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- W2624842904 abstract "To address the effect of hGGO1 (rs1052133) gene polymorphism on the risk of breast cancer, a meta-analysis was performed. We pooled adjusted odds ratios (OR) as overall and three subgroups (menopausal status, ethnicity, and study setting). In overall analysis, we found a significant association when the model of inheritance was homozygote (pooled OR 1.14; 95% CI 1.01, 1.29). Subgroup analysis showed significant association for homozygote genetic models among postmenopause women (OR 1.23; 95% CI 1.01, 1.49) and Asian population (OR 1.17; 95% CI 1.01, 1.35). This study suggested that the carrier of Ser326Cys polymorphism of hOGG1, Cys/Cys vs Ser/Ser, are at higher risk for breast cancer, independent of other hormonal and environmental risk factors." @default.
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- W2624842904 date "2017-06-13" @default.
- W2624842904 modified "2023-10-16" @default.
- W2624842904 title "hOGG1 gene polymorphism and breast cancer risk: A systematic review and meta-analysis study" @default.
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- W2624842904 doi "https://doi.org/10.1111/tbj.12842" @default.
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