FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2681330807> ?p ?o ?g. }

• W2681330807 endingPage "2053" @default.
• W2681330807 startingPage "2038" @default.
• W2681330807 abstract "Plants depend on innate immunity to prevent disease. Plant pathogenic bacteria, like Pseudomonas syringae and Xanthomonas campestris, use the type III secretion system as a molecular syringe to inject type III secreted effector (T3SE) proteins in plants. The primary function of most T3SEs is to suppress immunity; however, the plant can evolve nucleotide-binding domain-leucine-rich repeat domain-containing proteins to recognize specific T3SEs. The AtZAR1 NLR induces strong defense responses against P. syringae and X. campestris. The P. syringae T3SE HopZ1a is an acetyltransferase that acetylates the pseudokinase AtZED1 and triggers recognition by AtZAR1. However, little is known about the molecular mechanisms that lead to AtZAR1-induced immunity in response to HopZ1a. We established a transient expression system in Nicotiana benthamiana to study detailed interactions among HopZ1a, AtZED1, and AtZAR1. We show that the AtZAR1 immune pathway is conserved in N. benthamiana and identify AtZAR1 domains, and residues in AtZAR1 and AtZED1, that are important for immunity and protein-protein interactions in planta and in yeast (Saccharomyces cerevisiae). We show that the coiled-coil domain of AtZAR1 oligomerizes, and this domain acts as a signal to induce immunity. This detailed analysis of the AtZAR1-AtZED1 protein complex provides a better understanding of the immune signaling hub controlled by AtZAR1." @default.
• W2681330807 created "2017-06-30" @default.
• W2681330807 creator A5000674264 @default.
• W2681330807 creator A5023045825 @default.
• W2681330807 creator A5041730785 @default.
• W2681330807 creator A5042714354 @default.
• W2681330807 date "2017-06-26" @default.
• W2681330807 modified "2023-10-17" @default.
• W2681330807 title "Analysis of the ZAR1 Immune Complex Reveals Determinants for Immunity and Molecular Interactions" @default.
• W2681330807 cites W112520524 @default.
• W2681330807 cites W1542452066 @default.
• W2681330807 cites W1626508217 @default.
• W2681330807 cites W1803102843 @default.
• W2681330807 cites W1929044522 @default.
• W2681330807 cites W1963837218 @default.
• W2681330807 cites W1973328229 @default.
• W2681330807 cites W1975293482 @default.
• W2681330807 cites W1977354015 @default.
• W2681330807 cites W1979979849 @default.
• W2681330807 cites W1981932072 @default.
• W2681330807 cites W1985835804 @default.
• W2681330807 cites W1993339029 @default.
• W2681330807 cites W1993946088 @default.
• W2681330807 cites W2004507419 @default.
• W2681330807 cites W2005180190 @default.
• W2681330807 cites W2016737807 @default.
• W2681330807 cites W2018806611 @default.
• W2681330807 cites W2021071631 @default.
• W2681330807 cites W2026405777 @default.
• W2681330807 cites W2043298705 @default.
• W2681330807 cites W2045940487 @default.
• W2681330807 cites W2049579557 @default.
• W2681330807 cites W2050870561 @default.
• W2681330807 cites W2052504838 @default.
• W2681330807 cites W2054275665 @default.
• W2681330807 cites W2059856607 @default.
• W2681330807 cites W2064138871 @default.
• W2681330807 cites W2068335977 @default.
• W2681330807 cites W2070113749 @default.
• W2681330807 cites W2075962299 @default.
• W2681330807 cites W2076479752 @default.
• W2681330807 cites W2076650069 @default.
• W2681330807 cites W2082026887 @default.
• W2681330807 cites W2087675271 @default.
• W2681330807 cites W2090723161 @default.
• W2681330807 cites W2090881705 @default.
• W2681330807 cites W2093684370 @default.
• W2681330807 cites W2097429168 @default.
• W2681330807 cites W2102564339 @default.
• W2681330807 cites W2105850758 @default.
• W2681330807 cites W2106424272 @default.
• W2681330807 cites W2108582238 @default.
• W2681330807 cites W2113311439 @default.
• W2681330807 cites W2115804728 @default.
• W2681330807 cites W2116122104 @default.
• W2681330807 cites W2116160740 @default.
• W2681330807 cites W2120698877 @default.
• W2681330807 cites W2122245399 @default.
• W2681330807 cites W2123679376 @default.
• W2681330807 cites W2124439705 @default.
• W2681330807 cites W2124600207 @default.
• W2681330807 cites W2126598492 @default.
• W2681330807 cites W2126799350 @default.
• W2681330807 cites W2127109439 @default.
• W2681330807 cites W2129997424 @default.
• W2681330807 cites W2130330131 @default.
• W2681330807 cites W2135002888 @default.
• W2681330807 cites W2137248850 @default.
• W2681330807 cites W2138472234 @default.
• W2681330807 cites W2138946332 @default.
• W2681330807 cites W2140177375 @default.
• W2681330807 cites W2141636493 @default.
• W2681330807 cites W2142414495 @default.
• W2681330807 cites W2149118179 @default.
• W2681330807 cites W2150069840 @default.
• W2681330807 cites W2153544371 @default.
• W2681330807 cites W2160155425 @default.
• W2681330807 cites W2160701551 @default.
• W2681330807 cites W2161343058 @default.
• W2681330807 cites W2162515800 @default.
• W2681330807 cites W2162800927 @default.
• W2681330807 cites W2164461702 @default.
• W2681330807 cites W2168154884 @default.
• W2681330807 cites W2180617533 @default.
• W2681330807 cites W2223338073 @default.
• W2681330807 cites W2344452957 @default.
• W2681330807 cites W2345591463 @default.
• W2681330807 cites W2399410002 @default.
• W2681330807 cites W2482775732 @default.
• W2681330807 cites W2516695993 @default.
• W2681330807 cites W2538109207 @default.
• W2681330807 cites W2545827800 @default.
• W2681330807 cites W2558438718 @default.
• W2681330807 cites W2595254339 @default.
• W2681330807 cites W2622162736 @default.
• W2681330807 doi "https://doi.org/10.1104/pp.17.00441" @default.
• W2681330807 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5543953" @default.
• W2681330807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28652264" @default.

• next