Matches in SemOpenAlex for { <https://semopenalex.org/work/W2632077510> ?p ?o ?g. }
- W2632077510 abstract "Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However, owing to the low radiation absorption of tumors, high doses of ionizing radiations are often needed during RT, leading to severe damages to normal tissues adjacent to tumors. Meanwhile, the RT efficacies are limited by different mechanisms, among which the tumor hypoxia‐associated radiation resistance is a well‐known one, as there exists hypoxia inside most solid tumors while oxygen is essential to enhance radiation‐induced DNA damages. With the development in nanotechnology, there have been great interests in using nanomedicine strategies to enhance radiation responses of tumors. Nanomaterials containing high‐Z elements to absorb radiation rays (e.g. X‐ray) can act as radio‐sensitizers to deposit radiation energy within tumors and promote treatment efficacy. Nanoscale carriers are able to deliver therapeutic radioisotopes into tumors for internal RIT, or chemotherapeutic drugs for synergistically combined chemo‐radiotherapy. As uncovered in recent studies, the tumor microenvironment could be modulated by various nanomedicine approaches to overcome hypoxia‐associated radiation resistance. Herein, the authors will summarize the applications of nanomedicine for RT cancer treatment, and pay particular attention to the latest development of ‘advanced materials' for enhanced cancer RT." @default.
- W2632077510 created "2017-06-30" @default.
- W2632077510 creator A5020513637 @default.
- W2632077510 creator A5028364292 @default.
- W2632077510 creator A5045776022 @default.
- W2632077510 creator A5072979414 @default.
- W2632077510 creator A5084452813 @default.
- W2632077510 date "2017-06-23" @default.
- W2632077510 modified "2023-10-09" @default.
- W2632077510 title "Emerging Nanotechnology and Advanced Materials for Cancer Radiation Therapy" @default.
- W2632077510 cites W1008653395 @default.
- W2632077510 cites W1190594965 @default.
- W2632077510 cites W1448931496 @default.
- W2632077510 cites W1480745270 @default.
- W2632077510 cites W1482725337 @default.
- W2632077510 cites W1494375241 @default.
- W2632077510 cites W1507021713 @default.
- W2632077510 cites W1527151869 @default.
- W2632077510 cites W1527954946 @default.
- W2632077510 cites W1566032777 @default.
- W2632077510 cites W1568224946 @default.
- W2632077510 cites W1608375682 @default.
- W2632077510 cites W1787328417 @default.
- W2632077510 cites W1834322579 @default.
- W2632077510 cites W1838570471 @default.
- W2632077510 cites W1839776650 @default.
- W2632077510 cites W1855057195 @default.
- W2632077510 cites W1868554855 @default.
- W2632077510 cites W1874076185 @default.
- W2632077510 cites W1878799800 @default.
- W2632077510 cites W1897423949 @default.
- W2632077510 cites W1906825328 @default.
- W2632077510 cites W1912124796 @default.
- W2632077510 cites W1924811449 @default.
- W2632077510 cites W1937121752 @default.
- W2632077510 cites W1942992880 @default.
- W2632077510 cites W1963635535 @default.
- W2632077510 cites W1963901824 @default.
- W2632077510 cites W1964308712 @default.
- W2632077510 cites W1966597723 @default.
- W2632077510 cites W1967452921 @default.
- W2632077510 cites W1969592847 @default.
- W2632077510 cites W1969790128 @default.
- W2632077510 cites W1970646360 @default.
- W2632077510 cites W1970824089 @default.
- W2632077510 cites W1971464137 @default.
- W2632077510 cites W1976385056 @default.
- W2632077510 cites W1977020389 @default.
- W2632077510 cites W1978762833 @default.
- W2632077510 cites W1978894954 @default.
- W2632077510 cites W1979372884 @default.
- W2632077510 cites W1981128935 @default.
- W2632077510 cites W1982654262 @default.
- W2632077510 cites W1983990921 @default.
- W2632077510 cites W1984804948 @default.
- W2632077510 cites W1984953757 @default.
- W2632077510 cites W1985334660 @default.
- W2632077510 cites W1986314614 @default.
- W2632077510 cites W1986441241 @default.
- W2632077510 cites W1988074177 @default.
- W2632077510 cites W1990101064 @default.
- W2632077510 cites W1990274185 @default.
- W2632077510 cites W1990497426 @default.
- W2632077510 cites W1990906371 @default.
- W2632077510 cites W1991908666 @default.
- W2632077510 cites W1994423628 @default.
- W2632077510 cites W1994641752 @default.
- W2632077510 cites W1994787250 @default.
- W2632077510 cites W1995586545 @default.
- W2632077510 cites W1996830477 @default.
- W2632077510 cites W1997506303 @default.
- W2632077510 cites W1998328526 @default.
- W2632077510 cites W1999456866 @default.
- W2632077510 cites W1999588611 @default.
- W2632077510 cites W1999626926 @default.
- W2632077510 cites W2000270628 @default.
- W2632077510 cites W2001700365 @default.
- W2632077510 cites W2002064890 @default.
- W2632077510 cites W2002321093 @default.
- W2632077510 cites W2002686259 @default.
- W2632077510 cites W2003315550 @default.
- W2632077510 cites W2003851720 @default.
- W2632077510 cites W2007062068 @default.
- W2632077510 cites W2007106984 @default.
- W2632077510 cites W2007479294 @default.
- W2632077510 cites W2007688194 @default.
- W2632077510 cites W2011875227 @default.
- W2632077510 cites W2013645973 @default.
- W2632077510 cites W2014361243 @default.
- W2632077510 cites W2015223548 @default.
- W2632077510 cites W2016664700 @default.
- W2632077510 cites W2018588081 @default.
- W2632077510 cites W2020398834 @default.
- W2632077510 cites W2020538451 @default.
- W2632077510 cites W2020825769 @default.
- W2632077510 cites W2022139266 @default.
- W2632077510 cites W2024601575 @default.
- W2632077510 cites W2026757562 @default.
- W2632077510 cites W2029549646 @default.
- W2632077510 cites W2029890534 @default.