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• W2622428073 abstract "Until recently, Denmark was considered free of iodine deficiency disorders. It had been demonstrated that urinary iodine excretion was low, with geographical variation now caused by differences in groundwater iodine content. However, goiter was not a clinical problem in children, and a national survey of more than 350000 schoolchildren did not support the necessity of an iodine fortification program. When focus turned to other parts of the population, the consequences of iodine deficiency was clear: multinodular goiter with a high occurrence of clinical and subclinical hyperthyroidism was extraordinarily common in the elderly, and pregnant women showed signs of insufficient thyroid hormone production in late pregnancy. Mild-to-moderate ID in a well-nourished population leads to a frequent occurrence of goiter and hyperthyroidism in the elderly. There may be impairment of thyroid function in pregnant women. A mandatory iodization of household salt and bread salt has led to a well-distributed increase in iodine intake in the Danish population. The Danish iodization program has led to a decrease in thyroid size and frequency of thyroid enlargement in practically all groups investigated. Iodine intake of a population should be monitored and the use of iodine-containing substances in farming and the food industry should be regulated. A program targeted to increase daily iodine intake by around 50 μg was started by the National Food Agency. The DanThyr monitoring program has shown that the populations iodine intake has increased much as planned by adding iodine (13 ppm) to table salt and bread salt. Thyroid size and the occurrence of thyroid enlargement have diminished in all age groups. There has been a small increase in the incidence of overt hyperthyroidism, which is expected to be transient." @default.
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• W2622428073 date "2009-01-01" @default.
• W2622428073 modified "2023-09-27" @default.
• W2622428073 title "Surveillance of Thyroid Disorders and Iodine Intake in the Danish Population before and after Mandatory Iodide Fortification of Salt" @default.
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• W2622428073 doi "https://doi.org/10.1016/b978-0-12-374135-6.00119-9" @default.
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