FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2624221569> ?p ?o ?g. }

• W2624221569 abstract "Abstract Understanding the relationship between neural and vascular signals is essential for interpretation of functional MRI (fMRI) results with respect to underlying neuronal activity. Simultaneously measuring neural activity using electrophysiology with fMRI has been highly valuable in elucidating the neural basis of the blood oxygenation-level dependent (BOLD) signal. However, this approach is also technically challenging due to the electromagnetic interference that is observed in electrophysiological recordings during MRI scanning. Recording optical correlates of neural activity, such as calcium signals, avoids this issue, and has opened a new avenue to simultaneously acquire neural and BOLD signals. The present study is the first to demonstrate the feasibility of simultaneously and repeatedly acquiring calcium and BOLD signals in animals using a genetically encoded calcium indicator, GCaMP6. This approach was validated with a visual stimulation experiment, during which robust increases of both calcium and BOLD signals in the superior colliculus were observed. In addition, repeated measurement in the same animal demonstrated reproducible calcium and BOLD responses to the same stimuli. Taken together, simultaneous GCaMP6-based fiber photometry and fMRI recording presents a novel, artifact-free approach to simultaneously measuring neural and fMRI signals. Furthermore, given the cell-type specificity of GCaMP6, this approach has the potential to mechanistically dissect the contributions of individual neuron populations with respect to BOLD signal, and ultimately reveal its underlying neural mechanisms." @default.
• W2624221569 created "2017-06-15" @default.
• W2624221569 creator A5017318365 @default.
• W2624221569 creator A5035611562 @default.
• W2624221569 creator A5056310334 @default.
• W2624221569 creator A5056659551 @default.
• W2624221569 date "2017-06-06" @default.
• W2624221569 modified "2023-09-28" @default.
• W2624221569 title "Simultaneous GCaMP6-based Fiber Photometry and fMRI in Rats" @default.
• W2624221569 cites W1549439691 @default.
• W2624221569 cites W1967315468 @default.
• W2624221569 cites W1977514547 @default.
• W2624221569 cites W1983924090 @default.
• W2624221569 cites W2000005600 @default.
• W2624221569 cites W2016724180 @default.
• W2624221569 cites W2016747092 @default.
• W2624221569 cites W2028184770 @default.
• W2624221569 cites W2036915958 @default.
• W2624221569 cites W2040490831 @default.
• W2624221569 cites W2058953491 @default.
• W2624221569 cites W2100524275 @default.
• W2624221569 cites W2102673550 @default.
• W2624221569 cites W2114104729 @default.
• W2624221569 cites W2129549751 @default.
• W2624221569 cites W2130390610 @default.
• W2624221569 cites W2135780113 @default.
• W2624221569 cites W2142082201 @default.
• W2624221569 cites W2148211890 @default.
• W2624221569 cites W2163274894 @default.
• W2624221569 cites W2164121465 @default.
• W2624221569 cites W2171332611 @default.
• W2624221569 cites W2259648020 @default.
• W2624221569 cites W2282633626 @default.
• W2624221569 cites W2292864446 @default.
• W2624221569 cites W244352524 @default.
• W2624221569 cites W2492138618 @default.
• W2624221569 cites W2509696888 @default.
• W2624221569 cites W2525787459 @default.
• W2624221569 doi "https://doi.org/10.1101/146779" @default.
• W2624221569 hasPublicationYear "2017" @default.
• W2624221569 type Work @default.
• W2624221569 sameAs 2624221569 @default.
• W2624221569 citedByCount "1" @default.
• W2624221569 countsByYear W26242215692017 @default.
• W2624221569 crossrefType "posted-content" @default.
• W2624221569 hasAuthorship W2624221569A5017318365 @default.
• W2624221569 hasAuthorship W2624221569A5035611562 @default.
• W2624221569 hasAuthorship W2624221569A5056310334 @default.
• W2624221569 hasAuthorship W2624221569A5056659551 @default.
• W2624221569 hasBestOaLocation W26242215691 @default.
• W2624221569 hasConcept C118403218 @default.
• W2624221569 hasConcept C153180895 @default.
• W2624221569 hasConcept C154945302 @default.
• W2624221569 hasConcept C169760540 @default.
• W2624221569 hasConcept C178790620 @default.
• W2624221569 hasConcept C185263204 @default.
• W2624221569 hasConcept C185592680 @default.
• W2624221569 hasConcept C2776032975 @default.
• W2624221569 hasConcept C2779010991 @default.
• W2624221569 hasConcept C2779226451 @default.
• W2624221569 hasConcept C2984127161 @default.
• W2624221569 hasConcept C3017539923 @default.
• W2624221569 hasConcept C41008148 @default.
• W2624221569 hasConcept C519063684 @default.
• W2624221569 hasConcept C86803240 @default.
• W2624221569 hasConceptScore W2624221569C118403218 @default.
• W2624221569 hasConceptScore W2624221569C153180895 @default.
• W2624221569 hasConceptScore W2624221569C154945302 @default.
• W2624221569 hasConceptScore W2624221569C169760540 @default.
• W2624221569 hasConceptScore W2624221569C178790620 @default.
• W2624221569 hasConceptScore W2624221569C185263204 @default.
• W2624221569 hasConceptScore W2624221569C185592680 @default.
• W2624221569 hasConceptScore W2624221569C2776032975 @default.
• W2624221569 hasConceptScore W2624221569C2779010991 @default.
• W2624221569 hasConceptScore W2624221569C2779226451 @default.
• W2624221569 hasConceptScore W2624221569C2984127161 @default.
• W2624221569 hasConceptScore W2624221569C3017539923 @default.
• W2624221569 hasConceptScore W2624221569C41008148 @default.
• W2624221569 hasConceptScore W2624221569C519063684 @default.
• W2624221569 hasConceptScore W2624221569C86803240 @default.
• W2624221569 hasLocation W26242215691 @default.
• W2624221569 hasLocation W26242215692 @default.
• W2624221569 hasOpenAccess W2624221569 @default.
• W2624221569 hasPrimaryLocation W26242215691 @default.
• W2624221569 hasRelatedWork W1089396026 @default.
• W2624221569 hasRelatedWork W2002458598 @default.
• W2624221569 hasRelatedWork W2010372342 @default.
• W2624221569 hasRelatedWork W2060477798 @default.
• W2624221569 hasRelatedWork W2080478523 @default.
• W2624221569 hasRelatedWork W2464433012 @default.
• W2624221569 hasRelatedWork W2532155896 @default.
• W2624221569 hasRelatedWork W2617929785 @default.
• W2624221569 hasRelatedWork W2763956238 @default.
• W2624221569 hasRelatedWork W2777254851 @default.
• W2624221569 hasRelatedWork W2795327979 @default.
• W2624221569 hasRelatedWork W2804686809 @default.
• W2624221569 hasRelatedWork W2883315705 @default.
• W2624221569 hasRelatedWork W2898378669 @default.
• W2624221569 hasRelatedWork W2902790401 @default.
• W2624221569 hasRelatedWork W2916025406 @default.

• next