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- W262606656 abstract "Abstract : This study is assessing the effects in guinea pigs of repeated low-dose exposure to the nerve agent sarin. Preliminary results suggest no effects of either repeated 0.2 or 0.4 X LD50 sarin exposure (compared with saline) on body weight or temperature, general physical signs, flinch threshold or activity level, or on EEG activity. In contrast, RBC cholinesterase levels dropped to 20% of baseline following the tenth exposure in the 0.4 group. Since this study is ongoing, data from receptor binding and brain cholinesterase assays and histopathology are still being collected and analyzed, and may be influenced by the dramatic changes in cholinesterase activity." @default.
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- W262606656 date "2002-01-01" @default.
- W262606656 modified "2023-09-27" @default.
- W262606656 title "The Potential Neurotoxic Effects of Low-Dose Sarin Exposure in a Guinea Pig Model" @default.
- W262606656 hasPublicationYear "2002" @default.
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