Matches in SemOpenAlex for { <https://semopenalex.org/work/W2649014807> ?p ?o ?g. }
- W2649014807 endingPage "265" @default.
- W2649014807 startingPage "251" @default.
- W2649014807 abstract "Migraine is a common episodic neurological disorder with complex pathophysiology. It is generally recognized that: most migraine attacks start in the brain; migraine headache depends on the activation and sensitization of the trigeminovascular pain pathway; and cortical spreading depression (CSD) is the neurophysiological correlate of migraine aura. Most of the current molecular understanding of migraine comes from studies of familial hemiplegic migraine (FHM), a rare monogenic autosomal dominant form of migraine with aura (MA). This chapter focuses on the physiological role of the proteins encoded by the three known FHM genes and the functional consequences of FHM mutations. It also focuses on the insights into the mechanisms underlying susceptibility to CSD and initiation of migraine attacks obtained from the functional analysis of FHM mouse models. Three different FHM mouse models have been generated by introducing the human FHM1R192Q or S218L and FHM2W887R mutations into the orthologous genes." @default.
- W2649014807 created "2017-06-30" @default.
- W2649014807 creator A5006585668 @default.
- W2649014807 date "2017-06-19" @default.
- W2649014807 modified "2023-09-23" @default.
- W2649014807 title "Lessons from Familial Hemiplegic Migraine and Cortical Spreading Depression" @default.
- W2649014807 cites W1549058410 @default.
- W2649014807 cites W1564863670 @default.
- W2649014807 cites W1815876215 @default.
- W2649014807 cites W1841463848 @default.
- W2649014807 cites W1911059315 @default.
- W2649014807 cites W1920656927 @default.
- W2649014807 cites W1966049079 @default.
- W2649014807 cites W1972105123 @default.
- W2649014807 cites W1974474594 @default.
- W2649014807 cites W1976817332 @default.
- W2649014807 cites W1979009614 @default.
- W2649014807 cites W1980176764 @default.
- W2649014807 cites W1984440381 @default.
- W2649014807 cites W1986788837 @default.
- W2649014807 cites W1988594569 @default.
- W2649014807 cites W1991280665 @default.
- W2649014807 cites W1995839968 @default.
- W2649014807 cites W1998998851 @default.
- W2649014807 cites W2001216459 @default.
- W2649014807 cites W2010307662 @default.
- W2649014807 cites W2018241116 @default.
- W2649014807 cites W2025197615 @default.
- W2649014807 cites W2028131109 @default.
- W2649014807 cites W2032249449 @default.
- W2649014807 cites W2038049156 @default.
- W2649014807 cites W2038112426 @default.
- W2649014807 cites W2044444729 @default.
- W2649014807 cites W2046122045 @default.
- W2649014807 cites W2048713890 @default.
- W2649014807 cites W2053730818 @default.
- W2649014807 cites W2055448024 @default.
- W2649014807 cites W2056862640 @default.
- W2649014807 cites W2060914761 @default.
- W2649014807 cites W2063829584 @default.
- W2649014807 cites W2066080151 @default.
- W2649014807 cites W2066616580 @default.
- W2649014807 cites W2069107563 @default.
- W2649014807 cites W2070215711 @default.
- W2649014807 cites W2082047564 @default.
- W2649014807 cites W2085757176 @default.
- W2649014807 cites W2089897656 @default.
- W2649014807 cites W2095515981 @default.
- W2649014807 cites W2096181241 @default.
- W2649014807 cites W2101485524 @default.
- W2649014807 cites W2105423985 @default.
- W2649014807 cites W2107894529 @default.
- W2649014807 cites W2115817328 @default.
- W2649014807 cites W2118403409 @default.
- W2649014807 cites W2122708962 @default.
- W2649014807 cites W2130088345 @default.
- W2649014807 cites W2133566590 @default.
- W2649014807 cites W2134784646 @default.
- W2649014807 cites W2135870029 @default.
- W2649014807 cites W2136385694 @default.
- W2649014807 cites W2144759791 @default.
- W2649014807 cites W2152830480 @default.
- W2649014807 cites W2153117162 @default.
- W2649014807 cites W2154887381 @default.
- W2649014807 cites W2156503648 @default.
- W2649014807 cites W2165421338 @default.
- W2649014807 cites W2312098387 @default.
- W2649014807 cites W2334303491 @default.
- W2649014807 cites W4298360357 @default.
- W2649014807 cites W46438429 @default.
- W2649014807 doi "https://doi.org/10.1002/9781118967225.ch15" @default.
- W2649014807 hasPublicationYear "2017" @default.
- W2649014807 type Work @default.
- W2649014807 sameAs 2649014807 @default.
- W2649014807 citedByCount "2" @default.
- W2649014807 countsByYear W26490148072018 @default.
- W2649014807 countsByYear W26490148072020 @default.
- W2649014807 crossrefType "other" @default.
- W2649014807 hasAuthorship W2649014807A5006585668 @default.
- W2649014807 hasConcept C118552586 @default.
- W2649014807 hasConcept C122356138 @default.
- W2649014807 hasConcept C139719470 @default.
- W2649014807 hasConcept C152478114 @default.
- W2649014807 hasConcept C15744967 @default.
- W2649014807 hasConcept C162324750 @default.
- W2649014807 hasConcept C169760540 @default.
- W2649014807 hasConcept C2776497919 @default.
- W2649014807 hasConcept C2776867660 @default.
- W2649014807 hasConcept C2777350023 @default.
- W2649014807 hasConcept C2778042195 @default.
- W2649014807 hasConcept C2778541695 @default.
- W2649014807 hasConcept C71924100 @default.
- W2649014807 hasConceptScore W2649014807C118552586 @default.
- W2649014807 hasConceptScore W2649014807C122356138 @default.
- W2649014807 hasConceptScore W2649014807C139719470 @default.
- W2649014807 hasConceptScore W2649014807C152478114 @default.
- W2649014807 hasConceptScore W2649014807C15744967 @default.
- W2649014807 hasConceptScore W2649014807C162324750 @default.