Matches in SemOpenAlex for { <https://semopenalex.org/work/W2682783302> ?p ?o ?g. }
- W2682783302 endingPage "7476" @default.
- W2682783302 startingPage "7470" @default.
- W2682783302 abstract "N-glycosylation plays an important role in chief biological and pathological processes. Quantifying the N-glycan is important since glycan alterations are related to many diseases. In this study, we developed a novel N-glycan quantitation approach using metallic element chelated tag labeling (MeCTL) through reductive amination. The MeCTL strategy is of high labeling efficiency and accurate in quantitation with high reproducibility (CV < 17.03%) and good linearity (R2 > 0.99) within 2 orders of magnitude of dynamic range. Additionally, it provides significant cross-ring fragmentation to distinguish N-glycan isomers. Furthermore, multiplex quantitation by chelation with several different rare earth elements can be achieved. At last, this strategy has been successfully used for evaluation of N-glycan changes in human serum associated with CRC, indicating its potential in clinical applications including disease N-glycome profiling and relative quantitation." @default.
- W2682783302 created "2017-06-30" @default.
- W2682783302 creator A5022889126 @default.
- W2682783302 creator A5042973046 @default.
- W2682783302 creator A5045389279 @default.
- W2682783302 creator A5052077609 @default.
- W2682783302 creator A5052342599 @default.
- W2682783302 creator A5063499064 @default.
- W2682783302 creator A5072580346 @default.
- W2682783302 date "2017-07-07" @default.
- W2682783302 modified "2023-10-15" @default.
- W2682783302 title "Metallic Element Chelated Tag Labeling (MeCTL) for Quantitation of N-Glycans in MALDI-MS" @default.
- W2682783302 cites W1129453464 @default.
- W2682783302 cites W1182461782 @default.
- W2682783302 cites W1599717092 @default.
- W2682783302 cites W1971912787 @default.
- W2682783302 cites W1981989535 @default.
- W2682783302 cites W1982349431 @default.
- W2682783302 cites W1991389286 @default.
- W2682783302 cites W1994956298 @default.
- W2682783302 cites W1996310146 @default.
- W2682783302 cites W2000671183 @default.
- W2682783302 cites W2001634746 @default.
- W2682783302 cites W2002334423 @default.
- W2682783302 cites W2014847406 @default.
- W2682783302 cites W2021455850 @default.
- W2682783302 cites W2021608772 @default.
- W2682783302 cites W2024191468 @default.
- W2682783302 cites W2030068202 @default.
- W2682783302 cites W2048511322 @default.
- W2682783302 cites W2056145324 @default.
- W2682783302 cites W2068339549 @default.
- W2682783302 cites W2079092974 @default.
- W2682783302 cites W2079168158 @default.
- W2682783302 cites W2085700392 @default.
- W2682783302 cites W2097801051 @default.
- W2682783302 cites W2101657558 @default.
- W2682783302 cites W2102750797 @default.
- W2682783302 cites W2104860744 @default.
- W2682783302 cites W2114860944 @default.
- W2682783302 cites W2185622602 @default.
- W2682783302 cites W2236878792 @default.
- W2682783302 cites W2312304310 @default.
- W2682783302 cites W2318126049 @default.
- W2682783302 cites W2320830275 @default.
- W2682783302 cites W2473927860 @default.
- W2682783302 cites W2523343093 @default.
- W2682783302 cites W304117529 @default.
- W2682783302 doi "https://doi.org/10.1021/acs.analchem.7b01051" @default.
- W2682783302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28636329" @default.
- W2682783302 hasPublicationYear "2017" @default.
- W2682783302 type Work @default.
- W2682783302 sameAs 2682783302 @default.
- W2682783302 citedByCount "24" @default.
- W2682783302 countsByYear W26827833022018 @default.
- W2682783302 countsByYear W26827833022019 @default.
- W2682783302 countsByYear W26827833022020 @default.
- W2682783302 countsByYear W26827833022021 @default.
- W2682783302 countsByYear W26827833022023 @default.
- W2682783302 crossrefType "journal-article" @default.
- W2682783302 hasAuthorship W2682783302A5022889126 @default.
- W2682783302 hasAuthorship W2682783302A5042973046 @default.
- W2682783302 hasAuthorship W2682783302A5045389279 @default.
- W2682783302 hasAuthorship W2682783302A5052077609 @default.
- W2682783302 hasAuthorship W2682783302A5052342599 @default.
- W2682783302 hasAuthorship W2682783302A5063499064 @default.
- W2682783302 hasAuthorship W2682783302A5072580346 @default.
- W2682783302 hasConcept C108625454 @default.
- W2682783302 hasConcept C111919701 @default.
- W2682783302 hasConcept C158650290 @default.
- W2682783302 hasConcept C161790260 @default.
- W2682783302 hasConcept C178790620 @default.
- W2682783302 hasConcept C185592680 @default.
- W2682783302 hasConcept C191015642 @default.
- W2682783302 hasConcept C197404232 @default.
- W2682783302 hasConcept C206212055 @default.
- W2682783302 hasConcept C21951064 @default.
- W2682783302 hasConcept C2777313579 @default.
- W2682783302 hasConcept C2779938440 @default.
- W2682783302 hasConcept C2781188995 @default.
- W2682783302 hasConcept C41008148 @default.
- W2682783302 hasConcept C43617362 @default.
- W2682783302 hasConcept C55493867 @default.
- W2682783302 hasConcept C60644358 @default.
- W2682783302 hasConcept C86803240 @default.
- W2682783302 hasConceptScore W2682783302C108625454 @default.
- W2682783302 hasConceptScore W2682783302C111919701 @default.
- W2682783302 hasConceptScore W2682783302C158650290 @default.
- W2682783302 hasConceptScore W2682783302C161790260 @default.
- W2682783302 hasConceptScore W2682783302C178790620 @default.
- W2682783302 hasConceptScore W2682783302C185592680 @default.
- W2682783302 hasConceptScore W2682783302C191015642 @default.
- W2682783302 hasConceptScore W2682783302C197404232 @default.
- W2682783302 hasConceptScore W2682783302C206212055 @default.
- W2682783302 hasConceptScore W2682783302C21951064 @default.
- W2682783302 hasConceptScore W2682783302C2777313579 @default.
- W2682783302 hasConceptScore W2682783302C2779938440 @default.
- W2682783302 hasConceptScore W2682783302C2781188995 @default.