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- W2620486585 abstract "Germ cell tumors arise from errors occurring during the migration of embryonic stem cells to the gonads. They constitute 10-15% of malignant mediastinal tumors. Thirty-nine years old male patient was admitted with shortness of breath and gynecomastia. Positron emission tomography / Computed tomography (PET/CT) showed hypermetabolic mediastinal mass in the anterior mediastinum. Serum tumor markers were elevated. Mixed germ cell tumor was diagnosed via transthoracic tru-cut biopsy. After three cycles of systemic cisplatin, etoposide and bleomycin treatment, PET/CT showed a decreased metabolic activity but an increase in the size of mass. Growing teratoma syndrome was diagnosed. The excision of the mass was performed via a median sternotomy. Then autologous stem cell transplantation was performed. Patients was presented as a successful example of a multimodality treatment of a primary mediastinal germ cell tumor with GTS." @default.
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- W2620486585 date "2016-01-01" @default.
- W2620486585 modified "2023-10-17" @default.
- W2620486585 title "Multimodality treatment of primary mediastinal germ cell tumor with growing teratoma syndrome: a case report" @default.
- W2620486585 doi "https://doi.org/10.26663/cts.2016.0006" @default.
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