FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2642565116> ?p ?o ?g. }

• W2642565116 endingPage "68" @default.
• W2642565116 startingPage "61" @default.
• W2642565116 abstract "Tripalmitoyl-S-glyceryl-l-Cys-Ser-(Lys)4 (Pam3CSK4) is a highly conserved molecular motif found in various classes of lipoproteins. The requirement for leukocyte to respond to synthetic Pam3CSK4 were studied. Pam3CSK4 primed neutrophils for a respiratory burst in a serum-dependent manner. Pam3CSK4 upregulated CD11b, CD14, and cytochrome b558, and downregulated Leu-8. Treatment of neutrophils with anti-CD14 antibodies and treatment of serum with anti-LPS binding protein (LBP) antibodies resulted in the inhibition of priming for respiratory burst by Pam3CSK4. It should be noted that LBP could not replicate the effects of serum in priming of neutrophils for respiratory burst by Pam3CSK4. Serum LBP bound to immobilized Pam3CSK4. Pam3CSK4 induced the interleukin-8 (IL-8) production by leukocytes in a serum-dependent manner. Further, Pam3CSK4-induced priming of neutrophils for respiratory burst was not inhibited by the LPS antagonists LA-14-PP, Rhodobacter sphaeroides LPS, or E5531, and Pam3CSK4-induced IL-8 production by leukocytes was not affected by LPS antagonist, E5531, indicating that Pam3CSK4 was recognized by a different receptor than LPS. Thus, Pam3CSK4 and LPS had similar biological activities and similar requirement to act on leukocytes, but were recognized by different receptors. Serum in the action of Pam3CSK4 on leukocytes was not replicated by LBP, suggesting that Pam3CSK4 might be disaggregated by serum to result in the activation of leukocytes." @default.
• W2642565116 created "2017-06-30" @default.
• W2642565116 creator A5001022589 @default.
• W2642565116 creator A5039640959 @default.
• W2642565116 creator A5046551862 @default.
• W2642565116 creator A5055748448 @default.
• W2642565116 creator A5070731703 @default.
• W2642565116 creator A5080351529 @default.
• W2642565116 creator A5085075310 @default.
• W2642565116 date "2017-09-01" @default.
• W2642565116 modified "2023-09-27" @default.
• W2642565116 title "Roles of serum in innate immune responses of human leukocytes to synthetic lipopeptide" @default.
• W2642565116 cites W1488995655 @default.
• W2642565116 cites W1498518287 @default.
• W2642565116 cites W1528996222 @default.
• W2642565116 cites W1565424988 @default.
• W2642565116 cites W1591029744 @default.
• W2642565116 cites W1867351039 @default.
• W2642565116 cites W1899417372 @default.
• W2642565116 cites W1944560965 @default.
• W2642565116 cites W1954062662 @default.
• W2642565116 cites W1957948512 @default.
• W2642565116 cites W1971824402 @default.
• W2642565116 cites W1976992284 @default.
• W2642565116 cites W1979381676 @default.
• W2642565116 cites W1989903543 @default.
• W2642565116 cites W1990022877 @default.
• W2642565116 cites W1997839876 @default.
• W2642565116 cites W2008077535 @default.
• W2642565116 cites W2041479446 @default.
• W2642565116 cites W2041933511 @default.
• W2642565116 cites W2052875305 @default.
• W2642565116 cites W2065172724 @default.
• W2642565116 cites W2090854355 @default.
• W2642565116 cites W2095799155 @default.
• W2642565116 cites W2107443644 @default.
• W2642565116 cites W2115328024 @default.
• W2642565116 cites W2115423440 @default.
• W2642565116 cites W2121279254 @default.
• W2642565116 cites W2138686669 @default.
• W2642565116 cites W2140776090 @default.
• W2642565116 cites W2142932698 @default.
• W2642565116 cites W2149999204 @default.
• W2642565116 cites W2163096565 @default.
• W2642565116 cites W2165027127 @default.
• W2642565116 cites W2170749809 @default.
• W2642565116 cites W2185732477 @default.
• W2642565116 cites W2404282373 @default.
• W2642565116 doi "https://doi.org/10.1016/j.intimp.2017.06.006" @default.
• W2642565116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28633072" @default.
• W2642565116 hasPublicationYear "2017" @default.
• W2642565116 type Work @default.
• W2642565116 sameAs 2642565116 @default.
• W2642565116 citedByCount "0" @default.
• W2642565116 crossrefType "journal-article" @default.
• W2642565116 hasAuthorship W2642565116A5001022589 @default.
• W2642565116 hasAuthorship W2642565116A5039640959 @default.
• W2642565116 hasAuthorship W2642565116A5046551862 @default.
• W2642565116 hasAuthorship W2642565116A5055748448 @default.
• W2642565116 hasAuthorship W2642565116A5070731703 @default.
• W2642565116 hasAuthorship W2642565116A5080351529 @default.
• W2642565116 hasAuthorship W2642565116A5085075310 @default.
• W2642565116 hasConcept C126322002 @default.
• W2642565116 hasConcept C136449434 @default.
• W2642565116 hasConcept C159654299 @default.
• W2642565116 hasConcept C170493617 @default.
• W2642565116 hasConcept C203014093 @default.
• W2642565116 hasConcept C2778513237 @default.
• W2642565116 hasConcept C2781236682 @default.
• W2642565116 hasConcept C71924100 @default.
• W2642565116 hasConcept C86803240 @default.
• W2642565116 hasConcept C98274493 @default.
• W2642565116 hasConcept C99971728 @default.
• W2642565116 hasConceptScore W2642565116C126322002 @default.
• W2642565116 hasConceptScore W2642565116C136449434 @default.
• W2642565116 hasConceptScore W2642565116C159654299 @default.
• W2642565116 hasConceptScore W2642565116C170493617 @default.
• W2642565116 hasConceptScore W2642565116C203014093 @default.
• W2642565116 hasConceptScore W2642565116C2778513237 @default.
• W2642565116 hasConceptScore W2642565116C2781236682 @default.
• W2642565116 hasConceptScore W2642565116C71924100 @default.
• W2642565116 hasConceptScore W2642565116C86803240 @default.
• W2642565116 hasConceptScore W2642565116C98274493 @default.
• W2642565116 hasConceptScore W2642565116C99971728 @default.
• W2642565116 hasLocation W26425651161 @default.
• W2642565116 hasLocation W26425651162 @default.
• W2642565116 hasOpenAccess W2642565116 @default.
• W2642565116 hasPrimaryLocation W26425651161 @default.
• W2642565116 hasRelatedWork W106286926 @default.
• W2642565116 hasRelatedWork W1914689199 @default.
• W2642565116 hasRelatedWork W1974055405 @default.
• W2642565116 hasRelatedWork W1977466146 @default.
• W2642565116 hasRelatedWork W1981462882 @default.
• W2642565116 hasRelatedWork W2028835724 @default.
• W2642565116 hasRelatedWork W2103675344 @default.
• W2642565116 hasRelatedWork W2178262593 @default.
• W2642565116 hasRelatedWork W2301839047 @default.
• W2642565116 hasRelatedWork W2902358729 @default.

• next