Matches in SemOpenAlex for { <https://semopenalex.org/work/W263733178> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W263733178 abstract "Although no definite risk factors have emerged for the different hematological malignancies, a viral cause has been postulated. Several studies have detected SV40 DNA sequences in tumor tissues obtained from non-Hodgkin's lymphoma patients. A link between SV40 and NHL is biologically plausible because SV40 causes hematological malignancies in laboratory rodents.We investigated 266 Egyptian cases of different hematological malignancies, for the presence of SV40 DNA using multiplex nested PCR technique. These cases consisted of 158 non-Hodgkin's lymphoma (NHL), 54 Hodgkin's disease(HD), 26 acute lymphocytic leukemia (ALL), 13 acute myeloid leukemia (AML), 8 chronic lymphoblastic leukemia (CLL), 7 chronic myeloid leukemia (CML), in addition to 34 subjects of control group.Our results have shown that SV40 DNA sequences were found in 53.8% of non-Hodgkin lymphoma patients, 29.6% of Hodgkin's disease patients, and 40.7% of different types of leukemia cases. Frequency of SV40 DNA sequences was higher in NHL patients compared to the other tumor cases. Also, frequency of SV40 DNA sequences was significantly higher (p<0.05) in NHL patients than in the control group. Regarding the different histological types of non-Hodgkin's lymphoma, SV40 DNA sequences were detected frequently in diffuse large B-cell lymphoma and in follicular lymphoma.The present study suggests that SV40 DNA virus is significantly associated with non-Hodgkin's lymphoma and might have a role in the development of these hematological malignancies. Polyomavirus SV40 may act as a cofactor in the pathogenesis of these tumors and this could lead to new diagnostic, therapeutic, and preventive approaches." @default.
- W263733178 created "2016-06-24" @default.
- W263733178 creator A5051202734 @default.
- W263733178 creator A5067415856 @default.
- W263733178 creator A5085912495 @default.
- W263733178 date "2007-01-01" @default.
- W263733178 modified "2023-09-24" @default.
- W263733178 title "Presence of simian virus 40 DNA sequences in egyptian patients with lymphoproliferative disorders." @default.
- W263733178 cites W1825790533 @default.
- W263733178 cites W1974825267 @default.
- W263733178 cites W1987160762 @default.
- W263733178 cites W2008955703 @default.
- W263733178 cites W2023418239 @default.
- W263733178 cites W2042068239 @default.
- W263733178 cites W2042532479 @default.
- W263733178 cites W2053604985 @default.
- W263733178 cites W2064074167 @default.
- W263733178 cites W2099056470 @default.
- W263733178 cites W2109277120 @default.
- W263733178 cites W2114772834 @default.
- W263733178 cites W2117754708 @default.
- W263733178 cites W2133383682 @default.
- W263733178 cites W2139945560 @default.
- W263733178 cites W2151917126 @default.
- W263733178 cites W2162779568 @default.
- W263733178 cites W2167327503 @default.
- W263733178 cites W2315498896 @default.
- W263733178 cites W2604938944 @default.
- W263733178 cites W569951484 @default.
- W263733178 cites W3146373184 @default.
- W263733178 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3068659" @default.
- W263733178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21475447" @default.
- W263733178 hasPublicationYear "2007" @default.
- W263733178 type Work @default.
- W263733178 sameAs 263733178 @default.
- W263733178 citedByCount "1" @default.
- W263733178 countsByYear W2637331782015 @default.
- W263733178 crossrefType "journal-article" @default.
- W263733178 hasAuthorship W263733178A5051202734 @default.
- W263733178 hasAuthorship W263733178A5067415856 @default.
- W263733178 hasAuthorship W263733178A5085912495 @default.
- W263733178 hasConcept C142724271 @default.
- W263733178 hasConcept C159047783 @default.
- W263733178 hasConcept C203014093 @default.
- W263733178 hasConcept C2522874641 @default.
- W263733178 hasConcept C2777938653 @default.
- W263733178 hasConcept C2778461978 @default.
- W263733178 hasConcept C2778729363 @default.
- W263733178 hasConcept C2779338263 @default.
- W263733178 hasConcept C502942594 @default.
- W263733178 hasConcept C71924100 @default.
- W263733178 hasConceptScore W263733178C142724271 @default.
- W263733178 hasConceptScore W263733178C159047783 @default.
- W263733178 hasConceptScore W263733178C203014093 @default.
- W263733178 hasConceptScore W263733178C2522874641 @default.
- W263733178 hasConceptScore W263733178C2777938653 @default.
- W263733178 hasConceptScore W263733178C2778461978 @default.
- W263733178 hasConceptScore W263733178C2778729363 @default.
- W263733178 hasConceptScore W263733178C2779338263 @default.
- W263733178 hasConceptScore W263733178C502942594 @default.
- W263733178 hasConceptScore W263733178C71924100 @default.
- W263733178 hasLocation W2637331781 @default.
- W263733178 hasOpenAccess W263733178 @default.
- W263733178 hasPrimaryLocation W2637331781 @default.
- W263733178 hasRelatedWork W1600032883 @default.
- W263733178 hasRelatedWork W1980713503 @default.
- W263733178 hasRelatedWork W1991096239 @default.
- W263733178 hasRelatedWork W1998911799 @default.
- W263733178 hasRelatedWork W2058660234 @default.
- W263733178 hasRelatedWork W2069778927 @default.
- W263733178 hasRelatedWork W2076631739 @default.
- W263733178 hasRelatedWork W2093101357 @default.
- W263733178 hasRelatedWork W2106105571 @default.
- W263733178 hasRelatedWork W2107093204 @default.
- W263733178 hasRelatedWork W2121079303 @default.
- W263733178 hasRelatedWork W2167624500 @default.
- W263733178 hasRelatedWork W2571255736 @default.
- W263733178 hasRelatedWork W2580995500 @default.
- W263733178 hasRelatedWork W2624949278 @default.
- W263733178 hasRelatedWork W2945948687 @default.
- W263733178 hasRelatedWork W2999503019 @default.
- W263733178 hasRelatedWork W3011066971 @default.
- W263733178 hasRelatedWork W3132609703 @default.
- W263733178 hasRelatedWork W72585919 @default.
- W263733178 isParatext "false" @default.
- W263733178 isRetracted "false" @default.
- W263733178 magId "263733178" @default.
- W263733178 workType "article" @default.