Matches in SemOpenAlex for { <https://semopenalex.org/work/W2623993141> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2623993141 abstract "We evaluated the efficacy of direct-acting antiviral (DAA) therapy in the management of renal transplant recipients with hepatitis C virus (HCV) infection. Methods: We treated two of our renal transplant recipients (Patients 1 and 2) who were HCV-RNA-(genotype 1b) positive with daclatasvir and asunaprevir. Another recipient (Patient 3), who was positive for HCV (genotype 2b), was treated with sofosbuvir and ribavirin. Patient 1 received DAA treatment following unsuccessful pegylated-interferon therapy. Prior to DAA therapy, his HCV-RNA level was 6.0 log IU/mL. After 8 weeks of treatment, DAA therapy was discontinued due to allograft dysfunction. In Patient 2, HCVRNA level before DAA therapy was 6.9 log IU/mL. In Patient 3, DAA therapy was initiated 4 months after renal transplantation, when the patient's HCV-RNA level was 7.4 log IU/mL. Results: In all cases, HCV-RNA was undetectable within 4 weeks of the initiation of DAA therapy and a sustained virological response was maintained. In Patient 1, transient deterioration of renal function gradually recovered. Patient 3 developed BK virus nephropathy (BKN) 5 weeks after completion of DAA therapy, although the relationship between DAA and BKN remains unclear. Conclusion: DAA therapy was successful in the therapeutic management of our three HCV-infected renal transplant patients. Although physicians should be aware of the possibility of complex drug interactions, DAA therapy under such conditions may provide promising short-term outcomes." @default.
- W2623993141 created "2017-06-15" @default.
- W2623993141 creator A5001155533 @default.
- W2623993141 creator A5012256492 @default.
- W2623993141 creator A5017627720 @default.
- W2623993141 creator A5035091180 @default.
- W2623993141 date "2017-01-01" @default.
- W2623993141 modified "2023-09-26" @default.
- W2623993141 title "Successful Management of Renal Transplant Recipients with Hepatitis C by Direct-Acting Antiviral Therapy: A Report on Three Cases" @default.
- W2623993141 cites W1958727566 @default.
- W2623993141 cites W1980771473 @default.
- W2623993141 cites W2000281728 @default.
- W2623993141 cites W2056058596 @default.
- W2623993141 cites W2118996012 @default.
- W2623993141 cites W2130654464 @default.
- W2623993141 cites W2164466220 @default.
- W2623993141 cites W2178839188 @default.
- W2623993141 doi "https://doi.org/10.21767/2472-5056.100032" @default.
- W2623993141 hasPublicationYear "2017" @default.
- W2623993141 type Work @default.
- W2623993141 sameAs 2623993141 @default.
- W2623993141 citedByCount "0" @default.
- W2623993141 crossrefType "journal-article" @default.
- W2623993141 hasAuthorship W2623993141A5001155533 @default.
- W2623993141 hasAuthorship W2623993141A5012256492 @default.
- W2623993141 hasAuthorship W2623993141A5017627720 @default.
- W2623993141 hasAuthorship W2623993141A5035091180 @default.
- W2623993141 hasBestOaLocation W26239931411 @default.
- W2623993141 hasConcept C126322002 @default.
- W2623993141 hasConcept C203014093 @default.
- W2623993141 hasConcept C2522874641 @default.
- W2623993141 hasConcept C2776408679 @default.
- W2623993141 hasConcept C2776455275 @default.
- W2623993141 hasConcept C2776979040 @default.
- W2623993141 hasConcept C2778390639 @default.
- W2623993141 hasConcept C2780040827 @default.
- W2623993141 hasConcept C2780303639 @default.
- W2623993141 hasConcept C2911091166 @default.
- W2623993141 hasConcept C71924100 @default.
- W2623993141 hasConcept C90924648 @default.
- W2623993141 hasConceptScore W2623993141C126322002 @default.
- W2623993141 hasConceptScore W2623993141C203014093 @default.
- W2623993141 hasConceptScore W2623993141C2522874641 @default.
- W2623993141 hasConceptScore W2623993141C2776408679 @default.
- W2623993141 hasConceptScore W2623993141C2776455275 @default.
- W2623993141 hasConceptScore W2623993141C2776979040 @default.
- W2623993141 hasConceptScore W2623993141C2778390639 @default.
- W2623993141 hasConceptScore W2623993141C2780040827 @default.
- W2623993141 hasConceptScore W2623993141C2780303639 @default.
- W2623993141 hasConceptScore W2623993141C2911091166 @default.
- W2623993141 hasConceptScore W2623993141C71924100 @default.
- W2623993141 hasConceptScore W2623993141C90924648 @default.
- W2623993141 hasIssue "02" @default.
- W2623993141 hasLocation W26239931411 @default.
- W2623993141 hasOpenAccess W2623993141 @default.
- W2623993141 hasPrimaryLocation W26239931411 @default.
- W2623993141 hasRelatedWork W2114705120 @default.
- W2623993141 hasRelatedWork W2315964890 @default.
- W2623993141 hasRelatedWork W2781686734 @default.
- W2623993141 hasRelatedWork W2797369365 @default.
- W2623993141 hasRelatedWork W2900155941 @default.
- W2623993141 hasRelatedWork W2981770118 @default.
- W2623993141 hasRelatedWork W2990662371 @default.
- W2623993141 hasRelatedWork W3000606095 @default.
- W2623993141 hasRelatedWork W3041795157 @default.
- W2623993141 hasRelatedWork W4308834824 @default.
- W2623993141 hasVolume "02" @default.
- W2623993141 isParatext "false" @default.
- W2623993141 isRetracted "false" @default.
- W2623993141 magId "2623993141" @default.
- W2623993141 workType "article" @default.