Matches in SemOpenAlex for { <https://semopenalex.org/work/W2683363191> ?p ?o ?g. }
Showing items 1 to 52 of
52
with 100 items per page.
- W2683363191 abstract "e13092 Background: No comprehensive breast cancer risk assessment model for Japanese women exists. Consequently, we have collected Japanese women’s data to investigate key BC risk factors with an objective of deriving a Japanese-women specific BC risk assessment model. Methods: We conducted a retrospective case-control study (paper-based with postal survey) at 15 institutions during 2014-2015. A survey was distributed to Japanese females aged 20-80 who had BC check-up. All pertinent data of a total of 34 factors including demographic and reproductive factors, social history and eating habits was collected. Cases and controls were divided into three groups respectively, premenopausal (PRE; 20 ≤ age < 45), perimenopausal (PERI; 45 ≤ age ≤ 55) and postmenopausal group (POST; 55 < age ≤ 80). Cases and control variables were compared by t-test, chi-square test and Wilcoxon rank sum test. Preliminary BC risk was calculated by logistic regression analysis. Results: A total of 3975 female Japanese datasets were collected, of which 2494 were complete (all variables present) with 1401 controls and 1093 cases were used. There were 222 cases and 332 controls for PRE, 404 cases and 537 controls for PERI, and 467 and 532 controls for POST. The univariate analysis demonstrated that BMI was significantly higher in cases than in controls in all groups (P < 0.01) as was “number of deliveries” in PRE and POST (P < 0.001) and Brinkman index in PRE and PERI (p = 0.017). Multivariate analysis revealed that BC risk was positively associated with BMI (OR 1.080, 95% CI 1.017–1.148, p = 0.012) in PRE, BMI (OR 1.121, 95% CI 1.072–1.174, p < 0.01) and brinkman index (OR 1.000005, 95% CI 1.000002–1.000008, p < 0.01) in PERI, age (OR 1.054, 95% CI 1.028–1.081, p < 0.010), BMI (OR 1.153, 95% CI 1.076-1.171, p < 0.01) and family history (OR 1.497, 95% CI 1.103–2.033, p = 0.001) in POST, while negatively associated with regular exercise (OR 0.672, 95% CI 0.517–0.873, p = 0.003) in POST. Conclusions: BMI in all groups, in addition, the Brinkman index in PERI and age and family history in POST are BC risk factors. Exercise is a protective risk factor in POST. However, the preliminary results are incomplete and further analysis will be conducted before a full risk assessment model is proposed for Japanese women." @default.
- W2683363191 created "2017-06-30" @default.
- W2683363191 creator A5010062225 @default.
- W2683363191 creator A5028127888 @default.
- W2683363191 creator A5028664306 @default.
- W2683363191 creator A5040251699 @default.
- W2683363191 creator A5043460153 @default.
- W2683363191 creator A5065105893 @default.
- W2683363191 creator A5084956763 @default.
- W2683363191 creator A5087348287 @default.
- W2683363191 date "2017-05-20" @default.
- W2683363191 modified "2023-09-23" @default.
- W2683363191 title "Preliminary analysis and assessment of breast cancer risk in Japanese women." @default.
- W2683363191 doi "https://doi.org/10.1200/jco.2017.35.15_suppl.e13092" @default.
- W2683363191 hasPublicationYear "2017" @default.
- W2683363191 type Work @default.
- W2683363191 sameAs 2683363191 @default.
- W2683363191 citedByCount "0" @default.
- W2683363191 crossrefType "journal-article" @default.
- W2683363191 hasAuthorship W2683363191A5010062225 @default.
- W2683363191 hasAuthorship W2683363191A5028127888 @default.
- W2683363191 hasAuthorship W2683363191A5028664306 @default.
- W2683363191 hasAuthorship W2683363191A5040251699 @default.
- W2683363191 hasAuthorship W2683363191A5043460153 @default.
- W2683363191 hasAuthorship W2683363191A5065105893 @default.
- W2683363191 hasAuthorship W2683363191A5084956763 @default.
- W2683363191 hasAuthorship W2683363191A5087348287 @default.
- W2683363191 hasConcept C121608353 @default.
- W2683363191 hasConcept C12174686 @default.
- W2683363191 hasConcept C126322002 @default.
- W2683363191 hasConcept C143998085 @default.
- W2683363191 hasConcept C29456083 @default.
- W2683363191 hasConcept C38652104 @default.
- W2683363191 hasConcept C41008148 @default.
- W2683363191 hasConcept C530470458 @default.
- W2683363191 hasConcept C71924100 @default.
- W2683363191 hasConceptScore W2683363191C121608353 @default.
- W2683363191 hasConceptScore W2683363191C12174686 @default.
- W2683363191 hasConceptScore W2683363191C126322002 @default.
- W2683363191 hasConceptScore W2683363191C143998085 @default.
- W2683363191 hasConceptScore W2683363191C29456083 @default.
- W2683363191 hasConceptScore W2683363191C38652104 @default.
- W2683363191 hasConceptScore W2683363191C41008148 @default.
- W2683363191 hasConceptScore W2683363191C530470458 @default.
- W2683363191 hasConceptScore W2683363191C71924100 @default.
- W2683363191 hasLocation W26833631911 @default.
- W2683363191 hasOpenAccess W2683363191 @default.
- W2683363191 hasPrimaryLocation W26833631911 @default.
- W2683363191 isParatext "false" @default.
- W2683363191 isRetracted "false" @default.
- W2683363191 magId "2683363191" @default.
- W2683363191 workType "article" @default.