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- W2626082949 abstract "The present study investigated the anti‑aging effects of pomegranate juice concentrated powder (PCP) in hairless mice following 15 weeks of UVB irradiation (three times a week; 0.18 J/cm2). Skin moisturizing effects were evaluated through skin water, collagen type I and hyaluronan contents, as well as collagen type I and hyaluronan synthesis-related transcript levels. Wrinkle formation and edema scores (skin weights) were also assessed, along with skin matrix metalloproteinase (MMP)‑1, MMP‑9 and MMP‑13 transcript levels. To determine the anti‑inflammatory effects of PCP, myeloperoxidase (MPO) activity, interleukin (IL)‑1β and IL‑10 contents were observed. Caspase‑3 and cleaved poly(ADP-ribose) polymerase (PARP) were used as an apoptotic index in epidermal keratinocytes. To determine the anti‑oxidative effects of PCP, nitrotyrosine and 4‑hydroxynonenal immunoreactive cells were detected and glutathione (GSH) content, malondialdehyde levels, superoxide anion production, Nox2, and GSH reductase mRNA expression were all measured. The results indicated that skin wrinkles induced by photoaging were significantly reduced by PCP, whereas skin water contents, collagen type I and hyaluronan contents all increased. Furthermore, IL‑1β levels in the PCP‑treated groups were lower than those in the UVB‑exposed control group. UVB‑induced GSH depletion was also inhibited by PCP. Taken together, the results of the current study suggest that PCP has favorable protective effects against UVB‑induced photoaging through anti‑apoptotic effects, MMP activity inhibition and ECM (COL1 and hyaluronan) synthesis‑related moisturizing, anti‑inflammatory and anti-oxidative effects." @default.
- W2626082949 created "2017-06-23" @default.
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- W2626082949 date "2017-06-16" @default.
- W2626082949 modified "2023-09-30" @default.
- W2626082949 title "Beneficial effects of dried pomegranate juice concentrated powder on ultraviolet B-induced skin photoaging in hairless mice" @default.
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- W2626082949 cites W1891389145 @default.
- W2626082949 cites W1967270772 @default.
- W2626082949 cites W1969603048 @default.
- W2626082949 cites W1969618525 @default.
- W2626082949 cites W1974398142 @default.
- W2626082949 cites W1979685326 @default.
- W2626082949 cites W1980166485 @default.
- W2626082949 cites W1984885413 @default.
- W2626082949 cites W1985208889 @default.
- W2626082949 cites W1994972521 @default.
- W2626082949 cites W1997114069 @default.
- W2626082949 cites W1998750632 @default.
- W2626082949 cites W2000147012 @default.
- W2626082949 cites W2000397596 @default.
- W2626082949 cites W2005205647 @default.
- W2626082949 cites W2005745212 @default.
- W2626082949 cites W2008820810 @default.
- W2626082949 cites W2013383709 @default.
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- W2626082949 cites W2017802466 @default.
- W2626082949 cites W2029559735 @default.
- W2626082949 cites W2031017058 @default.
- W2626082949 cites W2031468866 @default.
- W2626082949 cites W2044586125 @default.
- W2626082949 cites W2047420559 @default.
- W2626082949 cites W2047990479 @default.
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- W2626082949 cites W2052115777 @default.
- W2626082949 cites W2053483375 @default.
- W2626082949 cites W2054697466 @default.
- W2626082949 cites W2057458129 @default.
- W2626082949 cites W2060256533 @default.
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- W2626082949 cites W2064753339 @default.
- W2626082949 cites W2068388923 @default.
- W2626082949 cites W2084141237 @default.
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- W2626082949 cites W2141462478 @default.
- W2626082949 cites W2144210822 @default.
- W2626082949 cites W2147089380 @default.
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- W2626082949 doi "https://doi.org/10.3892/etm.2017.4626" @default.
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- W2626082949 hasPublicationYear "2017" @default.
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