FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2663374310> ?p ?o ?g. }

• W2663374310 abstract "One of the fundamental issues in the microbiome research is characterization of the healthy human microbiota. Recent studies have elucidated substantial divergences in the microbiome structure between healthy individuals from different race and ethnicity. This review provides a comprehensive account of such geography, ethnicity or life-style-specific variations in healthy microbiome at five major body habitats – Gut, Oral-cavity, Respiratory Tract, Skin and Urogenital Tract (UGT). The review focuses on the general trend in the human microbiome evolution - a gradual transition in the gross compositional structure along with a continual decrease in diversity of the microbiome, especially of the gut microbiome, as the human populations passed through three stages of subsistence like foraging, rural farming and industrialized urban western life. In general, gut microbiome of the hunter-gatherer populations is highly abundant with Prevotella, Proteobacteria, Spirochaetes, Clostridiales, Ruminobacter etc., while those of the urban communities are often enriched in Bacteroides, Bifidobacterium and Firmicutes. The oral and skin microbiome are the next most diverse among different populations, while respiratory tract and UGT microbiome show lesser variations. Higher microbiome diversity is observed for oral-cavity in hunter-gatherer group with higher prevalence of Haemophilus than agricultural group. In case of skin microbiome, rural and urban Chinese populations show variation in abundance of Trabulsiella and Propionibacterium. On the basis of published data, we have characterized the core microbiota – the set of genera commonly found in all populations, irrespective of their geographic locations, ethnicity or mode of subsistence. We have also identified the major factors responsible for geography-based alterations in microbiota; though it is not yet clear which factor plays a dominant role in shaping the microbiome – nature or nurture, host genetics or his environment. Some of the geographical/racial variations in microbiome structure have been attributed to differences in host genetics and innate/adaptive immunity, while in many other cases, cultural/behavioral features like diet, hygiene, parasitic load, environmental exposure etc. overshadow genetics. The ethnicity or population-specific variations in human microbiome composition, as reviewed in this report, question the universality of the microbiome-based therapeutic strategies and recommend for geographically tailored community-scale approaches to microbiome engineering." @default.
• W2663374310 created "2017-06-30" @default.
• W2663374310 creator A5006621565 @default.
• W2663374310 creator A5027104469 @default.
• W2663374310 creator A5049123297 @default.
• W2663374310 date "2017-06-23" @default.
• W2663374310 modified "2023-10-14" @default.
• W2663374310 title "Geography, Ethnicity or Subsistence-Specific Variations in Human Microbiome Composition and Diversity" @default.
• W2663374310 cites W1125694555 @default.
• W2663374310 cites W126193691 @default.
• W2663374310 cites W1521289157 @default.
• W2663374310 cites W1527957830 @default.
• W2663374310 cites W1568043102 @default.
• W2663374310 cites W1588999779 @default.
• W2663374310 cites W1655950349 @default.
• W2663374310 cites W1679625911 @default.
• W2663374310 cites W1809188985 @default.
• W2663374310 cites W1934662080 @default.
• W2663374310 cites W1948774627 @default.
• W2663374310 cites W1967453563 @default.
• W2663374310 cites W1968813912 @default.
• W2663374310 cites W1971415551 @default.
• W2663374310 cites W1972528270 @default.
• W2663374310 cites W1972683406 @default.
• W2663374310 cites W1974577714 @default.
• W2663374310 cites W1978260581 @default.
• W2663374310 cites W1978709058 @default.
• W2663374310 cites W1980725116 @default.
• W2663374310 cites W1983699011 @default.
• W2663374310 cites W1986572572 @default.
• W2663374310 cites W1988809566 @default.
• W2663374310 cites W1989496014 @default.
• W2663374310 cites W1994668628 @default.
• W2663374310 cites W1998490921 @default.
• W2663374310 cites W2009912469 @default.
• W2663374310 cites W2012289680 @default.
• W2663374310 cites W2013371150 @default.
• W2663374310 cites W2014766007 @default.
• W2663374310 cites W2020913417 @default.
• W2663374310 cites W2023615726 @default.
• W2663374310 cites W2024330772 @default.
• W2663374310 cites W2025537667 @default.
• W2663374310 cites W2030531562 @default.
• W2663374310 cites W2030928347 @default.
• W2663374310 cites W2032230795 @default.
• W2663374310 cites W2033829415 @default.
• W2663374310 cites W2034883472 @default.
• W2663374310 cites W2034985438 @default.
• W2663374310 cites W2037701117 @default.
• W2663374310 cites W2042295984 @default.
• W2663374310 cites W2046454404 @default.
• W2663374310 cites W2047885502 @default.
• W2663374310 cites W2052797817 @default.
• W2663374310 cites W2055107205 @default.
• W2663374310 cites W2056782822 @default.
• W2663374310 cites W2058710717 @default.
• W2663374310 cites W2062952734 @default.
• W2663374310 cites W2063890406 @default.
• W2663374310 cites W2065738801 @default.
• W2663374310 cites W2071841602 @default.
• W2663374310 cites W2074225908 @default.
• W2663374310 cites W2080554049 @default.
• W2663374310 cites W2084070275 @default.
• W2663374310 cites W2085423479 @default.
• W2663374310 cites W2087278385 @default.
• W2663374310 cites W2087292184 @default.
• W2663374310 cites W2094036101 @default.
• W2663374310 cites W2098297902 @default.
• W2663374310 cites W2104468194 @default.
• W2663374310 cites W2105570709 @default.
• W2663374310 cites W2106355313 @default.
• W2663374310 cites W2107097628 @default.
• W2663374310 cites W2111304349 @default.
• W2663374310 cites W2113925621 @default.
• W2663374310 cites W2115944543 @default.
• W2663374310 cites W2120822922 @default.
• W2663374310 cites W2121580723 @default.
• W2663374310 cites W2121748291 @default.
• W2663374310 cites W2124771292 @default.
• W2663374310 cites W2125826054 @default.
• W2663374310 cites W2128218039 @default.
• W2663374310 cites W2128769815 @default.
• W2663374310 cites W2130725058 @default.
• W2663374310 cites W2131186249 @default.
• W2663374310 cites W2137090067 @default.
• W2663374310 cites W2138061716 @default.
• W2663374310 cites W2140679462 @default.
• W2663374310 cites W2141980700 @default.
• W2663374310 cites W2143248248 @default.
• W2663374310 cites W2144494558 @default.
• W2663374310 cites W2145720531 @default.
• W2663374310 cites W2148406307 @default.
• W2663374310 cites W2158902491 @default.
• W2663374310 cites W2159497758 @default.
• W2663374310 cites W2160464661 @default.
• W2663374310 cites W2161899152 @default.
• W2663374310 cites W2162088497 @default.
• W2663374310 cites W2166358290 @default.
• W2663374310 cites W2167016577 @default.
• W2663374310 cites W2167062509 @default.

• next