Matches in SemOpenAlex for { <https://semopenalex.org/work/W2636639861> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2636639861 abstract "Introduction Syphilis is a multistage STI caused by Treponema pallidum. The classic lesion of primary syphilis is a chancre – a single, painless, indurated ulcer with a clean base. The number of cases is on the rise, and it has been historically difficult to diagnose due to its variable presentation, requiring clinical correlation and multiple investigations. PCR use has increased recently in investigation of these ulcers. However, how crucial is PCR testing in primary syphilis, when cheaper investigations can lead to a diagnosis? Methods Investigation results were collected from 58 patients presenting between January and December 2015 who were treated for primary syphilis, including presentation, serology and PCR status. How they were diagnosed as having primary syphilis was noted and whether this was on presentation, follow up or via PCR. Results 47 patients had a positive PCR, 11 patients had a negative PCR but were treated for primary syphilis. We found 3 patients would have not been picked up as having primary syphilis if there was no PCR performed. The sensitivity and specificity of Treponema pallidum PCR was 81% and 100% respectively. Discussion PCR was essential in diagnosing 3 patients with syphilis who would have been missed, therefore PCR is a crucial tool in contributing to the diagnosis of primary syphilis. The potential implications of missing syphilis diagnosis are serious, as patients can develop progressive disease and unknowingly affect sexual partners." @default.
- W2636639861 created "2017-06-30" @default.
- W2636639861 creator A5023039237 @default.
- W2636639861 creator A5046091213 @default.
- W2636639861 creator A5079816611 @default.
- W2636639861 date "2017-06-01" @default.
- W2636639861 modified "2023-09-27" @default.
- W2636639861 title "P023 Investigating the clinical value of treponema pallidum PCR within a UK gum clinic" @default.
- W2636639861 doi "https://doi.org/10.1136/sextrans-2017-053232.69" @default.
- W2636639861 hasPublicationYear "2017" @default.
- W2636639861 type Work @default.
- W2636639861 sameAs 2636639861 @default.
- W2636639861 citedByCount "0" @default.
- W2636639861 crossrefType "journal-article" @default.
- W2636639861 hasAuthorship W2636639861A5023039237 @default.
- W2636639861 hasAuthorship W2636639861A5046091213 @default.
- W2636639861 hasAuthorship W2636639861A5079816611 @default.
- W2636639861 hasConcept C126322002 @default.
- W2636639861 hasConcept C141071460 @default.
- W2636639861 hasConcept C159654299 @default.
- W2636639861 hasConcept C16005928 @default.
- W2636639861 hasConcept C203014093 @default.
- W2636639861 hasConcept C2776908936 @default.
- W2636639861 hasConcept C2776983459 @default.
- W2636639861 hasConcept C2780187896 @default.
- W2636639861 hasConcept C2909760446 @default.
- W2636639861 hasConcept C2910147798 @default.
- W2636639861 hasConcept C3013748606 @default.
- W2636639861 hasConcept C3018810166 @default.
- W2636639861 hasConcept C45189115 @default.
- W2636639861 hasConcept C71924100 @default.
- W2636639861 hasConceptScore W2636639861C126322002 @default.
- W2636639861 hasConceptScore W2636639861C141071460 @default.
- W2636639861 hasConceptScore W2636639861C159654299 @default.
- W2636639861 hasConceptScore W2636639861C16005928 @default.
- W2636639861 hasConceptScore W2636639861C203014093 @default.
- W2636639861 hasConceptScore W2636639861C2776908936 @default.
- W2636639861 hasConceptScore W2636639861C2776983459 @default.
- W2636639861 hasConceptScore W2636639861C2780187896 @default.
- W2636639861 hasConceptScore W2636639861C2909760446 @default.
- W2636639861 hasConceptScore W2636639861C2910147798 @default.
- W2636639861 hasConceptScore W2636639861C3013748606 @default.
- W2636639861 hasConceptScore W2636639861C3018810166 @default.
- W2636639861 hasConceptScore W2636639861C45189115 @default.
- W2636639861 hasConceptScore W2636639861C71924100 @default.
- W2636639861 hasLocation W26366398611 @default.
- W2636639861 hasOpenAccess W2636639861 @default.
- W2636639861 hasPrimaryLocation W26366398611 @default.
- W2636639861 hasRelatedWork W2071216692 @default.
- W2636639861 hasRelatedWork W2090349421 @default.
- W2636639861 hasRelatedWork W2100438577 @default.
- W2636639861 hasRelatedWork W2116866431 @default.
- W2636639861 hasRelatedWork W2133883093 @default.
- W2636639861 hasRelatedWork W2155678643 @default.
- W2636639861 hasRelatedWork W2348475549 @default.
- W2636639861 hasRelatedWork W2352274466 @default.
- W2636639861 hasRelatedWork W2363342213 @default.
- W2636639861 hasRelatedWork W2366794891 @default.
- W2636639861 hasRelatedWork W2419277921 @default.
- W2636639861 hasRelatedWork W2756089982 @default.
- W2636639861 hasRelatedWork W2964294788 @default.
- W2636639861 hasRelatedWork W2972005380 @default.
- W2636639861 hasRelatedWork W3004218211 @default.
- W2636639861 hasRelatedWork W3023035317 @default.
- W2636639861 hasRelatedWork W3023536683 @default.
- W2636639861 hasRelatedWork W3139691094 @default.
- W2636639861 hasRelatedWork W3158209010 @default.
- W2636639861 hasRelatedWork W3208188818 @default.
- W2636639861 hasVolume "93" @default.
- W2636639861 isParatext "false" @default.
- W2636639861 isRetracted "false" @default.
- W2636639861 magId "2636639861" @default.
- W2636639861 workType "article" @default.