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- W2663610293 abstract "ABSTRACT Proteins of the Wiskott–Aldrich syndrome protein (WASP) family function as nucleation-promoting factors for the ubiquitously expressed Arp2/3 complex, which drives the generation of branched actin filaments. Arp2/3-generated actin regulates diverse cellular processes, including the formation of lamellipodia and filopodia, endocytosis and/or phagocytosis at the plasma membrane, and the generation of cargo-laden vesicles from organelles including the Golgi, endoplasmic reticulum (ER) and the endo-lysosomal network. Recent studies have also identified roles for WASP family members in promoting actin dynamics at the centrosome, influencing nuclear shape and membrane remodeling events leading to the generation of autophagosomes. Interestingly, several WASP family members have also been observed in the nucleus where they directly influence gene expression by serving as molecular platforms for the assembly of epigenetic and transcriptional machinery. In this Cell Science at a Glance article and accompanying poster, we provide an update on the subcellular roles of WHAMM, JMY and WASH (also known as WASHC1), as well as their mechanisms of regulation and emerging functions within the cell." @default.
- W2663610293 created "2017-06-30" @default.
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- W2663610293 date "2017-01-01" @default.
- W2663610293 modified "2023-10-16" @default.
- W2663610293 title "Cellular functions of WASP family proteins at a glance" @default.
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- W2663610293 cites W1530007708 @default.
- W2663610293 cites W1629840740 @default.
- W2663610293 cites W1761476131 @default.
- W2663610293 cites W1779577685 @default.
- W2663610293 cites W1843647340 @default.
- W2663610293 cites W1856497061 @default.
- W2663610293 cites W1907132844 @default.
- W2663610293 cites W1965471102 @default.
- W2663610293 cites W1967248496 @default.
- W2663610293 cites W1967904525 @default.
- W2663610293 cites W1968153823 @default.
- W2663610293 cites W1970290685 @default.
- W2663610293 cites W1973911766 @default.
- W2663610293 cites W1982307380 @default.
- W2663610293 cites W1982323979 @default.
- W2663610293 cites W1982863538 @default.
- W2663610293 cites W1983044117 @default.
- W2663610293 cites W1983374348 @default.
- W2663610293 cites W1984259502 @default.
- W2663610293 cites W1991549216 @default.
- W2663610293 cites W1991752238 @default.
- W2663610293 cites W1993201929 @default.
- W2663610293 cites W1996747646 @default.
- W2663610293 cites W1999708992 @default.
- W2663610293 cites W2007516779 @default.
- W2663610293 cites W2010847653 @default.
- W2663610293 cites W2013700992 @default.
- W2663610293 cites W2023583582 @default.
- W2663610293 cites W2027938923 @default.
- W2663610293 cites W2030369847 @default.
- W2663610293 cites W2031730524 @default.
- W2663610293 cites W2032793177 @default.
- W2663610293 cites W2035447681 @default.
- W2663610293 cites W2037936544 @default.
- W2663610293 cites W2038909340 @default.
- W2663610293 cites W2039985150 @default.
- W2663610293 cites W2042884520 @default.
- W2663610293 cites W2043168782 @default.
- W2663610293 cites W2044621729 @default.
- W2663610293 cites W2052456480 @default.
- W2663610293 cites W2059161447 @default.
- W2663610293 cites W2060628544 @default.
- W2663610293 cites W2061076810 @default.
- W2663610293 cites W2063130661 @default.
- W2663610293 cites W2063690790 @default.
- W2663610293 cites W2065619900 @default.
- W2663610293 cites W2066953183 @default.
- W2663610293 cites W2067078346 @default.
- W2663610293 cites W2079385284 @default.
- W2663610293 cites W2081228019 @default.
- W2663610293 cites W2089472706 @default.
- W2663610293 cites W2092327237 @default.
- W2663610293 cites W2094539919 @default.
- W2663610293 cites W2099472310 @default.
- W2663610293 cites W2103428229 @default.
- W2663610293 cites W2104095808 @default.
- W2663610293 cites W2104909766 @default.
- W2663610293 cites W2113249117 @default.
- W2663610293 cites W2115987666 @default.
- W2663610293 cites W2120377818 @default.
- W2663610293 cites W2121889667 @default.
- W2663610293 cites W2124241990 @default.
- W2663610293 cites W2129580137 @default.
- W2663610293 cites W2133679611 @default.
- W2663610293 cites W2139094884 @default.
- W2663610293 cites W2143461921 @default.
- W2663610293 cites W2154637838 @default.
- W2663610293 cites W2157096314 @default.
- W2663610293 cites W2161159517 @default.
- W2663610293 cites W2211562053 @default.
- W2663610293 cites W2270848082 @default.
- W2663610293 cites W2286227686 @default.
- W2663610293 cites W2311815664 @default.
- W2663610293 cites W2316238346 @default.
- W2663610293 cites W2345206408 @default.
- W2663610293 cites W2469926161 @default.
- W2663610293 cites W2523259950 @default.
- W2663610293 cites W2552966922 @default.
- W2663610293 cites W2598302417 @default.
- W2663610293 cites W2605245547 @default.
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- W2663610293 doi "https://doi.org/10.1242/jcs.199570" @default.
- W2663610293 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5536917" @default.
- W2663610293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28646090" @default.
- W2663610293 hasPublicationYear "2017" @default.
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