Matches in SemOpenAlex for { <https://semopenalex.org/work/W2621175283> ?p ?o ?g. }
- W2621175283 endingPage "450" @default.
- W2621175283 startingPage "441" @default.
- W2621175283 abstract "In this work chitosan-hyaluronic acid composite sponge scaffold enriched with Andrographolide (AND) lipid nanocarriers was developed. Nanocarriers were prepared using solvent diffusion method by applying 23 factorial design. NLC4 had the highest desirability value (0.882) and therefore, it was chosen as an optimal nanocarrier. Itexhibited spherical shape with 253nm, 83.04% entrapment efficiency and a prolonged release of AND up to 48-h. Consecutively, NLC4 was incorporated in a chitosan-hyaluronic acid gel and lyophilized for 24h to obtain chitosan-hyaluronic acid/NLC4 nanocomposite sponge to enhance AND delivery to wound sites. The morphology of sponge was characterized by scanning electron microscopy. Nanocomposites showed a porosity of 56.22% with enhanced swelling. The in vivo evaluation in rats reveals that the chitosan-hyaluronic acid/NLC4 sponge enhances the wound healing with no scar and improved tissue quality. These results strongly support the possibility of using this novel chitosan-hyaluronic acid/NLC4 sponge for wound care application." @default.
- W2621175283 created "2017-06-09" @default.
- W2621175283 creator A5052108962 @default.
- W2621175283 creator A5052251727 @default.
- W2621175283 date "2017-10-01" @default.
- W2621175283 modified "2023-10-16" @default.
- W2621175283 title "Chitosan–hyaluronic acid composite sponge scaffold enriched with Andrographolide-loaded lipid nanoparticles for enhanced wound healing" @default.
- W2621175283 cites W1504238689 @default.
- W2621175283 cites W1764330003 @default.
- W2621175283 cites W1828270512 @default.
- W2621175283 cites W1967354534 @default.
- W2621175283 cites W1968651552 @default.
- W2621175283 cites W1972516841 @default.
- W2621175283 cites W1978477577 @default.
- W2621175283 cites W1983489155 @default.
- W2621175283 cites W1984685797 @default.
- W2621175283 cites W1992714402 @default.
- W2621175283 cites W1993788795 @default.
- W2621175283 cites W2003169609 @default.
- W2621175283 cites W2012707522 @default.
- W2621175283 cites W2013484723 @default.
- W2621175283 cites W2025967915 @default.
- W2621175283 cites W2031095463 @default.
- W2621175283 cites W2037946525 @default.
- W2621175283 cites W2051499572 @default.
- W2621175283 cites W2054103003 @default.
- W2621175283 cites W2058837930 @default.
- W2621175283 cites W2061385800 @default.
- W2621175283 cites W2063674178 @default.
- W2621175283 cites W2064783636 @default.
- W2621175283 cites W2068983836 @default.
- W2621175283 cites W2073983855 @default.
- W2621175283 cites W2079770446 @default.
- W2621175283 cites W2082516633 @default.
- W2621175283 cites W2092421291 @default.
- W2621175283 cites W2097730243 @default.
- W2621175283 cites W2114239060 @default.
- W2621175283 cites W2114697324 @default.
- W2621175283 cites W2117104281 @default.
- W2621175283 cites W2160190446 @default.
- W2621175283 cites W2161104679 @default.
- W2621175283 cites W2161713866 @default.
- W2621175283 cites W2229086138 @default.
- W2621175283 cites W2288456615 @default.
- W2621175283 cites W2301946603 @default.
- W2621175283 cites W2346149706 @default.
- W2621175283 cites W2517304913 @default.
- W2621175283 cites W2521041133 @default.
- W2621175283 cites W2548838368 @default.
- W2621175283 cites W368189948 @default.
- W2621175283 cites W868859376 @default.
- W2621175283 doi "https://doi.org/10.1016/j.carbpol.2017.05.098" @default.
- W2621175283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28732886" @default.
- W2621175283 hasPublicationYear "2017" @default.
- W2621175283 type Work @default.
- W2621175283 sameAs 2621175283 @default.
- W2621175283 citedByCount "92" @default.
- W2621175283 countsByYear W26211752832018 @default.
- W2621175283 countsByYear W26211752832019 @default.
- W2621175283 countsByYear W26211752832020 @default.
- W2621175283 countsByYear W26211752832021 @default.
- W2621175283 countsByYear W26211752832022 @default.
- W2621175283 countsByYear W26211752832023 @default.
- W2621175283 crossrefType "journal-article" @default.
- W2621175283 hasAuthorship W2621175283A5052108962 @default.
- W2621175283 hasAuthorship W2621175283A5052251727 @default.
- W2621175283 hasConcept C104779481 @default.
- W2621175283 hasConcept C105702510 @default.
- W2621175283 hasConcept C141071460 @default.
- W2621175283 hasConcept C155672457 @default.
- W2621175283 hasConcept C159985019 @default.
- W2621175283 hasConcept C171250308 @default.
- W2621175283 hasConcept C18150654 @default.
- W2621175283 hasConcept C185592680 @default.
- W2621175283 hasConcept C192562407 @default.
- W2621175283 hasConcept C2777529286 @default.
- W2621175283 hasConcept C2778540859 @default.
- W2621175283 hasConcept C2778849931 @default.
- W2621175283 hasConcept C2779732960 @default.
- W2621175283 hasConcept C2780269544 @default.
- W2621175283 hasConcept C2781357234 @default.
- W2621175283 hasConcept C55493867 @default.
- W2621175283 hasConcept C59822182 @default.
- W2621175283 hasConcept C71924100 @default.
- W2621175283 hasConcept C86803240 @default.
- W2621175283 hasConceptScore W2621175283C104779481 @default.
- W2621175283 hasConceptScore W2621175283C105702510 @default.
- W2621175283 hasConceptScore W2621175283C141071460 @default.
- W2621175283 hasConceptScore W2621175283C155672457 @default.
- W2621175283 hasConceptScore W2621175283C159985019 @default.
- W2621175283 hasConceptScore W2621175283C171250308 @default.
- W2621175283 hasConceptScore W2621175283C18150654 @default.
- W2621175283 hasConceptScore W2621175283C185592680 @default.
- W2621175283 hasConceptScore W2621175283C192562407 @default.
- W2621175283 hasConceptScore W2621175283C2777529286 @default.
- W2621175283 hasConceptScore W2621175283C2778540859 @default.
- W2621175283 hasConceptScore W2621175283C2778849931 @default.
- W2621175283 hasConceptScore W2621175283C2779732960 @default.