FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2622160775> ?p ?o ?g. }

• W2622160775 abstract "The macroscopic growth of brain tumors has been studied by means of different computational modeling approaches. Glioblastoma multiforme (GBM) is the most common malignant type and is commonly modeled as a reaction–diffusion type system, accounting for its invasive growth pattern. Purely biomechanical models have been proposed to represent the mass effect caused by the growing tumor, but only a few models consider mass effect and tissue invasion effects in a single 3D model. We report first results of a comparative study that evaluates the ability of a simple computational model to reproduce the shape of pathologies found in patients. GBM invasion into brain tissue and the mechanical interaction between tumor and healthy tissue components are simulated using the finite element method (FEM). Cell proliferation and invasion are modeled as a reaction–diffusion process; simulation of the mechanic interaction relies on a linear elastic material model. Both are coupled by relating the local increase in tumor cell concentration to the generation of isotropic strain in the corresponding tissue element. The model accounts for multiple brain regions with values for proliferation, isotropic diffusion, and mechanical properties derived from literature. Tumors were seeded at multiple locations in FEM models derived from publicly available human brain atlases. Simulation results for a given tumor volume were compared to patient images. Simulated tumors showed a more symmetric growth pattern compared to their real counterparts. Resulting levels of tumor invasiveness were in agreement with simulation parameters and tumor-induced pressures of realistic magnitude were found." @default.
• W2622160775 created "2017-06-15" @default.
• W2622160775 creator A5042052436 @default.
• W2622160775 creator A5055346737 @default.
• W2622160775 date "2017-08-31" @default.
• W2622160775 modified "2023-09-27" @default.
• W2622160775 title "Evaluation of a Mechanically Coupled Reaction–Diffusion Model for Macroscopic Brain Tumor Growth" @default.
• W2622160775 cites W1520028666 @default.
• W2622160775 cites W1606346782 @default.
• W2622160775 cites W1969684282 @default.
• W2622160775 cites W1976110908 @default.
• W2622160775 cites W1984580487 @default.
• W2622160775 cites W1990245134 @default.
• W2622160775 cites W1997542574 @default.
• W2622160775 cites W2022101728 @default.
• W2622160775 cites W2024080420 @default.
• W2622160775 cites W2025104440 @default.
• W2622160775 cites W2028569674 @default.
• W2622160775 cites W2037316890 @default.
• W2622160775 cites W2042115479 @default.
• W2622160775 cites W2055272161 @default.
• W2622160775 cites W2061575214 @default.
• W2622160775 cites W2071948601 @default.
• W2622160775 cites W2079949023 @default.
• W2622160775 cites W2088292624 @default.
• W2622160775 cites W2098341282 @default.
• W2622160775 cites W2106235379 @default.
• W2622160775 cites W2112130807 @default.
• W2622160775 cites W2130257210 @default.
• W2622160775 cites W2135558784 @default.
• W2622160775 cites W2139899744 @default.
• W2622160775 cites W2140157574 @default.
• W2622160775 cites W2157358125 @default.
• W2622160775 cites W2160645528 @default.
• W2622160775 cites W2171157655 @default.
• W2622160775 cites W4242568052 @default.
• W2622160775 doi "https://doi.org/10.1007/978-3-319-59764-5_7" @default.
• W2622160775 hasPublicationYear "2017" @default.
• W2622160775 type Work @default.
• W2622160775 sameAs 2622160775 @default.
• W2622160775 citedByCount "1" @default.
• W2622160775 countsByYear W26221607752019 @default.
• W2622160775 crossrefType "book-chapter" @default.
• W2622160775 hasAuthorship W2622160775A5042052436 @default.
• W2622160775 hasAuthorship W2622160775A5055346737 @default.
• W2622160775 hasConcept C121332964 @default.
• W2622160775 hasConcept C126838900 @default.
• W2622160775 hasConcept C135628077 @default.
• W2622160775 hasConcept C136229726 @default.
• W2622160775 hasConcept C141071460 @default.
• W2622160775 hasConcept C142724271 @default.
• W2622160775 hasConcept C143409427 @default.
• W2622160775 hasConcept C149550507 @default.
• W2622160775 hasConcept C169760540 @default.
• W2622160775 hasConcept C184050105 @default.
• W2622160775 hasConcept C186060115 @default.
• W2622160775 hasConcept C2775941986 @default.
• W2622160775 hasConcept C2776194525 @default.
• W2622160775 hasConcept C2779130545 @default.
• W2622160775 hasConcept C2779662492 @default.
• W2622160775 hasConcept C2986936838 @default.
• W2622160775 hasConcept C502942594 @default.
• W2622160775 hasConcept C62520636 @default.
• W2622160775 hasConcept C69357855 @default.
• W2622160775 hasConcept C71924100 @default.
• W2622160775 hasConcept C86803240 @default.
• W2622160775 hasConcept C97355855 @default.
• W2622160775 hasConceptScore W2622160775C121332964 @default.
• W2622160775 hasConceptScore W2622160775C126838900 @default.
• W2622160775 hasConceptScore W2622160775C135628077 @default.
• W2622160775 hasConceptScore W2622160775C136229726 @default.
• W2622160775 hasConceptScore W2622160775C141071460 @default.
• W2622160775 hasConceptScore W2622160775C142724271 @default.
• W2622160775 hasConceptScore W2622160775C143409427 @default.
• W2622160775 hasConceptScore W2622160775C149550507 @default.
• W2622160775 hasConceptScore W2622160775C169760540 @default.
• W2622160775 hasConceptScore W2622160775C184050105 @default.
• W2622160775 hasConceptScore W2622160775C186060115 @default.
• W2622160775 hasConceptScore W2622160775C2775941986 @default.
• W2622160775 hasConceptScore W2622160775C2776194525 @default.
• W2622160775 hasConceptScore W2622160775C2779130545 @default.
• W2622160775 hasConceptScore W2622160775C2779662492 @default.
• W2622160775 hasConceptScore W2622160775C2986936838 @default.
• W2622160775 hasConceptScore W2622160775C502942594 @default.
• W2622160775 hasConceptScore W2622160775C62520636 @default.
• W2622160775 hasConceptScore W2622160775C69357855 @default.
• W2622160775 hasConceptScore W2622160775C71924100 @default.
• W2622160775 hasConceptScore W2622160775C86803240 @default.
• W2622160775 hasConceptScore W2622160775C97355855 @default.
• W2622160775 hasLocation W26221607751 @default.
• W2622160775 hasOpenAccess W2622160775 @default.
• W2622160775 hasPrimaryLocation W26221607751 @default.
• W2622160775 hasRelatedWork W1977834903 @default.
• W2622160775 hasRelatedWork W1994745899 @default.
• W2622160775 hasRelatedWork W2001739816 @default.
• W2622160775 hasRelatedWork W2038607477 @default.
• W2622160775 hasRelatedWork W2088675153 @default.
• W2622160775 hasRelatedWork W2121247990 @default.
• W2622160775 hasRelatedWork W2141045864 @default.
• W2622160775 hasRelatedWork W2211977022 @default.

• next