Matches in SemOpenAlex for { <https://semopenalex.org/work/W2638748052> ?p ?o ?g. }
- W2638748052 abstract "While exposure to nicotine during developmental periods can significantly affect brain development, studies examining the association between maternal smoking and autism spectrum disorder (ASD) in offspring have produced conflicting findings, and prior meta-analyses have found no significant association. Our meta-analysis used a novel approach of investigating population-level smoking metrics as moderators. The main meta-analysis, with 22 observational studies comprising 795,632 cases and 1,829,256 control participants, used a random-effects model to find no significant association between maternal smoking during pregnancy and ASD in offspring (pooled odds ratio (OR) = 1.16, 95% CI: 0.97-1.40). However, meta-regression analyses with moderators were significant when we matched pooled ORs with adult male smoking prevalence (z = 2.55, p = 0.01) in each country, using World Health Organization data. Our study shows that using population-level smoking metrics uncovers significant relationships between maternal smoking and ASD risk. Correlational analyses show that male smoking prevalence approximates secondhand smoke exposure. While we cannot exclude the possibility that our findings reflect the role of paternal or postnatal nicotine exposure, as opposed to maternal or in utero nicotine exposure, this study underlines the importance of investigating paternal and secondhand smoking in addition to maternal smoking in ASD." @default.
- W2638748052 created "2017-06-30" @default.
- W2638748052 creator A5020907559 @default.
- W2638748052 creator A5043892398 @default.
- W2638748052 creator A5067293178 @default.
- W2638748052 creator A5077026293 @default.
- W2638748052 date "2017-06-28" @default.
- W2638748052 modified "2023-10-14" @default.
- W2638748052 title "Maternal smoking and autism spectrum disorder: meta-analysis with population smoking metrics as moderators" @default.
- W2638748052 cites W1483729743 @default.
- W2638748052 cites W1487045871 @default.
- W2638748052 cites W1540845177 @default.
- W2638748052 cites W1759848617 @default.
- W2638748052 cites W1870927745 @default.
- W2638748052 cites W1924671000 @default.
- W2638748052 cites W1928951769 @default.
- W2638748052 cites W1932057135 @default.
- W2638748052 cites W1964435302 @default.
- W2638748052 cites W1968775421 @default.
- W2638748052 cites W1971038352 @default.
- W2638748052 cites W1981597830 @default.
- W2638748052 cites W1984559864 @default.
- W2638748052 cites W1989653808 @default.
- W2638748052 cites W1993168754 @default.
- W2638748052 cites W1993541380 @default.
- W2638748052 cites W1995105974 @default.
- W2638748052 cites W2000262719 @default.
- W2638748052 cites W2001275136 @default.
- W2638748052 cites W2016505872 @default.
- W2638748052 cites W2033021653 @default.
- W2638748052 cites W2036020905 @default.
- W2638748052 cites W2036216015 @default.
- W2638748052 cites W2036826698 @default.
- W2638748052 cites W2038903260 @default.
- W2638748052 cites W2045634296 @default.
- W2638748052 cites W2045845216 @default.
- W2638748052 cites W2058816380 @default.
- W2638748052 cites W2060968237 @default.
- W2638748052 cites W2066233893 @default.
- W2638748052 cites W2070031218 @default.
- W2638748052 cites W2070344083 @default.
- W2638748052 cites W2072987235 @default.
- W2638748052 cites W2074934756 @default.
- W2638748052 cites W2075495488 @default.
- W2638748052 cites W2087122753 @default.
- W2638748052 cites W2089128674 @default.
- W2638748052 cites W2091249025 @default.
- W2638748052 cites W2098092562 @default.
- W2638748052 cites W2099343145 @default.
- W2638748052 cites W2108450591 @default.
- W2638748052 cites W2111619439 @default.
- W2638748052 cites W2116475791 @default.
- W2638748052 cites W2120907497 @default.
- W2638748052 cites W2125435699 @default.
- W2638748052 cites W2126930838 @default.
- W2638748052 cites W2127973590 @default.
- W2638748052 cites W2129475546 @default.
- W2638748052 cites W2139168999 @default.
- W2638748052 cites W2140288760 @default.
- W2638748052 cites W2141384288 @default.
- W2638748052 cites W2142647774 @default.
- W2638748052 cites W2145847905 @default.
- W2638748052 cites W2149437480 @default.
- W2638748052 cites W2151382043 @default.
- W2638748052 cites W2153954987 @default.
- W2638748052 cites W2157823046 @default.
- W2638748052 cites W2169205464 @default.
- W2638748052 cites W2282418264 @default.
- W2638748052 cites W2303475965 @default.
- W2638748052 cites W2417118842 @default.
- W2638748052 cites W2591909999 @default.
- W2638748052 cites W4231637239 @default.
- W2638748052 cites W4246824881 @default.
- W2638748052 cites W4247665917 @default.
- W2638748052 cites W86769835 @default.
- W2638748052 doi "https://doi.org/10.1038/s41598-017-04413-1" @default.
- W2638748052 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5489536" @default.
- W2638748052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28659613" @default.
- W2638748052 hasPublicationYear "2017" @default.
- W2638748052 type Work @default.
- W2638748052 sameAs 2638748052 @default.
- W2638748052 citedByCount "43" @default.
- W2638748052 countsByYear W26387480522017 @default.
- W2638748052 countsByYear W26387480522018 @default.
- W2638748052 countsByYear W26387480522019 @default.
- W2638748052 countsByYear W26387480522020 @default.
- W2638748052 countsByYear W26387480522021 @default.
- W2638748052 countsByYear W26387480522022 @default.
- W2638748052 countsByYear W26387480522023 @default.
- W2638748052 crossrefType "journal-article" @default.
- W2638748052 hasAuthorship W2638748052A5020907559 @default.
- W2638748052 hasAuthorship W2638748052A5043892398 @default.
- W2638748052 hasAuthorship W2638748052A5067293178 @default.
- W2638748052 hasAuthorship W2638748052A5077026293 @default.
- W2638748052 hasBestOaLocation W26387480521 @default.
- W2638748052 hasConcept C112672928 @default.
- W2638748052 hasConcept C118552586 @default.
- W2638748052 hasConcept C126322002 @default.
- W2638748052 hasConcept C143095724 @default.
- W2638748052 hasConcept C144024400 @default.