Matches in SemOpenAlex for { <https://semopenalex.org/work/W263033747> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W263033747 endingPage "8" @default.
- W263033747 startingPage "811" @default.
- W263033747 abstract "Mouse monoclonal antibodies (MoAbs) of different classes and subclasses directed against antigens not expected to be present on human cells have been screened by indirect immunofluorescence using flow cytometry for binding to human non-lymphocytic leukaemic cells and normal peripheral blood leucocytes. Antibodies of the IgG2a and IgG3 subclass, but not of the IgG1, IgG2b or IgM class bound to the blast cell and monocyte populations in a peripheral blood mononuclear cell preparation from a patient with acute myelomonocytic leukaemia. F(ab')2 fragments of an anti-salmonella antibody of IgG2a subclass failed to bind, indicating that the results were not due to cross-reactivity with antigens of the cell membrane, thus implicating the Fc region in binding. Furthermore, binding was partly blocked by inclusion of 10% heat-inactivated normal rabbit serum in the assays. IgG2a bound to varying degrees to the leukaemic cell populations in seven of the nine non-lymphocytic leukaemic specimens tested, but no binding to normal peripheral blood mononuclear cells or granulocytes was detected. The results emphasize the importance of including appropriate controls when screening MoAbs for binding to various types of human cells." @default.
- W263033747 created "2016-06-24" @default.
- W263033747 creator A5044229896 @default.
- W263033747 creator A5046832327 @default.
- W263033747 date "1983-12-01" @default.
- W263033747 modified "2023-10-18" @default.
- W263033747 title "Binding of mouse monoclonal antibodies to human leukaemic cells via the Fc receptor: a possible source of 'false positive' reactions in specificity screening." @default.
- W263033747 cites W117141673 @default.
- W263033747 cites W1502226188 @default.
- W263033747 cites W1963535965 @default.
- W263033747 cites W1977461031 @default.
- W263033747 cites W1983047335 @default.
- W263033747 cites W2009811622 @default.
- W263033747 cites W2024642713 @default.
- W263033747 cites W2030522563 @default.
- W263033747 cites W2076426515 @default.
- W263033747 cites W2078444872 @default.
- W263033747 cites W2125724491 @default.
- W263033747 cites W2141715517 @default.
- W263033747 cites W295743176 @default.
- W263033747 cites W6934190 @default.
- W263033747 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1536158" @default.
- W263033747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6580981" @default.
- W263033747 hasPublicationYear "1983" @default.
- W263033747 type Work @default.
- W263033747 sameAs 263033747 @default.
- W263033747 citedByCount "12" @default.
- W263033747 crossrefType "journal-article" @default.
- W263033747 hasAuthorship W263033747A5044229896 @default.
- W263033747 hasAuthorship W263033747A5046832327 @default.
- W263033747 hasConcept C137061746 @default.
- W263033747 hasConcept C147483822 @default.
- W263033747 hasConcept C153911025 @default.
- W263033747 hasConcept C159654299 @default.
- W263033747 hasConcept C202751555 @default.
- W263033747 hasConcept C203014093 @default.
- W263033747 hasConcept C2776194381 @default.
- W263033747 hasConcept C2778236600 @default.
- W263033747 hasConcept C2779931124 @default.
- W263033747 hasConcept C2781184567 @default.
- W263033747 hasConcept C542903549 @default.
- W263033747 hasConcept C553184892 @default.
- W263033747 hasConcept C55493867 @default.
- W263033747 hasConcept C86803240 @default.
- W263033747 hasConceptScore W263033747C137061746 @default.
- W263033747 hasConceptScore W263033747C147483822 @default.
- W263033747 hasConceptScore W263033747C153911025 @default.
- W263033747 hasConceptScore W263033747C159654299 @default.
- W263033747 hasConceptScore W263033747C202751555 @default.
- W263033747 hasConceptScore W263033747C203014093 @default.
- W263033747 hasConceptScore W263033747C2776194381 @default.
- W263033747 hasConceptScore W263033747C2778236600 @default.
- W263033747 hasConceptScore W263033747C2779931124 @default.
- W263033747 hasConceptScore W263033747C2781184567 @default.
- W263033747 hasConceptScore W263033747C542903549 @default.
- W263033747 hasConceptScore W263033747C553184892 @default.
- W263033747 hasConceptScore W263033747C55493867 @default.
- W263033747 hasConceptScore W263033747C86803240 @default.
- W263033747 hasIssue "3" @default.
- W263033747 hasLocation W2630337471 @default.
- W263033747 hasOpenAccess W263033747 @default.
- W263033747 hasPrimaryLocation W2630337471 @default.
- W263033747 hasRelatedWork W1977276363 @default.
- W263033747 hasRelatedWork W2024642713 @default.
- W263033747 hasRelatedWork W2037509311 @default.
- W263033747 hasRelatedWork W2069088488 @default.
- W263033747 hasRelatedWork W2073262237 @default.
- W263033747 hasRelatedWork W2094194110 @default.
- W263033747 hasRelatedWork W2119760056 @default.
- W263033747 hasRelatedWork W2196101296 @default.
- W263033747 hasRelatedWork W2410111069 @default.
- W263033747 hasRelatedWork W2416917507 @default.
- W263033747 hasVolume "54" @default.
- W263033747 isParatext "false" @default.
- W263033747 isRetracted "false" @default.
- W263033747 magId "263033747" @default.
- W263033747 workType "article" @default.