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- W2620296884 abstract "Heteromer star-shaped nanoparticles have the potential to carry out therapeutic agents, improve intracellular uptake, and safely release drugs after prolonged periods of residence at the diseased site. A one-step seed mediation process was employed using polylactide-co-glycolic acid (PLGA), polyvinyl alcohol (PVA), silver nitrate, and tetrakis(hydroxymethyl)phosphonium chloride (THPC). Mixing these reagents followed by UV irradiation successfully produced heteromer nanostars containing a number of arm chains attached to a single core with a high yield. The release of THPC from heteromer nanostars was tested for its potential use for breast cancer treatment. The nanostars present a unique geometrical design exhibiting a significant intracellular uptake by breast cancer cells but low cytotoxicity that potentiates its efficacy as drug carriers." @default.
- W2620296884 created "2017-06-05" @default.
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- W2620296884 date "2017-05-31" @default.
- W2620296884 modified "2023-09-26" @default.
- W2620296884 title "Heteromer Nanostars by Spontaneous Self-Assembly" @default.
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- W2620296884 doi "https://doi.org/10.3390/nano7060127" @default.
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