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• W2626381041 endingPage "589" @default.
• W2626381041 startingPage "581" @default.
• W2626381041 abstract "The tumor suppressor phosphatase and tensin homolog (PTEN) is a lipid and protein phosphatase that is able to antagonize the PI3K/AKT pathway and inhibit tumor growth. PTEN also possesses phosphatase-independent functions. Genetic alterations of PTEN may lead to the deregulation of cell proliferation, survival, differentiation, energy metabolism and cellular architecture and mobility. Although the role of PTEN in tumor suppression is extensively documented and well established, the evidence for its roles in immunity did not start to accumulate until recently. In this review, we will focus on the newly discovered functions of PTEN in the regulation of innate and adaptive immunity, including antiviral responses." @default.
• W2626381041 created "2017-06-23" @default.
• W2626381041 creator A5023916267 @default.
• W2626381041 creator A5082643397 @default.
• W2626381041 date "2017-06-26" @default.
• W2626381041 modified "2023-10-13" @default.
• W2626381041 title "The functions of tumor suppressor PTEN in innate and adaptive immunity" @default.
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• W2626381041 doi "https://doi.org/10.1038/cmi.2017.30" @default.
• W2626381041 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5520418" @default.
• W2626381041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28603282" @default.
• W2626381041 hasPublicationYear "2017" @default.
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