FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2622021625> ?p ?o ?g. }

• W2622021625 endingPage "141" @default.
• W2622021625 startingPage "135" @default.
• W2622021625 abstract "Depleted uranium (DU) is a radioactive heavy metal used primarily in military applications. Published data from our laboratory have demonstrated that DU exposure in vitro to immortalized human osteoblast cells (HOS) is both neoplastically transforming and genotoxic. In vivo studies have also demonstrated that DU is leukemogenic and genotoxic. DU possesses both a radiological (alpha particle) and chemical (metal) component but is generally considered a chemical biohazard. Studies have shown that alpha particle radiation does play a role in DU's toxic effects. Evidence has accumulated that non-irradiated cells in the vicinity of irradiated cells can have a response to ionization events. The purpose of this study was to determine if these “bystander effects” play a role in DU's toxic and neoplastic effects using HOS cells. We investigated the bystander responses between DU-exposed cells and non-exposed cells by co-culturing the two equal populations. Decreased cell survival and increased neoplastic transformation were observed in the non-DU exposed cells following 4 or 24 h co-culture. In contrast Ni (II)- or Cr(VI)- exposed cells were unable to alter those biological effects in non-Ni(II) or non-Cr(VI) exposed co-cultured cells. Transfer experiments using medium from the DU-exposed and non-exposed co-cultured cells was able to cause adverse biological responses in cells; these results demonstrated that a factor (s) is secreted into the co-culture medium which is involved in this DU-associated bystander effect. This novel effect of DU exposure could have implications for radiation risk and for health risk assessment associated with DU exposure." @default.
• W2622021625 created "2017-06-15" @default.
• W2622021625 creator A5007186400 @default.
• W2622021625 creator A5016262021 @default.
• W2622021625 creator A5048201953 @default.
• W2622021625 creator A5057087348 @default.
• W2622021625 creator A5057287196 @default.
• W2622021625 creator A5058827866 @default.
• W2622021625 creator A5067377055 @default.
• W2622021625 date "2017-09-01" @default.
• W2622021625 modified "2023-10-09" @default.
• W2622021625 title "Radiation exposure from depleted uranium: The radiation bystander effect" @default.
• W2622021625 cites W183996239 @default.
• W2622021625 cites W1975996585 @default.
• W2622021625 cites W1981797176 @default.
• W2622021625 cites W1985652307 @default.
• W2622021625 cites W1986087075 @default.
• W2622021625 cites W1991134224 @default.
• W2622021625 cites W1992845765 @default.
• W2622021625 cites W2001740472 @default.
• W2622021625 cites W2005341703 @default.
• W2622021625 cites W2007381631 @default.
• W2622021625 cites W2008049232 @default.
• W2622021625 cites W2021297107 @default.
• W2622021625 cites W2036052797 @default.
• W2622021625 cites W2047370460 @default.
• W2622021625 cites W2066537849 @default.
• W2622021625 cites W2067327293 @default.
• W2622021625 cites W2081026740 @default.
• W2622021625 cites W2109637975 @default.
• W2622021625 cites W2114023129 @default.
• W2622021625 cites W2116641236 @default.
• W2622021625 cites W2120389087 @default.
• W2622021625 cites W2120936400 @default.
• W2622021625 cites W2124803506 @default.
• W2622021625 cites W2132305988 @default.
• W2622021625 cites W2134597005 @default.
• W2622021625 cites W2155308670 @default.
• W2622021625 cites W2162749839 @default.
• W2622021625 cites W2164856505 @default.
• W2622021625 cites W2167894711 @default.
• W2622021625 cites W2173782486 @default.
• W2622021625 cites W2195490444 @default.
• W2622021625 cites W3021506225 @default.
• W2622021625 doi "https://doi.org/10.1016/j.taap.2017.06.004" @default.
• W2622021625 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28602947" @default.
• W2622021625 hasPublicationYear "2017" @default.
• W2622021625 type Work @default.
• W2622021625 sameAs 2622021625 @default.
• W2622021625 citedByCount "13" @default.
• W2622021625 countsByYear W26220216252018 @default.
• W2622021625 countsByYear W26220216252019 @default.
• W2622021625 countsByYear W26220216252020 @default.
• W2622021625 countsByYear W26220216252021 @default.
• W2622021625 countsByYear W26220216252022 @default.
• W2622021625 countsByYear W26220216252023 @default.
• W2622021625 crossrefType "journal-article" @default.
• W2622021625 hasAuthorship W2622021625A5007186400 @default.
• W2622021625 hasAuthorship W2622021625A5016262021 @default.
• W2622021625 hasAuthorship W2622021625A5048201953 @default.
• W2622021625 hasAuthorship W2622021625A5057087348 @default.
• W2622021625 hasAuthorship W2622021625A5057287196 @default.
• W2622021625 hasAuthorship W2622021625A5058827866 @default.
• W2622021625 hasAuthorship W2622021625A5067377055 @default.
• W2622021625 hasBestOaLocation W26220216251 @default.
• W2622021625 hasConcept C104317684 @default.
• W2622021625 hasConcept C111337013 @default.
• W2622021625 hasConcept C121332964 @default.
• W2622021625 hasConcept C153911025 @default.
• W2622021625 hasConcept C178790620 @default.
• W2622021625 hasConcept C18231593 @default.
• W2622021625 hasConcept C185544564 @default.
• W2622021625 hasConcept C185592680 @default.
• W2622021625 hasConcept C19106626 @default.
• W2622021625 hasConcept C202751555 @default.
• W2622021625 hasConcept C203014093 @default.
• W2622021625 hasConcept C207001950 @default.
• W2622021625 hasConcept C2778959862 @default.
• W2622021625 hasConcept C29730261 @default.
• W2622021625 hasConcept C2993273003 @default.
• W2622021625 hasConcept C33070731 @default.
• W2622021625 hasConcept C502942594 @default.
• W2622021625 hasConcept C54355233 @default.
• W2622021625 hasConcept C55493867 @default.
• W2622021625 hasConcept C555283112 @default.
• W2622021625 hasConcept C81885089 @default.
• W2622021625 hasConcept C86803240 @default.
• W2622021625 hasConcept C95444343 @default.
• W2622021625 hasConceptScore W2622021625C104317684 @default.
• W2622021625 hasConceptScore W2622021625C111337013 @default.
• W2622021625 hasConceptScore W2622021625C121332964 @default.
• W2622021625 hasConceptScore W2622021625C153911025 @default.
• W2622021625 hasConceptScore W2622021625C178790620 @default.
• W2622021625 hasConceptScore W2622021625C18231593 @default.
• W2622021625 hasConceptScore W2622021625C185544564 @default.
• W2622021625 hasConceptScore W2622021625C185592680 @default.
• W2622021625 hasConceptScore W2622021625C19106626 @default.
• W2622021625 hasConceptScore W2622021625C202751555 @default.

• next