZ S and SHULMAN K (1975) Pial Microcirculation in Subarachnoid Hemorrhage, Stroke, 6:4, (417-424), Online publication date: 1-Jul-1975.LEVASSEUR J, WEI E, RAPER A, KONTOS H and PATTERSON J (1975) Detailed Description of a Cranial Window Technique for Acute and Chronic Experiments, Stroke, 6:3, (308-317), Online publication date: 1-May-1975.ROSENBLUM W and KONTOS H (1974) Editorial , Stroke, 5:4, (425-428), Online publication date: 1-Jul-1974. Ma Y, Koo A, Kwan H and Cheng K (1974) On-line measurement of the dynamic velocity of erythrocytes in the cerebral microvessels in the rat, Microvascular Research, 10.1016/0026-2862(74)90059-4, 8:1, (1-13), Online publication date: 1-Jul-1974. DULING B (1973) Changes in Microvascular Diameter and Oxygen Tension Induced by Carbon Dioxide, Circulation Research, 32:3, (370-376), Online publication date: 1-Mar-1973.MEYER J, SHIMAZU K, OKAMOTO S, KOTO A, OHUCHI T, SARI A and ERICSSON A (1973) Effects of Alpha Adrenergic Blockade on Autoregulation and Chemical Vasomotor Control of CBF in Stroke, Stroke, 4:2, (187-200), Online publication date: 1-Mar-1973.Raper A, Kontos H, Wei E and Patterson J (1972) Unresponsiveness of Pial Precapillary Vessels to Catecholamines and Sympathetic Nerve Stimulation, Circulation Research, 31:2, (257-266), Online publication date: 1-Aug-1972.Stromberg D and Fox J (1972) Pressures in the Pial Arterial Microcirculation of the Cat during Changes in Systemic Arterial Blood Pressure, Circulation Research, 31:2, (229-239), Online publication date: 1-Aug-1972. Yeo L, Arnberg F, Chireh A, Sharma V, Tan B, Gontu V, Little P and Holmin S (2022) The Role of Carbon Dioxide in the Rat Acute Stroke Penumbra, Frontiers in Digital Health, 10.3389/fdgth.2021.824334, 3 May 1, 1971Vol 28, Issue 5 Advertisement Article InformationMetrics Copyright copyright 1971 by the American Heart Association, Inc.https://doi.org/10.1161/01.RES.28.5.518 Manuscript receivedOctober 27, 1970Manuscript acceptedFebruary 23, 1971Originally publishedMay 1, 1971 Keywordshypercapniahypocapniaarterioles catcerebral blood vesselsPDF download Advertisement" @default.
• W2620239524 created "2017-06-05" @default.
• W2620239524 creator A5025621134 @default.
• W2620239524 creator A5072370459 @default.
• W2620239524 creator A5089358233 @default.
• W2620239524 date "1971-05-01" @default.
• W2620239524 modified "2023-10-18" @default.
• W2620239524 title "Response of Pial Precapillary Vessels to Changes in Arterial Carbon Dioxide Tension" @default.
• W2620239524 doi "https://doi.org/10.1161/01.res.28.5.518" @default.
• W2620239524 hasPublicationYear "1971" @default.
• W2620239524 type Work @default.
• W2620239524 sameAs 2620239524 @default.
• W2620239524 citedByCount "74" @default.
• W2620239524 countsByYear W26202395242012 @default.
• W2620239524 countsByYear W26202395242013 @default.
• W2620239524 countsByYear W26202395242021 @default.
• W2620239524 countsByYear W26202395242022 @default.
• W2620239524 countsByYear W26202395242023 @default.
• W2620239524 crossrefType "journal-article" @default.
• W2620239524 hasAuthorship W2620239524A5025621134 @default.
• W2620239524 hasAuthorship W2620239524A5072370459 @default.
• W2620239524 hasAuthorship W2620239524A5089358233 @default.
• W2620239524 hasBestOaLocation W26202395241 @default.
• W2620239524 hasConcept C126322002 @default.
• W2620239524 hasConcept C164705383 @default.
• W2620239524 hasConcept C178790620 @default.
• W2620239524 hasConcept C185592680 @default.
• W2620239524 hasConcept C530467964 @default.
• W2620239524 hasConcept C71924100 @default.
• W2620239524 hasConceptScore W2620239524C126322002 @default.
• W2620239524 hasConceptScore W2620239524C164705383 @default.
• W2620239524 hasConceptScore W2620239524C178790620 @default.
• W2620239524 hasConceptScore W2620239524C185592680 @default.
• W2620239524 hasConceptScore W2620239524C530467964 @default.
• W2620239524 hasConceptScore W2620239524C71924100 @default.
• W2620239524 hasIssue "5" @default.
• W2620239524 hasLocation W26202395241 @default.
• W2620239524 hasOpenAccess W2620239524 @default.
• W2620239524 hasPrimaryLocation W26202395241 @default.
• W2620239524 hasRelatedWork W1531601525 @default.
• W2620239524 hasRelatedWork W2748952813 @default.
• W2620239524 hasRelatedWork W2758277628 @default.
• W2620239524 hasRelatedWork W2899084033 @default.
• W2620239524 hasRelatedWork W2935909890 @default.
• W2620239524 hasRelatedWork W2948807893 @default.
• W2620239524 hasRelatedWork W3173606202 @default.
• W2620239524 hasRelatedWork W3183948672 @default.
• W2620239524 hasRelatedWork W2778153218 @default.
• W2620239524 hasRelatedWork W3110381201 @default.
• W2620239524 hasVolume "28" @default.
• W2620239524 isParatext "false" @default.
• W2620239524 isRetracted "false" @default.
• W2620239524 magId "2620239524" @default.
• W2620239524 workType "article" @default.