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- W2667766843 abstract "ABSTRACT We studied multiple sclerosis (MS) patients with the HLA-DQB1*06:02 allele and compared them with MS patients who did not carry the HLA-DQB1*06:02 allele. We analyzed clinical and neurophysiological criteria for narcolepsy in six MS patients with HLA-DQB1*06:02, compared with 12 MS patients who were HLA-DQB1*06:02 non-carriers. Only two patients with HLA-DQB1*06:02 allele scored higher than 10 on the Epworth Sleepiness Scale. Polysomnography recording parameters and the multiple sleep latency test showed an absence of narcolepsy in the study group. Our study suggested no significant correlation between narcolepsy, MS and HLA-DQB1*06:02. The HLA-DQB1*06:02 allele alone was not sufficient to cause MS patients to develop narcolepsy." @default.
- W2667766843 created "2017-06-30" @default.
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- W2667766843 date "2017-06-01" @default.
- W2667766843 modified "2023-10-17" @default.
- W2667766843 title "Is there a relationship between narcolepsy, multiple sclerosis and HLA-DQB1*06:02?" @default.
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- W2667766843 doi "https://doi.org/10.1590/0004-282x20170063" @default.
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