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• W2625077721 endingPage "101042831770576" @default.
• W2625077721 startingPage "101042831770576" @default.
• W2625077721 abstract "Dysregulation in microRNA expression is a common feature in colorectal cancer. Due to the inconsistent results regarding serum miR-92a expression pattern and the insufficient studies on serum miR-375 and miR-760, we aimed in this study to investigate their expression profile and diagnostic and prognostic power in Egyptian colorectal cancer patients. The expression profile of miR-92a, miR-375, and miR-760 was determined in the sera of 64 colorectal cancer patients using quantitative real-time reverse transcription polymerase chain reaction in comparison to 27 healthy control subjects. The expression fold change of the studied microRNAs was correlated with patients' clinicopathological features. Receiver operating characteristic curve analysis was done to determine the role of these microRNAs in colorectal cancer diagnosis and follow-up according to the yielded area under the curve. The expression pattern of miR-92a was significantly upregulated (3.38 ± 2.52, p < 0.0001), while both of miR-375 and 760 were significantly downregulated (-1.250 ± 1.80, p< 0.0001; -1.710 ± 1.88, p < 0.0001, respectively) in colorectal cancer than the control. MiR-92a was positively correlated ( r = 0.671, p = 0.0001), while miR-375 and miR-760 were inversely correlated ( r = -0.414, p = 0.001; r = -0.644, p = 0.0001) with advanced colorectal cancer stages. Receiver operating characteristic curve analysis disclosed the highest diagnostic potential for miR-760 to discriminate colorectal cancer patients and early-stage colorectal cancer from the control (area under the curve = 0.922 and 0.875, respectively), while the highest prognostic potential for discrimination between colorectal cancer stages was for miR-92a. In conclusion, serum level of miR-92a, miR-375, and miR-760 may serve as biomarkers of colorectal cancer in Egyptian patients with high diagnostic power for miR-760 and high prognostic power for miR-92a." @default.
• W2625077721 created "2017-06-23" @default.
• W2625077721 creator A5024166317 @default.
• W2625077721 creator A5026961749 @default.
• W2625077721 creator A5050403847 @default.
• W2625077721 creator A5060361437 @default.
• W2625077721 date "2017-06-01" @default.
• W2625077721 modified "2023-10-15" @default.
• W2625077721 title "The expression profiling of serum miR-92a, miR-375, and miR-760 in colorectal cancer: An Egyptian study" @default.
• W2625077721 cites W1017675820 @default.
• W2625077721 cites W1146321858 @default.
• W2625077721 cites W1496125310 @default.
• W2625077721 cites W1499305226 @default.
• W2625077721 cites W1607015107 @default.
• W2625077721 cites W1757407923 @default.
• W2625077721 cites W1766127718 @default.
• W2625077721 cites W1884243320 @default.
• W2625077721 cites W1963912082 @default.
• W2625077721 cites W1969188594 @default.
• W2625077721 cites W1971115903 @default.
• W2625077721 cites W1972614147 @default.
• W2625077721 cites W1978637534 @default.
• W2625077721 cites W1981055638 @default.
• W2625077721 cites W1981170620 @default.
• W2625077721 cites W1985126068 @default.
• W2625077721 cites W1987237070 @default.
• W2625077721 cites W1990868219 @default.
• W2625077721 cites W1995555978 @default.
• W2625077721 cites W1996963134 @default.
• W2625077721 cites W1998351130 @default.
• W2625077721 cites W1999732172 @default.
• W2625077721 cites W2002168324 @default.
• W2625077721 cites W2008577060 @default.
• W2625077721 cites W2009743352 @default.
• W2625077721 cites W2013233216 @default.
• W2625077721 cites W2014476374 @default.
• W2625077721 cites W2028831862 @default.
• W2625077721 cites W2031450658 @default.
• W2625077721 cites W2044073319 @default.
• W2625077721 cites W2044782990 @default.
• W2625077721 cites W2045048675 @default.
• W2625077721 cites W2048984063 @default.
• W2625077721 cites W2050829849 @default.
• W2625077721 cites W2051968829 @default.
• W2625077721 cites W2052974657 @default.
• W2625077721 cites W2061287632 @default.
• W2625077721 cites W2061515918 @default.
• W2625077721 cites W2079355514 @default.
• W2625077721 cites W2080092755 @default.
• W2625077721 cites W2081705769 @default.
• W2625077721 cites W2082231527 @default.
• W2625077721 cites W2083911442 @default.
• W2625077721 cites W2084825118 @default.
• W2625077721 cites W2089737806 @default.
• W2625077721 cites W2091747532 @default.
• W2625077721 cites W2094043646 @default.
• W2625077721 cites W2101666723 @default.
• W2625077721 cites W2102628051 @default.
• W2625077721 cites W2107277218 @default.
• W2625077721 cites W2113807582 @default.
• W2625077721 cites W2115093090 @default.
• W2625077721 cites W2122014435 @default.
• W2625077721 cites W2123851279 @default.
• W2625077721 cites W2126934643 @default.
• W2625077721 cites W2135613885 @default.
• W2625077721 cites W2139528114 @default.
• W2625077721 cites W2140245250 @default.
• W2625077721 cites W2146157095 @default.
• W2625077721 cites W2149966907 @default.
• W2625077721 cites W2155233355 @default.
• W2625077721 cites W2162865290 @default.
• W2625077721 cites W2163025807 @default.
• W2625077721 cites W2163718382 @default.
• W2625077721 cites W2202961459 @default.
• W2625077721 cites W2256104903 @default.
• W2625077721 cites W2268148666 @default.
• W2625077721 cites W2279715668 @default.
• W2625077721 cites W2290979890 @default.
• W2625077721 cites W2292589236 @default.
• W2625077721 cites W2295085960 @default.
• W2625077721 cites W2340473927 @default.
• W2625077721 cites W2398542230 @default.
• W2625077721 cites W2401287460 @default.
• W2625077721 cites W2412364864 @default.
• W2625077721 cites W2493260470 @default.
• W2625077721 cites W2517575491 @default.
• W2625077721 cites W2542315333 @default.
• W2625077721 cites W2547126613 @default.
• W2625077721 cites W3192832044 @default.
• W2625077721 doi "https://doi.org/10.1177/1010428317705765" @default.
• W2625077721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28618945" @default.
• W2625077721 hasPublicationYear "2017" @default.
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