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• W264303945 abstract "Leishmaniasis is a disease that ranges in severity from skin lesions to serious disfigurement and fatal systemic infection. WHO estimates that the disease results in 2 million new cases a year, threatens 350 million people in 88 countries and that there are 12 million people currently infected worldwide. Current treatment is based on chemotherapy, which relies on a handful of drugs with serious limitations such as high cost, toxicity, difficult route of administration and lack of efficacy in endemic areas. Pentavalent antimonials have been the mainstay of antileishmanial therapy for over 70 years with second line drugs, Amphotericin B (AmB) and Pentamidine, used in case of antimonial failure. Since the introduction of miltefosine at the beginning of this century, no new antileishmanial compounds have been approved for human" @default.
• W264303945 created "2016-06-24" @default.
• W264303945 creator A5025984868 @default.
• W264303945 creator A5067623093 @default.
• W264303945 date "2009-01-01" @default.
• W264303945 modified "2023-09-23" @default.
• W264303945 title "Y SYSTEMS FOR THE TREATMENT AND PREVENTION OF LEISHMANIASIS TMENT AND PREVENTION OF LEISHMANIASIS TMENT AND PREVENTION OF LEISHMANIASIS TMENT AND PREVENTION OF LEISHMANIASIS TMENT AND PREVENTION OF LEISHMANIASIS" @default.
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• W264303945 hasPublicationYear "2009" @default.
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