Matches in SemOpenAlex for { <https://semopenalex.org/work/W26606713> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W26606713 abstract "ABSTRACT The stimulatory effect of endotoxins on hematopoiesis is well established. We were interested in the question whether this is a direct effect of endotoxin or whether this is due to histamine or serotonin substances which are released following endotoxin injection. We determined splenic and femoral CFUs and CFUc after injection with histamine in mice. Serum CSF levels were followed after histamine and serotonin injection. The results indicated that histamine had no effect on CFUs and CFUc in vivo similar to that of endotoxin. Both, histamine and serotonin failed to induce elevation in CSF serum levels. We were interested also in the effect of a methylated preparation extracted according to the method of Nowotny (1963) from S. marcescens endotoxin which has reduced toxicity. We found that this preparation induces within 24 h a nonspecific tolerance against lethal doses of endotoxin and lethal X-irradiation. This substance stimulates hematopoiesis, particularly granulopoiesis, as demonstrated by kinetic studies of blood, splenic and femoral CFUs and CFUc, peripheral differential blood counts and serum CSF levels. These results suggest that this substance increases nonspecific resistance due to its capacity to stimulate granulopoiesis. In the state of nonspecific tolerance CSF levels increased to the same extent as in nontolerant animals. In tolerant mice no inhibitors of CSF activity were found in undiluted serum." @default.
- W26606713 created "2016-06-24" @default.
- W26606713 creator A5046452074 @default.
- W26606713 creator A5085407899 @default.
- W26606713 date "1980-01-01" @default.
- W26606713 modified "2023-09-26" @default.
- W26606713 title "THE EFFECT OF ENDOTOXIC SUBSTANCES ON GRANULOPOIESIS" @default.
- W26606713 cites W1514308937 @default.
- W26606713 cites W1995603494 @default.
- W26606713 cites W2002287505 @default.
- W26606713 cites W2016195250 @default.
- W26606713 cites W2021373636 @default.
- W26606713 cites W2027669728 @default.
- W26606713 cites W2048104971 @default.
- W26606713 cites W2048416207 @default.
- W26606713 cites W2052877271 @default.
- W26606713 cites W2053576571 @default.
- W26606713 cites W2088303899 @default.
- W26606713 cites W2103546044 @default.
- W26606713 cites W2150554044 @default.
- W26606713 cites W2168607251 @default.
- W26606713 cites W2197611523 @default.
- W26606713 cites W2250534797 @default.
- W26606713 cites W2293213886 @default.
- W26606713 cites W2299275321 @default.
- W26606713 cites W2321990599 @default.
- W26606713 cites W2335660413 @default.
- W26606713 cites W2395270972 @default.
- W26606713 cites W2407407933 @default.
- W26606713 cites W2415316184 @default.
- W26606713 doi "https://doi.org/10.1016/b978-0-08-024952-0.50040-5" @default.
- W26606713 hasPublicationYear "1980" @default.
- W26606713 type Work @default.
- W26606713 sameAs 26606713 @default.
- W26606713 citedByCount "2" @default.
- W26606713 crossrefType "book-chapter" @default.
- W26606713 hasAuthorship W26606713A5046452074 @default.
- W26606713 hasAuthorship W26606713A5085407899 @default.
- W26606713 hasConcept C109159458 @default.
- W26606713 hasConcept C1122143 @default.
- W26606713 hasConcept C126322002 @default.
- W26606713 hasConcept C134018914 @default.
- W26606713 hasConcept C150903083 @default.
- W26606713 hasConcept C170493617 @default.
- W26606713 hasConcept C185592680 @default.
- W26606713 hasConcept C207001950 @default.
- W26606713 hasConcept C2775864247 @default.
- W26606713 hasConcept C2779452902 @default.
- W26606713 hasConcept C28328180 @default.
- W26606713 hasConcept C3019921246 @default.
- W26606713 hasConcept C54355233 @default.
- W26606713 hasConcept C71924100 @default.
- W26606713 hasConcept C86803240 @default.
- W26606713 hasConcept C98274493 @default.
- W26606713 hasConceptScore W26606713C109159458 @default.
- W26606713 hasConceptScore W26606713C1122143 @default.
- W26606713 hasConceptScore W26606713C126322002 @default.
- W26606713 hasConceptScore W26606713C134018914 @default.
- W26606713 hasConceptScore W26606713C150903083 @default.
- W26606713 hasConceptScore W26606713C170493617 @default.
- W26606713 hasConceptScore W26606713C185592680 @default.
- W26606713 hasConceptScore W26606713C207001950 @default.
- W26606713 hasConceptScore W26606713C2775864247 @default.
- W26606713 hasConceptScore W26606713C2779452902 @default.
- W26606713 hasConceptScore W26606713C28328180 @default.
- W26606713 hasConceptScore W26606713C3019921246 @default.
- W26606713 hasConceptScore W26606713C54355233 @default.
- W26606713 hasConceptScore W26606713C71924100 @default.
- W26606713 hasConceptScore W26606713C86803240 @default.
- W26606713 hasConceptScore W26606713C98274493 @default.
- W26606713 hasLocation W266067131 @default.
- W26606713 hasOpenAccess W26606713 @default.
- W26606713 hasPrimaryLocation W266067131 @default.
- W26606713 hasRelatedWork W1904114400 @default.
- W26606713 hasRelatedWork W2037309740 @default.
- W26606713 hasRelatedWork W2041274971 @default.
- W26606713 hasRelatedWork W2051427831 @default.
- W26606713 hasRelatedWork W2090008530 @default.
- W26606713 hasRelatedWork W2110531696 @default.
- W26606713 hasRelatedWork W2122339994 @default.
- W26606713 hasRelatedWork W2145343991 @default.
- W26606713 hasRelatedWork W2188779126 @default.
- W26606713 hasRelatedWork W2296837386 @default.
- W26606713 hasRelatedWork W2315027181 @default.
- W26606713 hasRelatedWork W2322255705 @default.
- W26606713 hasRelatedWork W2331200156 @default.
- W26606713 hasRelatedWork W2386445338 @default.
- W26606713 hasRelatedWork W2400234063 @default.
- W26606713 hasRelatedWork W2417620370 @default.
- W26606713 hasRelatedWork W2418749096 @default.
- W26606713 hasRelatedWork W2597795792 @default.
- W26606713 hasRelatedWork W3142523606 @default.
- W26606713 hasRelatedWork W19068345 @default.
- W26606713 isParatext "false" @default.
- W26606713 isRetracted "false" @default.
- W26606713 magId "26606713" @default.
- W26606713 workType "book-chapter" @default.