FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2623166876> ?p ?o ?g. }

• W2623166876 abstract "Background Resistance training is a potent stimulus to induce muscle hypertrophy. Supplemental protein intake is known to enhance gains in muscle mass through activation of the mammalian target of rapamycin complex 1 (mTORC1) pathway, which initiates protein translation. While the optimal dose of high quality protein to promote post exercise anabolism in young or older men has been investigated, little is known about the minimum doses of protein required to potentiate the resistance exercise activation of anabolic signalling in middle aged men.Methods Twenty healthy men (46.3 ± 5.7 years, BMI: 23.9 ± 6.6 kg/m2) completed a single bout of unilateral resistance exercise consisting of 4 sets of leg extension and press at 80% of 1 repetition maximum. Participants were randomised to consume either formulated milk product containing 9 g milk protein (FMP) or an isoenergetic carbohydrate placebo (CHO) immediately post exercise, in a double blind fashion. A single muscle biopsy was collected at pre-exercise baseline and then bilateral biopsies were collected 90 and 240 min after beverage consumption.Results P70S6KThr389 phosphorylation was increased with exercise irrespective of group, P70S6KThr421/Ser424 was increased with exercise only in the FMP group at 240 min. Likewise, rpS6 Ser235/236 phosphorylation was increased with exercise irrespective of group, rpS6 Ser240/244 increased to a greater extent following exercise in the FMP group. mRNA expression of the amino acid transporter, LAT1/ SLC7A5 increased with both exercise and beverage consumption irrespective of group. PAT1/ SLC36A1, CAT1/ SLC7A1 and SNAT2/ SLC38A2 mRNA increased only after exercise regardless of group.Conclusions Nine grams of milk protein is sufficient to augment some measures of downstream mTORC1 signalling after resistance exercise but does not potentiate exercise induced increases in amino acid transporter expression. Formulated products containing nine grams of milk protein would be expected stimulate muscle anabolism after resistance exercise.Trial registration New Zealand Clinical Trials Registry ACTRN12615001375549. Registered: 17 December, 2015." @default.
• W2623166876 created "2017-06-15" @default.
• W2623166876 creator A5001736205 @default.
• W2623166876 creator A5007528713 @default.
• W2623166876 creator A5024381574 @default.
• W2623166876 creator A5024814922 @default.
• W2623166876 creator A5041576764 @default.
• W2623166876 creator A5041757071 @default.
• W2623166876 creator A5057663602 @default.
• W2623166876 creator A5076818269 @default.
• W2623166876 date "2017-01-03" @default.
• W2623166876 modified "2023-10-01" @default.
• W2623166876 title "Minimal dose of milk protein concentrate to enhance the anabolic signalling response to a single bout of resistance exercise; a randomised controlled trial" @default.
• W2623166876 cites W1577577364 @default.
• W2623166876 cites W1838896829 @default.
• W2623166876 cites W1895513606 @default.
• W2623166876 cites W1955249931 @default.
• W2623166876 cites W1963740134 @default.
• W2623166876 cites W1964076858 @default.
• W2623166876 cites W1965092262 @default.
• W2623166876 cites W1984915695 @default.
• W2623166876 cites W1986972592 @default.
• W2623166876 cites W1990223702 @default.
• W2623166876 cites W2017226193 @default.
• W2623166876 cites W2023981106 @default.
• W2623166876 cites W2032019813 @default.
• W2623166876 cites W2056504048 @default.
• W2623166876 cites W2062368765 @default.
• W2623166876 cites W2067767092 @default.
• W2623166876 cites W2077348052 @default.
• W2623166876 cites W2099210995 @default.
• W2623166876 cites W2100038242 @default.
• W2623166876 cites W2104063796 @default.
• W2623166876 cites W2105199683 @default.
• W2623166876 cites W2106226122 @default.
• W2623166876 cites W2111020389 @default.
• W2623166876 cites W2113082753 @default.
• W2623166876 cites W2114028666 @default.
• W2623166876 cites W2115741488 @default.
• W2623166876 cites W2116891450 @default.
• W2623166876 cites W2120035634 @default.
• W2623166876 cites W2123064842 @default.
• W2623166876 cites W2125092220 @default.
• W2623166876 cites W2130208314 @default.
• W2623166876 cites W2135419677 @default.
• W2623166876 cites W2138107413 @default.
• W2623166876 cites W2141879632 @default.
• W2623166876 cites W2146458354 @default.
• W2623166876 cites W2156860577 @default.
• W2623166876 cites W2159132862 @default.
• W2623166876 cites W2160234571 @default.
• W2623166876 cites W2162983983 @default.
• W2623166876 cites W2164863345 @default.
• W2623166876 cites W2166151826 @default.
• W2623166876 cites W2167535069 @default.
• W2623166876 cites W2257943861 @default.
• W2623166876 cites W2330580276 @default.
• W2623166876 cites W2396613666 @default.
• W2623166876 cites W2490207584 @default.
• W2623166876 cites W2607031541 @default.
• W2623166876 doi "https://doi.org/10.1186/s12970-017-0175-x" @default.
• W2623166876 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5465465" @default.
• W2623166876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28603468" @default.
• W2623166876 hasPublicationYear "2017" @default.
• W2623166876 type Work @default.
• W2623166876 sameAs 2623166876 @default.
• W2623166876 citedByCount "14" @default.
• W2623166876 countsByYear W26231668762017 @default.
• W2623166876 countsByYear W26231668762018 @default.
• W2623166876 countsByYear W26231668762019 @default.
• W2623166876 countsByYear W26231668762020 @default.
• W2623166876 crossrefType "journal-article" @default.
• W2623166876 hasAuthorship W2623166876A5001736205 @default.
• W2623166876 hasAuthorship W2623166876A5007528713 @default.
• W2623166876 hasAuthorship W2623166876A5024381574 @default.
• W2623166876 hasAuthorship W2623166876A5024814922 @default.
• W2623166876 hasAuthorship W2623166876A5041576764 @default.
• W2623166876 hasAuthorship W2623166876A5041757071 @default.
• W2623166876 hasAuthorship W2623166876A5057663602 @default.
• W2623166876 hasAuthorship W2623166876A5076818269 @default.
• W2623166876 hasBestOaLocation W26231668761 @default.
• W2623166876 hasConcept C1008401 @default.
• W2623166876 hasConcept C11960822 @default.
• W2623166876 hasConcept C126322002 @default.
• W2623166876 hasConcept C134018914 @default.
• W2623166876 hasConcept C142724271 @default.
• W2623166876 hasConcept C167414201 @default.
• W2623166876 hasConcept C204787440 @default.
• W2623166876 hasConcept C27081682 @default.
• W2623166876 hasConcept C2776214593 @default.
• W2623166876 hasConcept C2777112482 @default.
• W2623166876 hasConcept C2777188771 @default.
• W2623166876 hasConcept C2777861855 @default.
• W2623166876 hasConcept C3019424981 @default.
• W2623166876 hasConcept C55493867 @default.
• W2623166876 hasConcept C71924100 @default.
• W2623166876 hasConcept C75217442 @default.
• W2623166876 hasConcept C86803240 @default.
• W2623166876 hasConcept C98490376 @default.
• W2623166876 hasConceptScore W2623166876C1008401 @default.

• next