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• W2622813183 endingPage "11720" @default.
• W2622813183 startingPage "11715" @default.
• W2622813183 abstract "Significance We generated genomic data to estimate the population history of grapes, the most economically important horticultural crop in the world. Domesticated grapes experienced a protracted, 22,000-y population decline prior to domestication; we hypothesize that this decline reflects low-intensity cultivation by humans prior to domestication. Domestication altered the mating system of grapes. The sex determination region is detectable as a region of heightened genetic divergence between wild and cultivated accessions. Based on gene expression analyses, we propose candidate genes that alter sex determination. Finally, grapes contain more deleterious mutations in heterozygous states than do their wild ancestors. The accumulation of deleterious mutations is due in part to clonal propagation, which shelters deleterious recessive mutations." @default.
• W2622813183 created "2017-06-15" @default.
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• W2622813183 creator A5069257993 @default.
• W2622813183 creator A5073014049 @default.
• W2622813183 date "2017-10-17" @default.
• W2622813183 modified "2023-10-12" @default.
• W2622813183 title "Evolutionary genomics of grape ( <i>Vitis vinifera</i> ssp. <i>vinifera</i> ) domestication" @default.
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• W2622813183 doi "https://doi.org/10.1073/pnas.1709257114" @default.
• W2622813183 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5676911" @default.
• W2622813183 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29042518" @default.
• W2622813183 hasPublicationYear "2017" @default.
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