Matches in SemOpenAlex for { <https://semopenalex.org/work/W2639844557> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2639844557 abstract "Newborn asphyxia is a complication during the perinatal period. The use of O2 for resuscitation has been broadly used in clinic. However, it has been demonstrated that oxygen overexposure induces oxidative stress (OS). We speculate that delaying postnatal in the extrauterine oxygenation status would preserve reducing equivalents, enhance redox adaptation, and protect oxyregulator tissues. The objective is evaluated OE status, induced by Fetal-Neonatal Transition (FNT) under different FiO2 conditions, in brain. FiO2 in pregnant mice was reduced from 21% to 14% or not the night before of delivery (G19). 8 hours after birth both group were led to room air (Hx14/21 and Nx21/21 groups) or hyperoxia (FiO2=100%) (Hx14/100 and Nx21/100 groups) and reset to 21% after 1 hour. The pups were sacrificed P1. We have determinated OS biomarkers (GSH/GSSG, Cysteine/ Cystine, Homocysteine/Homocystine), protein (m-tyr and o-tyr/Phe, 3NO2-tyr and 3Cl-tyr/tyr), and DNA (8OH-dG/2-dG) damage by HPLC-MS/MS and we have done a mitocondrial morphology study using ME. The results show a higher OS in the Nx21/100 group compared to the Hx14/100 group that decreases. The group Hx14/21 and Hx14/100 present a better mitochondrialcharacteristics compared to environmental conditions and their subsequent reoxygenation. Our results support that FNT under hypoxic conditions could be protective to face a possible event of newborn resuscitation." @default.
- W2639844557 created "2017-06-30" @default.
- W2639844557 creator A5036784121 @default.
- W2639844557 creator A5041501788 @default.
- W2639844557 creator A5065443829 @default.
- W2639844557 creator A5071955465 @default.
- W2639844557 creator A5074575313 @default.
- W2639844557 creator A5078795257 @default.
- W2639844557 date "2017-07-01" @default.
- W2639844557 modified "2023-09-28" @default.
- W2639844557 title "Cerebral protection during fetal-to-neonatal transition under hypoxic atmosphere" @default.
- W2639844557 doi "https://doi.org/10.1016/j.freeradbiomed.2017.04.327" @default.
- W2639844557 hasPublicationYear "2017" @default.
- W2639844557 type Work @default.
- W2639844557 sameAs 2639844557 @default.
- W2639844557 citedByCount "0" @default.
- W2639844557 crossrefType "journal-article" @default.
- W2639844557 hasAuthorship W2639844557A5036784121 @default.
- W2639844557 hasAuthorship W2639844557A5041501788 @default.
- W2639844557 hasAuthorship W2639844557A5065443829 @default.
- W2639844557 hasAuthorship W2639844557A5071955465 @default.
- W2639844557 hasAuthorship W2639844557A5074575313 @default.
- W2639844557 hasAuthorship W2639844557A5078795257 @default.
- W2639844557 hasConcept C126322002 @default.
- W2639844557 hasConcept C134018914 @default.
- W2639844557 hasConcept C16685009 @default.
- W2639844557 hasConcept C172680121 @default.
- W2639844557 hasConcept C178790620 @default.
- W2639844557 hasConcept C185592680 @default.
- W2639844557 hasConcept C2776151105 @default.
- W2639844557 hasConcept C2777714996 @default.
- W2639844557 hasConcept C2779234561 @default.
- W2639844557 hasConcept C2779914510 @default.
- W2639844557 hasConcept C2780672939 @default.
- W2639844557 hasConcept C42219234 @default.
- W2639844557 hasConcept C42407357 @default.
- W2639844557 hasConcept C540031477 @default.
- W2639844557 hasConcept C54355233 @default.
- W2639844557 hasConcept C71924100 @default.
- W2639844557 hasConcept C7836513 @default.
- W2639844557 hasConcept C86803240 @default.
- W2639844557 hasConceptScore W2639844557C126322002 @default.
- W2639844557 hasConceptScore W2639844557C134018914 @default.
- W2639844557 hasConceptScore W2639844557C16685009 @default.
- W2639844557 hasConceptScore W2639844557C172680121 @default.
- W2639844557 hasConceptScore W2639844557C178790620 @default.
- W2639844557 hasConceptScore W2639844557C185592680 @default.
- W2639844557 hasConceptScore W2639844557C2776151105 @default.
- W2639844557 hasConceptScore W2639844557C2777714996 @default.
- W2639844557 hasConceptScore W2639844557C2779234561 @default.
- W2639844557 hasConceptScore W2639844557C2779914510 @default.
- W2639844557 hasConceptScore W2639844557C2780672939 @default.
- W2639844557 hasConceptScore W2639844557C42219234 @default.
- W2639844557 hasConceptScore W2639844557C42407357 @default.
- W2639844557 hasConceptScore W2639844557C540031477 @default.
- W2639844557 hasConceptScore W2639844557C54355233 @default.
- W2639844557 hasConceptScore W2639844557C71924100 @default.
- W2639844557 hasConceptScore W2639844557C7836513 @default.
- W2639844557 hasConceptScore W2639844557C86803240 @default.
- W2639844557 hasLocation W26398445571 @default.
- W2639844557 hasOpenAccess W2639844557 @default.
- W2639844557 hasPrimaryLocation W26398445571 @default.
- W2639844557 hasRelatedWork W2022563717 @default.
- W2639844557 hasRelatedWork W2029500035 @default.
- W2639844557 hasRelatedWork W2031435299 @default.
- W2639844557 hasRelatedWork W2044605973 @default.
- W2639844557 hasRelatedWork W2057671007 @default.
- W2639844557 hasRelatedWork W2062871686 @default.
- W2639844557 hasRelatedWork W2067437653 @default.
- W2639844557 hasRelatedWork W2080355701 @default.
- W2639844557 hasRelatedWork W2104553977 @default.
- W2639844557 hasRelatedWork W2113256963 @default.
- W2639844557 hasRelatedWork W2188803823 @default.
- W2639844557 hasRelatedWork W2312636037 @default.
- W2639844557 hasRelatedWork W2469941740 @default.
- W2639844557 hasRelatedWork W2762284980 @default.
- W2639844557 hasRelatedWork W2804907344 @default.
- W2639844557 hasRelatedWork W2917828088 @default.
- W2639844557 hasRelatedWork W3029560405 @default.
- W2639844557 hasRelatedWork W3109201282 @default.
- W2639844557 hasRelatedWork W3152425883 @default.
- W2639844557 hasRelatedWork W437232011 @default.
- W2639844557 isParatext "false" @default.
- W2639844557 isRetracted "false" @default.
- W2639844557 magId "2639844557" @default.
- W2639844557 workType "article" @default.