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• W2620310967 abstract "Understanding the mechanisms driving tissue and organ formation requires knowledge across scales. How do signaling pathways specify distinct tissue types? How does the patterning system control morphogenesis? How do these processes evolve? The Drosophila egg chamber, where EGF and BMP signaling intersect to specify unique cell types that construct epithelial tubes for specialized eggshell structures, has provided a tractable system to ask these questions. Work there has elucidated connections between scales of development, including across evolutionary scales, and fostered the development of quantitative modeling tools. These tools and general principles can be applied to the understanding of other developmental processes across organisms. Understanding the mechanisms driving tissue and organ formation requires knowledge across scales. How do signaling pathways specify distinct tissue types? How does the patterning system control morphogenesis? How do these processes evolve? The Drosophila egg chamber, where EGF and BMP signaling intersect to specify unique cell types that construct epithelial tubes for specialized eggshell structures, has provided a tractable system to ask these questions. Work there has elucidated connections between scales of development, including across evolutionary scales, and fostered the development of quantitative modeling tools. These tools and general principles can be applied to the understanding of other developmental processes across organisms." @default.
• W2620310967 created "2017-06-05" @default.
• W2620310967 creator A5012005058 @default.
• W2620310967 creator A5023817694 @default.
• W2620310967 creator A5067588572 @default.
• W2620310967 date "2017-05-01" @default.
• W2620310967 modified "2023-09-26" @default.
• W2620310967 title "Epithelial Patterning, Morphogenesis, and Evolution: Drosophila Eggshell as a Model" @default.
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