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• W2625645112 abstract "<b><i>Background/Aims:</i></b> Polyethylenimine-coated polyacrylonitrile (AN69ST) membrane is expected to improve the outcomes of critically ill patients treated by continuous renal replacement therapy (CRRT). <b><i>Methods:</i></b> Using a Japanese health insurance claim database, we identified adult patients receiving CRRT in intensive care units (ICUs) from April 2014 to October 2015. We used a multivariable logistic regression model to assess in-hospital mortality and Fine and Gray's proportional subhazards model to assess the ICU length of stay (ICU-LOS) accounting for the competing risks. <b><i>Results:</i></b> Of 2,469 ICU patients, 156 were treated by AN69ST membrane. Crude in-hospital mortality was 50.0% in the AN69ST group and 54.0% in the non-AN69ST group. Adjusted odds ratio (OR) of AN69ST membrane use for in-hospital mortality was 0.65 (95% CI 0.45-0.93). The use of AN69ST membrane was also independently associated with shorter ICU-LOS. <b><i>Conclusion:</i></b> This retrospective observational study suggested that CRRT with AN69ST membrane might be associated with better in-hospital outcomes." @default.
• W2625645112 created "2017-06-23" @default.
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• W2625645112 date "2017-01-01" @default.
• W2625645112 modified "2023-10-03" @default.
• W2625645112 title "Associations of Polyethylenimine-Coated AN69ST Membrane in Continuous Renal Replacement Therapy with the Intensive Care Outcomes: Observations from a Claims Database from Japan" @default.
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• W2625645112 doi "https://doi.org/10.1159/000476052" @default.
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