Matches in SemOpenAlex for { <https://semopenalex.org/work/W2627059495> ?p ?o ?g. }
- W2627059495 endingPage "336" @default.
- W2627059495 startingPage "331" @default.
- W2627059495 abstract "The aim of this experimental study was to investigate the impact of HA-CS-NAG compound (hyaluronate, sodium chondroitin sulfate, N-acetyl-d-glucosamine) on the quality of repair tissue after micro-fracture and to compare it with HA (hyaluronat), in a rat full-thickness chondral defect model.Full-thickness chondral defects were created in a non-weight bearing area by using a handle 2.7-mm drill bit, in the right knees of 33 Sprague-Dawley rats. Each specimen then underwent micro-fracture using a needle. Two weeks after surgery, 3 groups were randomly formed among the rats (n = 33). In Group 1, 0.2 mL of sterile saline solution (0.9%) was injected. In Group 2, 0.2 mL HA with a mean molecular weight of 1.2 Mda was injected. In Group 3, 0.2 mL of HA-CS-NAG compound (hyaluronate, sodium chondroitin sulfate, N-acetyl-d-glucosamine) was injected. The injections were applied on the 14th, the 21st and the 28th postoperative days. All rats were sacrificed on the 42nd postoperative day. Histological analysis of the repair tissue was performed for each specimen by two blinded observers using Wakitani scoring system.There was significantly improved repair tissue in both Group 3 and Group 2 when compared with Group 1. Group 3 showed statistically significant improvement in terms of 'cell morphology' and 'integration of donor with host' when compared to Group 2 (p < 0.001).Intra-articular injection of HA-CS-NAG compound after micro-fracture results in significantly improved repair tissue in rats' chondral defects when compared to HA regarding the donor integration and cell morphology." @default.
- W2627059495 created "2017-06-23" @default.
- W2627059495 creator A5002588103 @default.
- W2627059495 creator A5009255086 @default.
- W2627059495 creator A5025889549 @default.
- W2627059495 creator A5064050066 @default.
- W2627059495 creator A5064612402 @default.
- W2627059495 creator A5083687716 @default.
- W2627059495 date "2017-07-01" @default.
- W2627059495 modified "2023-10-11" @default.
- W2627059495 title "The comparison of the effects of a novel hydrogel compound and traditional hyaluronate following micro-fracture procedure in a rat full-thickness chondral defect model" @default.
- W2627059495 cites W1522229466 @default.
- W2627059495 cites W1678513801 @default.
- W2627059495 cites W1763533364 @default.
- W2627059495 cites W1969768125 @default.
- W2627059495 cites W1979653063 @default.
- W2627059495 cites W1984390800 @default.
- W2627059495 cites W1984664272 @default.
- W2627059495 cites W1999014699 @default.
- W2627059495 cites W2007251381 @default.
- W2627059495 cites W2013768928 @default.
- W2627059495 cites W2021570058 @default.
- W2627059495 cites W2022804076 @default.
- W2627059495 cites W2023165395 @default.
- W2627059495 cites W2035198182 @default.
- W2627059495 cites W2042788359 @default.
- W2627059495 cites W2051446426 @default.
- W2627059495 cites W2054191814 @default.
- W2627059495 cites W2072556794 @default.
- W2627059495 cites W2075467729 @default.
- W2627059495 cites W2089417526 @default.
- W2627059495 cites W2090977911 @default.
- W2627059495 cites W2091302042 @default.
- W2627059495 cites W2092983224 @default.
- W2627059495 cites W2116272364 @default.
- W2627059495 cites W2127616408 @default.
- W2627059495 cites W2129573593 @default.
- W2627059495 cites W2130513475 @default.
- W2627059495 cites W2132865989 @default.
- W2627059495 cites W2143746784 @default.
- W2627059495 cites W2145932168 @default.
- W2627059495 cites W2148734048 @default.
- W2627059495 cites W2149130601 @default.
- W2627059495 cites W2156334389 @default.
- W2627059495 cites W2161739926 @default.
- W2627059495 cites W2197016826 @default.
- W2627059495 cites W2407986653 @default.
- W2627059495 cites W3151290442 @default.
- W2627059495 cites W4253987619 @default.
- W2627059495 cites W2344413160 @default.
- W2627059495 doi "https://doi.org/10.1016/j.aott.2017.04.001" @default.
- W2627059495 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6197372" @default.
- W2627059495 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28622807" @default.
- W2627059495 hasPublicationYear "2017" @default.
- W2627059495 type Work @default.
- W2627059495 sameAs 2627059495 @default.
- W2627059495 citedByCount "6" @default.
- W2627059495 countsByYear W26270594952018 @default.
- W2627059495 countsByYear W26270594952019 @default.
- W2627059495 countsByYear W26270594952021 @default.
- W2627059495 countsByYear W26270594952022 @default.
- W2627059495 crossrefType "journal-article" @default.
- W2627059495 hasAuthorship W2627059495A5002588103 @default.
- W2627059495 hasAuthorship W2627059495A5009255086 @default.
- W2627059495 hasAuthorship W2627059495A5025889549 @default.
- W2627059495 hasAuthorship W2627059495A5064050066 @default.
- W2627059495 hasAuthorship W2627059495A5064612402 @default.
- W2627059495 hasAuthorship W2627059495A5083687716 @default.
- W2627059495 hasBestOaLocation W26270594951 @default.
- W2627059495 hasConcept C105702510 @default.
- W2627059495 hasConcept C126322002 @default.
- W2627059495 hasConcept C126894567 @default.
- W2627059495 hasConcept C141071460 @default.
- W2627059495 hasConcept C153074725 @default.
- W2627059495 hasConcept C185592680 @default.
- W2627059495 hasConcept C2777397205 @default.
- W2627059495 hasConcept C2777529286 @default.
- W2627059495 hasConcept C2777917749 @default.
- W2627059495 hasConcept C2778125326 @default.
- W2627059495 hasConcept C2779553658 @default.
- W2627059495 hasConcept C2989005 @default.
- W2627059495 hasConcept C55493867 @default.
- W2627059495 hasConcept C71924100 @default.
- W2627059495 hasConcept C8337478 @default.
- W2627059495 hasConceptScore W2627059495C105702510 @default.
- W2627059495 hasConceptScore W2627059495C126322002 @default.
- W2627059495 hasConceptScore W2627059495C126894567 @default.
- W2627059495 hasConceptScore W2627059495C141071460 @default.
- W2627059495 hasConceptScore W2627059495C153074725 @default.
- W2627059495 hasConceptScore W2627059495C185592680 @default.
- W2627059495 hasConceptScore W2627059495C2777397205 @default.
- W2627059495 hasConceptScore W2627059495C2777529286 @default.
- W2627059495 hasConceptScore W2627059495C2777917749 @default.
- W2627059495 hasConceptScore W2627059495C2778125326 @default.
- W2627059495 hasConceptScore W2627059495C2779553658 @default.
- W2627059495 hasConceptScore W2627059495C2989005 @default.
- W2627059495 hasConceptScore W2627059495C55493867 @default.
- W2627059495 hasConceptScore W2627059495C71924100 @default.