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• W2626974295 abstract "Magnetic nanoparticles can be used in different areas of biology. It is therefore important to know the effects of such nanomaterials on germline cells as they may traverse the blood-testis barrier. This work aimed to evaluate the response of bull sperm after exposure to a magnetic fluid containing DMSA-coated maghemite nanoparticles (MNP-DMSA) in order to determine nanotoxicity. Bull sperm was incubated with MNP-DMSA at final concentrations of 0.06, 0.03 or 0.015 mg Fe/mL. Sperm kinetics, plasma membrane integrity and acrosome reaction were evaluated over a 4 h incubation period. The sperm cells were also evaluated by transmission electron microscopy. Exposure of bull sperm to MNP-DMSA did not affect sperm kinetics or integrity. Neither ultrastructural damage of sperm cells nor uptake of nanoparticles by the spermatozoa was observed. In conclusion, MNP-DMSA does not affect sperm function or structure under the conditions tested." @default.
• W2626974295 created "2017-06-23" @default.
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• W2626974295 date "2017-06-28" @default.
• W2626974295 modified "2023-10-13" @default.
• W2626974295 title "<i>In vitro</i> exposure of bull sperm cells to DMSA-coated maghemite nanoparticles does not affect cell functionality or structure" @default.
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• W2626974295 doi "https://doi.org/10.1080/02656736.2017.1341646" @default.
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