FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2623508712> ?p ?o ?g. }

• W2623508712 abstract "INTRODUCTION AND AIM Natural Killer (NK) cells play an important role in innate immune response to viral infections and their high proportion is situated in the liver. The aim of this study was to analyze possible relation between the expression of NK cell receptors and varied intensity of liver lesions in chronic hepatitis C (CHC) in children. MATERIAL AND METHODS Study included 105 children with CHC - 54 boys and 51 girls, age 13.62 ± 3.48 years. Blood specimens were taken at the day of the liver biopsy. Histological evaluation was performed according to METAVIR scoring system. Circulating NK cells were evaluated by flow cytometry. The results were shown as a proportion of cells expressing evaluated receptor and its' mean fluorescent intensity (MFI). RESULTS In 58 children with CHC (55.2%) significant liver fibrosis was observed ( ≥F2). Higher proportion of cells expressing CD158e inhibitory receptors was observed in the group of children with ALT > 2UNL (21.11 ± 14.60 vs. 12.22 ± 8.99%; p = 0.037). While higher proportion of cells expressing inhibitory CD158b receptor was observed in children with significant fibrosis (F ≥ 2) compared to minimal fibrosis (F < 2) - (34.14 ± 12.44 vs. 27.48 ± 8.71%; p = 0.049). Children with advanced fibrosis (F ≥ 3) had higher MFI of NK cell CD 158b receptor than children with fibrosis scored F < 3 - (5344.20 ± 3407.49 vs. 2979.67 ± 1190.64; p = 0.049). Proportion of NK cells expressing CD158b was found a predictor of significant fibrosis in univariate analysis - [OR 1.065; 95%CI (1.07-1.15); p = 0.046]. CONCLUSIONS Higher proportion of NK cells expressing inhibitory CD158b and CD158e receptors is associated with significant liver injury." @default.
• W2623508712 created "2017-06-15" @default.
• W2623508712 creator A5007340415 @default.
• W2623508712 creator A5032562828 @default.
• W2623508712 creator A5045922503 @default.
• W2623508712 creator A5065681889 @default.
• W2623508712 creator A5072436061 @default.
• W2623508712 creator A5078399050 @default.
• W2623508712 creator A5086423741 @default.
• W2623508712 date "2017-07-01" @default.
• W2623508712 modified "2023-09-26" @default.
• W2623508712 title "Expression of Natural Killer Cell Inhibitory Receptors is Associated with Significant Liver Injury in Chronic Hepatitis C in Children" @default.
• W2623508712 cites W1593550791 @default.
• W2623508712 cites W1724168744 @default.
• W2623508712 cites W1953072908 @default.
• W2623508712 cites W1969030917 @default.
• W2623508712 cites W1974091233 @default.
• W2623508712 cites W1981657600 @default.
• W2623508712 cites W2012952126 @default.
• W2623508712 cites W2022066424 @default.
• W2623508712 cites W2031235649 @default.
• W2623508712 cites W2032479841 @default.
• W2623508712 cites W2055722864 @default.
• W2623508712 cites W2058582255 @default.
• W2623508712 cites W2074544778 @default.
• W2623508712 cites W2096705269 @default.
• W2623508712 cites W2105428810 @default.
• W2623508712 cites W2114376411 @default.
• W2623508712 cites W2118623348 @default.
• W2623508712 cites W2123260081 @default.
• W2623508712 cites W2123347004 @default.
• W2623508712 cites W2131615567 @default.
• W2623508712 cites W2132268212 @default.
• W2623508712 cites W2132290252 @default.
• W2623508712 cites W2152957624 @default.
• W2623508712 cites W2162831672 @default.
• W2623508712 cites W2326495377 @default.
• W2623508712 cites W3111344083 @default.
• W2623508712 doi "https://doi.org/10.5604/01.3001.0010.0281" @default.
• W2623508712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28611271" @default.
• W2623508712 hasPublicationYear "2017" @default.
• W2623508712 type Work @default.
• W2623508712 sameAs 2623508712 @default.
• W2623508712 citedByCount "1" @default.
• W2623508712 countsByYear W26235087122020 @default.
• W2623508712 crossrefType "journal-article" @default.
• W2623508712 hasAuthorship W2623508712A5007340415 @default.
• W2623508712 hasAuthorship W2623508712A5032562828 @default.
• W2623508712 hasAuthorship W2623508712A5045922503 @default.
• W2623508712 hasAuthorship W2623508712A5065681889 @default.
• W2623508712 hasAuthorship W2623508712A5072436061 @default.
• W2623508712 hasAuthorship W2623508712A5078399050 @default.
• W2623508712 hasAuthorship W2623508712A5086423741 @default.
• W2623508712 hasBestOaLocation W26235087121 @default.
• W2623508712 hasConcept C126322002 @default.
• W2623508712 hasConcept C142724271 @default.
• W2623508712 hasConcept C170493617 @default.
• W2623508712 hasConcept C176891718 @default.
• W2623508712 hasConcept C203014093 @default.
• W2623508712 hasConcept C2775934546 @default.
• W2623508712 hasConcept C2777766500 @default.
• W2623508712 hasConcept C2780559512 @default.
• W2623508712 hasConcept C2993002077 @default.
• W2623508712 hasConcept C553184892 @default.
• W2623508712 hasConcept C71924100 @default.
• W2623508712 hasConcept C8891405 @default.
• W2623508712 hasConceptScore W2623508712C126322002 @default.
• W2623508712 hasConceptScore W2623508712C142724271 @default.
• W2623508712 hasConceptScore W2623508712C170493617 @default.
• W2623508712 hasConceptScore W2623508712C176891718 @default.
• W2623508712 hasConceptScore W2623508712C203014093 @default.
• W2623508712 hasConceptScore W2623508712C2775934546 @default.
• W2623508712 hasConceptScore W2623508712C2777766500 @default.
• W2623508712 hasConceptScore W2623508712C2780559512 @default.
• W2623508712 hasConceptScore W2623508712C2993002077 @default.
• W2623508712 hasConceptScore W2623508712C553184892 @default.
• W2623508712 hasConceptScore W2623508712C71924100 @default.
• W2623508712 hasConceptScore W2623508712C8891405 @default.
• W2623508712 hasLocation W26235087121 @default.
• W2623508712 hasOpenAccess W2623508712 @default.
• W2623508712 hasPrimaryLocation W26235087121 @default.
• W2623508712 hasRelatedWork W1783506753 @default.
• W2623508712 hasRelatedWork W2135240125 @default.
• W2623508712 hasRelatedWork W2211957714 @default.
• W2623508712 hasRelatedWork W2350282648 @default.
• W2623508712 hasRelatedWork W2363560075 @default.
• W2623508712 hasRelatedWork W2367603217 @default.
• W2623508712 hasRelatedWork W2369101863 @default.
• W2623508712 hasRelatedWork W2370070439 @default.
• W2623508712 hasRelatedWork W2379036418 @default.
• W2623508712 hasRelatedWork W2382810827 @default.
• W2623508712 hasRelatedWork W2413303973 @default.
• W2623508712 hasRelatedWork W2419338012 @default.
• W2623508712 hasRelatedWork W2778305361 @default.
• W2623508712 hasRelatedWork W2791904695 @default.
• W2623508712 hasRelatedWork W2972997716 @default.
• W2623508712 hasRelatedWork W3025343177 @default.
• W2623508712 hasRelatedWork W3030639134 @default.
• W2623508712 hasRelatedWork W3070880492 @default.
• W2623508712 hasRelatedWork W3185063456 @default.

• next