FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2621132009> ?p ?o ?g. }

• W2621132009 endingPage "721" @default.
• W2621132009 startingPage "718" @default.
• W2621132009 abstract "Maternal autoantibodies to neuronal proteins may be one cause of neurodevelopmental disorders. This exploratory study used the Danish archived midgestational sera and their nationwide registers to search for antibodies to the N-methyl-D-aspartate receptor (NMDAR) and contactin-associated protein-like 2 (CASPR2) in maternal sera, and to relate them to subsequent psychiatric diagnoses in the woman or her child.In a sample of 192 women, there was no association between antibody status and subsequent psychosis in the mothers. However, NMDAR antibodies (n=4) or CASPR2 antibodies (n=1) were identified in 5/11 (45.5%) women whose children were given a diagnosis of mild or unspecified mental retardation or disorders of psychological and motor development (collectively abbreviated as mental retardation and/or disorders of psychological development (MR/DPD)) compared with 9/176 (5.1%) of the remaining mother (p<0.001). These findings were followed up in a specifically selected cohort, in which CASPR2 antibodies were detected in 7/171 (4.1%) mothers of MR/DPD progeny, compared with only 1/171 (0.6%) control mother (p=0.067). The combined sample showed a significantly higher frequency of CASPR2 antibodies in mothers of MD/DPD children (p=0.01). These autoantibodies were not increased in mothers of children with autistic spectrum disorder.These findings complement the known roles of CASPR2 in brain development, and warrant further epidemiological and experimental studies to clarify the role of CASPR2 and possibly other antibodies in neurodevelopmental disorders." @default.
• W2621132009 created "2017-06-09" @default.
• W2621132009 creator A5000002927 @default.
• W2621132009 creator A5022635248 @default.
• W2621132009 creator A5034065168 @default.
• W2621132009 creator A5036690443 @default.
• W2621132009 creator A5038243561 @default.
• W2621132009 creator A5050681797 @default.
• W2621132009 creator A5061525861 @default.
• W2621132009 creator A5062939642 @default.
• W2621132009 date "2017-06-01" @default.
• W2621132009 modified "2023-10-16" @default.
• W2621132009 title "CASPR2 autoantibodies are raised during pregnancy in mothers of children with mental retardation and disorders of psychological development but not autism" @default.
• W2621132009 cites W1885358257 @default.
• W2621132009 cites W1944285573 @default.
• W2621132009 cites W2037433854 @default.
• W2621132009 cites W2076805831 @default.
• W2621132009 cites W2097401631 @default.
• W2621132009 cites W2100252544 @default.
• W2621132009 cites W2102420102 @default.
• W2621132009 cites W2105371617 @default.
• W2621132009 cites W2113126716 @default.
• W2621132009 cites W2118067546 @default.
• W2621132009 cites W2118922889 @default.
• W2621132009 cites W2150720513 @default.
• W2621132009 cites W2164091580 @default.
• W2621132009 cites W2319347158 @default.
• W2621132009 cites W2344412319 @default.
• W2621132009 cites W2529422719 @default.
• W2621132009 cites W4240153611 @default.
• W2621132009 doi "https://doi.org/10.1136/jnnp-2016-315251" @default.
• W2621132009 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5561372" @default.
• W2621132009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28572274" @default.
• W2621132009 hasPublicationYear "2017" @default.
• W2621132009 type Work @default.
• W2621132009 sameAs 2621132009 @default.
• W2621132009 citedByCount "39" @default.
• W2621132009 countsByYear W26211320092017 @default.
• W2621132009 countsByYear W26211320092018 @default.
• W2621132009 countsByYear W26211320092019 @default.
• W2621132009 countsByYear W26211320092020 @default.
• W2621132009 countsByYear W26211320092021 @default.
• W2621132009 countsByYear W26211320092022 @default.
• W2621132009 countsByYear W26211320092023 @default.
• W2621132009 crossrefType "journal-article" @default.
• W2621132009 hasAuthorship W2621132009A5000002927 @default.
• W2621132009 hasAuthorship W2621132009A5022635248 @default.
• W2621132009 hasAuthorship W2621132009A5034065168 @default.
• W2621132009 hasAuthorship W2621132009A5036690443 @default.
• W2621132009 hasAuthorship W2621132009A5038243561 @default.
• W2621132009 hasAuthorship W2621132009A5050681797 @default.
• W2621132009 hasAuthorship W2621132009A5061525861 @default.
• W2621132009 hasAuthorship W2621132009A5062939642 @default.
• W2621132009 hasBestOaLocation W26211320091 @default.
• W2621132009 hasConcept C107130276 @default.
• W2621132009 hasConcept C118552586 @default.
• W2621132009 hasConcept C126322002 @default.
• W2621132009 hasConcept C159654299 @default.
• W2621132009 hasConcept C163764329 @default.
• W2621132009 hasConcept C203014093 @default.
• W2621132009 hasConcept C205778803 @default.
• W2621132009 hasConcept C2776412080 @default.
• W2621132009 hasConcept C2779234561 @default.
• W2621132009 hasConcept C2779727114 @default.
• W2621132009 hasConcept C54355233 @default.
• W2621132009 hasConcept C71924100 @default.
• W2621132009 hasConcept C72563966 @default.
• W2621132009 hasConcept C86803240 @default.
• W2621132009 hasConceptScore W2621132009C107130276 @default.
• W2621132009 hasConceptScore W2621132009C118552586 @default.
• W2621132009 hasConceptScore W2621132009C126322002 @default.
• W2621132009 hasConceptScore W2621132009C159654299 @default.
• W2621132009 hasConceptScore W2621132009C163764329 @default.
• W2621132009 hasConceptScore W2621132009C203014093 @default.
• W2621132009 hasConceptScore W2621132009C205778803 @default.
• W2621132009 hasConceptScore W2621132009C2776412080 @default.
• W2621132009 hasConceptScore W2621132009C2779234561 @default.
• W2621132009 hasConceptScore W2621132009C2779727114 @default.
• W2621132009 hasConceptScore W2621132009C54355233 @default.
• W2621132009 hasConceptScore W2621132009C71924100 @default.
• W2621132009 hasConceptScore W2621132009C72563966 @default.
• W2621132009 hasConceptScore W2621132009C86803240 @default.
• W2621132009 hasFunder F4320309530 @default.
• W2621132009 hasIssue "9" @default.
• W2621132009 hasLocation W26211320091 @default.
• W2621132009 hasLocation W26211320092 @default.
• W2621132009 hasLocation W26211320093 @default.
• W2621132009 hasLocation W26211320094 @default.
• W2621132009 hasLocation W26211320095 @default.
• W2621132009 hasLocation W26211320096 @default.
• W2621132009 hasOpenAccess W2621132009 @default.
• W2621132009 hasPrimaryLocation W26211320091 @default.
• W2621132009 hasRelatedWork W1995350144 @default.
• W2621132009 hasRelatedWork W2227393071 @default.
• W2621132009 hasRelatedWork W2601691194 @default.
• W2621132009 hasRelatedWork W2604923520 @default.
• W2621132009 hasRelatedWork W2784784403 @default.
• W2621132009 hasRelatedWork W3133980636 @default.

• next